Sunday Evening
Session #1: Recent Human Intoxications and Newly Defined Risks - 7:30-10:00 pm
Chair: Ian R. Falconer , University of Adelaide
- 7:30 - Welcome and Organizational Comments
- 7:50 - Overview by Chair
- 8:00 - W. Wayne Carmichael, Wright State University - "Human Toxicoses in Brazil Following Exposure to Microsystin-LR"
- 8:30 - Bruce B. Jarvis , University of Maryland - "Mycotoxins in Indoor Air: A Case Study of Stachybotrys Involved Infant Pulmonary Bleeding"
- 9:00 - Dorr G. Dearborn , Case Western Reserve University - "Human Toxicoses Following Exposure to Stachybotrys atra in Indoor Air"
- 9:30 - General Discussion
- 10:00 - Social
Monday Morning
Session #2: Emerging and Re-emerging Toxins/Toxicoses - 9:00-12:30 pm
Chair: Gregory M. Patterson, University of Hawaii
- 9:00 - Overview by Chair
- 9:10 - Geert B. Janssen, National Institute of Public Health - "Aspects of the Non-linear Toxicity Dose Response Curve of lfa-Ergocryptine"
- 9:50 - Michael J. Holmes, National University of Singapore - "Toxic Benthic Dinoflagellates, Gambierdiscus yasumotoi, G. toxicus var. belizeanus and Coolia monotis"
- 10:30 - Coffee
- 11:00 - Raghubir P. Sharma, University of Georgia - "Effects of Mycotoxins in Cytokines"
- 11:45 - General Discussion
Monday Evening
Session #3: Molecular Targets of Toxin Action - 7:30-9:30 pm
Chair: William P. Norred , USDA, ARS, SAA
- 7:30 - Overview by Chair
- 7:40 - Charles F.B. Holmes , University of Alberta - "Elucidation of the Molecular Basis for Interaction of the Marine Toxins Okadaic Acid, Microcystin-LR and Motuporin with Protein Phosphatases"
- 8:10 - Peter D. Constable, University of Illinois - "Potential Mechanisms of Fumonisin-induced Cardiotoxicity in Swine"
- 8:40 - Dean W. Roberts, National Center for Toxicological research - "Site Directed Coupling of Fumonisin B1 for Antibody Development and Immunoaffinity Cleanup/Tandem Mass Spectrometry"
- 9:10 - General Discussion
- 9:30-11:30 - Poster Session #1: Mycotoxins
Tuesday Morning
Session #4: New Developments in Analysis and Chemistry - 9:00-12:30 pm
Chair: Peter D.R. Moeller , NOAA Southeast Fisheries Science Center
- 9:00 - Overview by Chair
- 9:10 - Stephen Naylor, Mayo Clinic - "Electrospray-Mass Spectrometry and Capillary Electrophoresis-Mass Spectrometry -- Potential Use in Mycotoxin and Phycotoxin Research"
- 9:50 - John Apsimon, Carleton University - "The Sidechain Stereochemistry of Fumonisins. Chemical Approach"
- 10:30 - Coffee
- 11:00 - Randall K. Julian, Jr., Eli Lilly and Company - "Ion Trap Mass Spectroscopy Theory and Simulation"
- 11:30 - A. J. Shaka, University of California, Irvine - "A New NMR Technique Applied to Structure, Complex Formation, and Dynamics in Solution"
- 12:00 - General Discussion
Tuesday Evening
Session #5: Neurotoxicity - 7:30-10:00 pm
Chair: Richard Lewis, University of Queensland
- 7:30 - Overview by Chair
- 7:40 - D. Steve Kerr, University of Otago School of Medicine - "A Novel Neurophysiological Approach in the Rapid Detection and Analysis of Several Marine Biotoxins"
- 8:20 - Christopher J. Gordon, US Environmental Protection Agency - "Behavioral Thermoregulatory Control of Body Temperature in the Mouse Exposed to Maitotoxin"
- 9:00 - OPEN--PHYCOTOX
- 9:15 - OPEN--MYCOTOX
- 9:30 - General Discussion
Wednesday Morning
Session #6: Mechanisms of Toxicity - 9:00-12:30 pm
Chair: Maria T.C. Runnegar, University of Southern California
- 9:00 - Overview by Chair
- 9:10 - Clinton Jones, University of Nebraska - "Regulation of Cellular Growth by Fumonisin B1"
- 9:50 - Richard E. Honkanan , University of South Alabama - "Serine/Threonine Protein Phosphatase Inhibitors and the Cell Cycle"
- 10:30 - Coffee
- 11:00 - Frances M. VanDolah, NOAA Southeast Fisheries Science Center - "A Role for Okadaic Acid in Growth Competition in the Ciguatera Dinoflagellate Assemblage"
- 11:30 - Victoria L. Stevens, Emory University School of Medicine - "Fumonisin B1 Inhibition of Vitamin Uptake Mediated by GPI-Anchored Folate Receptor"
- 12:00 General Discussion
Wednesday Evening
Session #7: Unveiling the Complexity of Toxin Metabolism - 7:30-10:00 pm
Chair: Joanne Fink-Gremmels, Utrecht University
- 7:30 - Overview by Chair
- 7:40 - Steve Musser, US Food and Drug Administration - "Brevetoxin Metabolism in Shellfish"
- 8:20 - Christian Schlatter, University of Zurich - "Kinetic and Mechanistic Aspects of Ochratoxin A Carcinogenicity"
- 9:00 - OPEN - Phycotox Poster
- 9:15 - OPEN - Phycotox Poster
- 9:30 - General Discussion
- 10:00-11:30 - Poster Session #2: Phycotoxins
Thursday Morning
Session #8: Evaluation of Toxin Exposure: Toxin Identification and Biomarkers - 9:00-12:15 pm
Chair: Gordon S.Shepherd, PROMEC Medical Research Council
- 9:00 - Overview by Chair
- 9:10 - Christopher P. Wild , University of Leeds - "Molecular Epidemiology of Mycotoxins"
- 9:50 - Sherwood Hall , U.S. FDA, - "PSP Accumulation in Humans Following the Kodiak, Alaska Exposure"
- 10:30 - Coffee
- 11:00 - Gregory Bossert, University of Miami School of Medicine - "Brevetoxicosis in Manatees from the 1996 Epizootic"
- 11:45 - General Discussion
Thursday Evening
Session #9: Implications for Food Safety - 8:00-10:00 pm
Chair: J. David Miller, Agriculture Canada
- 8:00 - Overview by Chair
- 8:10 - Paul C. Howard, US Food and Drug Administration - "The Consequences of Fumonisin B1 Exposure in vitro in Human Cells, and in vivo in B6C3F1 Mice and F344 Rats"
- 8:50 - Robert W. Dickey, US Food and Drug Administration - "Performance Characteristics of Methods for the Determination of Brevotoxins in Shellfish Applied During the Gymnodinium breve Red Tide in the Northern Gulf of Mexico, 1996-97"
- 9:30 - General Discussion
|
