Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Plans, Strategies and Surprises Along My Career Path
Discussion Leaders: Sun Peck (Vanderbilt University Medical Center, United States) and Stefaan Verbruggen (University of Sheffield, United Kingdom)
3:45 pm - 4:15 pm
Martha Murray (Boston Children's Hospital, United States)
"Lost in Translation - One Surgeon's Career Path"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Exploring the Spatial Context of Musculoskeletal Tissues Through Imaging and Genomics
Discussion Leader: Nicole Migotsky (Washington University in St. Louis, United States)
7:30 pm - 7:50 pm
Belle Creith (University of Southampton, United Kingdom)
"Disclosing Diagnostic Collagen Phenotypes in Osteosarcoma Biopsies with Second Harmonic Generation Imaging"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:15 pm
Dominique Barnes (Brown University, United States)
"Post-Surgical Metal Wear Particle Artifact Correction in Magnetic Resonance Imaging by Deep Neural Networks"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:40 pm
Nicole Zimmer (Duke University, United States)
"Resting Supine for 45 Minutes Mitigates Diurnal Changes in Intervertebral Disc Height"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 9:05 pm
Severin Ruoss (University of California San Diego, United States)
"Spatial Transcriptomics in Skeletal Muscle"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Serra Kaya (University of California San Francisco, United States)
"Prioritization of Genes Relevant to Human Osteoarthritis Through the Unbiased Integration of Aging Mouse Bone Transcriptomics and Human GWAS Analyses"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
New Strategies in Musculoskeletal Pathology, Regeneration, and Healing
Discussion Leaders: Aniket Jana (University of Maryland, United States) and Fei San Lee (University of Nebraska-Lincoln, United States)
9:00 am - 9:15 am
Margaret Vyhlidal (University of Alberta, Canada)
"Transcriptomic Evidence Supporting a Mechanotransductive Role of Caveolae in Human Meniscus Fibrochondrocytes"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Priscilla Tjandra (University of California Davis, United States)
"Systemic Bone Loss after Myocardial Infarction Is Not Mitigated in Complement 5aR1 Knockout Mice"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Chrisanne Dsouza (McGill University/Shriners Hospitals for Children, Canada)
"Resistance to Membrane Injury and Mechanotransductive Calcium Signaling in Aging Osteoblasts and Osteoclasts"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Timur Kamalitdinov (University of Pennsylvania, United States)
"Targeting Hedgehog Signaling to Improve Tendon-to-Bone Repair"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Markia Bowe (University of Florida , United States)
"Subchondral Bone Remodeling Differs for Anterior Cruciate Ligament and Medial Meniscus Injury Models of Post-traumatic Knee Osteoarthritis"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Meagan Makarczyk (University of Pittsburgh, United States)
"An Innervated Synovium-Cartilage Chip for Modeling Joint Inflammation and Associated Pain"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Insights Into Careers in the Musculoskeletal Field
Discussion Leaders: Sun Peck (Vanderbilt University Medical Center, United States)
1:30 pm - 2:00 pm
Martha Murray (Boston Children's Hospital, United States)
"Insights into Careers in the Musculoskeletal Field"
2:00 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes