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Musculoskeletal Biology and Bioengineering (GRS)

Gordon Research Seminar

Insight into Musculoskeletal Tissue Interfaces in Homeostasis and Disease

August 4 - 5, 2018
Chairs Brian O. Diekman and Brianne K. Connizzo
Proctor Academy
204 Main Street
Andover, New Hampshire, United States
 Venue and Travel Information

Conference Description

The Gordon Research Seminar on Musculoskeletal Biology and Bioengineering is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The focus of this meeting is investigating how different cell types and tissue systems work together to maintain normal musculoskeletal homeostasis and how these relationships are disrupted in disease and injury. We will also highlight and draw upon the perspectives of established researchers in academia, industry, and the clinic during our career development component, which will probe for their insight in pursuing new directions in the field as well as maintaining an active, multidisciplinary research program in diverse environments.

Related Meeting

This GRS will be held in conjunction with the "Musculoskeletal Biology and Bioengineering" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Strategic Directions in Musculoskeletal Research
Discussion Leaders: Brian Diekman (University of North Carolina at Chapel Hill, USA) and Brianne Connizzo (Massachusetts Institute of Technology, USA)
3:45 pm - 3:55 pm
X. Edward Guo (Columbia University, USA)
"Bone Bioengineering and Beyond"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 4:10 pm
Vicki Rosen (Harvard School of Dental Medicine, USA)
"Skeletal BMP Signaling in Health and Disease"
4:10 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
Michael Yaszemski (Mayo Clinic, USA)
"Bedside to Bench and Back: Musculoskeletal Tissue Engineering"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Biological Transitions in the Musculoskeletal System
Discussion Leaders: Stephanie Cone (North Carolina State University / University of North Carolina at Chapel Hill, USA) and Tonia Tsinman (University of Pennsylvania, USA)
7:30 pm - 7:45 pm
Sean Flannery (Brown University, USA)
"Assessing Meniscus Health Post-ACL Repair with MRI T2* Relaxometry"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Trupti Trivedi (Indiana University-Purdue University Indianapolis, USA)
"Bone Derived Excess TGF-β Impairs Glucose Metabolism and Insulin Release in Mice with High Bone Turnover"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Raul Sun Han Chang (University of Illinois at Urbana-Champaign, USA)
"Triphasic Biomaterial for Enhanced Toughness and Regenerative Healing of the Osteotendinous Junction"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Yamini Krishnan (Massachusetts Institute of Technology, USA)
"Developing an In Vitro Cartilage Synovium Co-Culture Model for Post-Traumatic Osteoarthritis"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Pamela Cabahug-Zuckerman (New York University, USA)
"Age-Related Changes in Load-Induced Skeletal Stem Cell Location and Activation"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Rachel Nordberg (University of North Carolina at Chapel Hill / North Carolina State University, USA)
"Investigation of Multi-Phasic 3D-Bioplotted Scaffolds for Site-Specific Chondrogenic and Osteogenic Differentiation of Human Adipose Derived Stem Cells for Osteochondral Tissue Engineering Application"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Translational Research in Musculoskeletal Biology
Discussion Leaders: Claire Dooley (Regenerative Medicine Institute (REMEDI), National University of Ireland Galway, Ireland) and Sun Peck (University of Pennsylvania, USA)
9:00 am - 9:15 am
David Browe (Trinity College Dublin, Ireland)
"Evaluation of Decellularized Extracellular Matrices Derived from Various Tissue Sources to Modulate Mesenchymal Stromal Cell Differentiation"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Benjamin Freedman (Wyss Institute for Biologically Inspired Engineering, Harvard University, USA)
"Bio-Inspired Tough Adhesives for Tendon Repair and Regeneration"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Aimee Colbath (Colorado State University, USA)
"Autologous and Pooled-Allogeneic Equine Bone Marrow-Derived Mesenchymal Stem Cells Elicit Equivalent Clinical and Cytological Effects in an Interleukin-1 Beta Inflammatory Joint Model"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Courtney Mazur (University of California, San Francisco, USA)
"Osteocytic MMP13 Regulates Perilacunar/Canalicular Remodeling, Bone Quality and Joint Disease"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Gerardo Narez (Colorado State University, USA)
"Efficacy of P188 in Saving Meniscal Cells Following Impact"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Feini Qu (Washington University in St. Louis, USA)
"Bone and Fibrous Tissue Morphogenesis During Digit Tip Regeneration in the Adult Mouse"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Effective Career Transitions in Musculoskeletal Biology and Bioengineering
This session will provide a forum for early career investigators to discuss career transitions and working relationships between industry, government, academia and the clinic, as well as to explore different career paths within these areas.
Discussion Leaders: Megan Killian (University of Delaware, USA) and Anne Gingery (Mayo Clinic, USA)
1:30 pm - 2:30 pm
Panel Discussion
Career Motion and Crossing Boundaries in Academia, Government, Industry and the Clinic
  • X. Edward Guo (Columbia University, USA)
  • Vicki Rosen (Harvard School of Dental Medicine, USA)
  • Michael Yaszemski (Mayo Clinic, USA)
  • Yanming Bi (Center for Scientific Review, National Institutes of Health, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes

Contributors

Gordon Research Conferences
National Institutes of Health
Duke University - Biomedical Engineering
Integra Foundation

Funding for this conference was made possible (in part) by (1 R13AR73652-01) from the National Institute Of Arthritis And Musculoskeletal And Skin Diseases (NIAMS). The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

Conference Links

Conference History Musculoskeletal Biology and Bioengineering
Additional Fee Info

Musculoskeletal Biology and Bioengineering
August 4 - 9, 2024


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