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SESSION I
SUNDAY PM
RE-EMERGING TOXICOSES AND UNUSUAL MORTALITY EVENTS
7:30 - 7:45 OVERVIEW OF PRESENTATIONS
CHAIRPERSON: W.F.O. Marasas, PROMEC, South Africa
DISCUSSION LEADER: Michael Holmes, National University of Singapore
7:45 - 8:10 Growth of aflatoxic strains of Aspergillus flavus on areca nuts
Hester Vismer, PROMEC, South Africa
8:10 - 8:35 Characteristics of Wellington Harbour toxins derived from the summer of 1998 toxic Gymnodinium outbreak
F. Hoe Chang, National Institute of Water & Atmospheric Research, New Zealand
8:35 - 9:00 Spirolides: novel toxic imines in plankton and shellfish from Nova Scotia
Allan Cembella, National Institute of Water & Atmospheric Research, New Zealand
9:00 - 9:25 Occurrences of PSP in Southeast Asia
Lourdes Cruz, University of the Philippines
9:25 - 9:45 California sea lion mortality event associated with trophic transfer of domoic acid
Frances Gulland, Marine Mammal Center, California
9:45- 10:00 Discussion
SESSION II
MONDAY AM
LARGE SCALE EPIDEMIOLOGY AND REGIONAL STUDIES
9:00 - 9:05 INTRODUCTION TO KEYNOTE LECTURE
CHAIRPERSON: Jeffrey Wright, National Research Council, CANADA
KEYNOTE LECTURE
9:05 - 10:00 Human Biomonitoring of Aflatoxin Exposures: Implications for Policy and Prevention
John Groopman, Johns Hopkins University
10:00 - 10:15 Discussion
10:15 - 10:30 Coffee Break
10:30 - 10:45 OVERVIEW OF PRESENTATIONS
CHAIRPERSON AND DISCUSSION LEADER: Jeffrey Wright, National Research Council, CANADA
10:45 - 11:15 Eutrophication and the Spread of Pseudo-nitzschia in the Gulf of Mexico
Quay Dortch, Louisiana Universities Marine Consortium
11:15 - 11:45 Neuropsychologic testing of individuals in Pfiesteria-contaminated riverways
Lynn Grattan, University of Maryland
11:45 - 12:00 Discussion
SESSION III
MONDAY PM
MOLECULAR TARGETS FOR TOXINS
7:30 - 7:45 OVERVIEW OF PRESENTATIONS
CHAIRPERSON: Ronald T. Riley, U.S. Department of Agriculture
DISCUSSION LEADER: Vera Trainer, NOAA-National Marine Fisheries Service
7:45 - 8:15 Molecular targets for thichothecenes
James Pestka, Michigan State University
8:15 - 8:45 Ceramide Synthase, a target enzyme for fumonisin inhibition: An enrichment scheme towards protein purification
Ronald Jenkins, U.S. Food and Drug Administration
8:45 - 9:15 Brevetoxin induction of neurotoxicity in cultured cerebellar granule cells
Thomas Murray, University of Georgia
9:15 - 9:45 Molecular targets for brevetoxins
Daniel Baden, University of North Carolina Wilmington
9:45- 10:00 Discussion
SESSION IV
TUESDAY AM
BIOLOGICAL AND GENETIC CONTROL MEASURES
9:00 - 9:20 OVERVIEW OF PRESENTATIONS
CHAIRPERSON: Thomas E. Cleveland, U.S. Department of Agriculture
DISCUSSION LEADER: Thomas Hohn, Novartis
9:20 - 9:50 Genetic degradation of fumonisin in corn
Jonathan Duvick, Pioneer Hi-Bred International
9:50 - 10:20 Modulation of lipid metabolism in Aspergillus/host plant interactions: a potential means to control aflatoxin contamination
Nancy Keller, Texas A&M University
10:20 - 10:30 Discussion
10:30 - 10:45 COFFEE BREAK
10:45 - 11:15 Algicidal bacteria as natural regulators of harmful algal bloom dynamics
Gregory Doucette, NOAA-National Ocean Service
11:15 - 11:45 Selecting the microbes with which we live
Peter J. Cotty, U.S. Department of Agriculture
11:45 - 12:00 Discussion
SESSION V
TUESDAY PM
PHYSICIAL CONTROL MEASURES
7:30 - 7:50 OVERVIEW OF PRESENTATIONS
CHAIRPERSON: Wanda Haschek-Hock, University of Illinois
DISCUSSION LEADER: Richard Greene, U.S. Environmental Protection Agency
7:50 - 8:20 Use of clay flocculants in physical control of mycotoxins
Tim Phillips, Texas A&M University
8:20 - 8:50 Use of clay flocculants in physical control of harmful algal blooms
Don Anderson, Woods Hole Oceanographic Institution
8:50 - 9:05 Discussion
INVITED STUDENT PRESENTATIONS
9:10 - 9:25 Student 1:
9:30 - 9:45 Student 2:
9:45 - 10:00 Student 3:
SESSION VI
WEDNESDAY AM
GENETICS AND MOLECULAR BIOLOGY OF TOXIN PRODUCTION
9:00 - 9:20 OVERVIEW OF PRESENTATIONS
CHAIRPERSON: Gary Payne, North Carolina State University
DISCUSSION LEADER: Gaspar Taroncher, Massachusetts Institute of Technology
9:20 - 9:50 Molecular analysis of saxitoxin biosynthetic genes in a toxic bacterium, Pseudomonas stutzeri
F.G. Plumley, University of Alaska.
9:50 - 10:20 Genetics of fumonisin production
Robert Proctor , U.S. Department of Agriculture
10:20 - 10:30 Discussion
10:30 - 10:45 COFFEE BREAK
10:45 - 11:15 Microcystin synthetase: genes and enzymes
Thomas Boerner, Humboldt-Universitaet, Berlin
11:15 - 11:45 Molecular biology of aflatoxin biosynthesis in Aspergillus parasiticus
Deepak Bhatnagar; U.S. Department of Agriculture
11:45 - 12:00 Discussion
SESSION VII
WEDNESDAY PM
NEW DEVELOPMENTS IN DETECTION OF ORGANISMS AND TOXINS
7:30 - 7:45 OVERVIEW OF PRESENTATIONS
CHAIRPERSON: David Oldach, University of Maryland
DISCUSSION LEADER: Bruce Jarvis, University of Maryland
7:45 - 8:15 Development of ribosomal gene probes for detection of Pfiesteria piscicida
Parke Rublee, University of North Carolina
8:15 - 8:45 Tracking Stachybotrys chartarum strains by PCR
Steve Vesper, U.S. Environmental Protection Agency
8:45 - 9:00 Discussion
SPECIAL SESSION
Summary of the Satellite Meeting on Toxin Detection Methods. Advances in Detection Methods for Mycotoxins and Phycotoxins
9:00 - 10:00 Frances VanDolah NOAA-National Ocean Service, John Richard, Romer Laboratories
SESSION VIII
THURSDAY AM
TOXIN CHEMISTRY AND ANALYSIS
9:00 - 9:20 Overview of Presentations
CHAIRPERSON: Steven Musser, U.S. Food and Drug Administration
DISCUSSION LEADER: Helen Shurtz-Rodgers, Centers for Disease Control and Prevention
9:20 - 9:50 Novel compounds from marine cyanobacteria
William Gerwick, Oregon State University
9:50 - 10:20 MS analysis of mycotoxins
Gordon Shephard, PROMEC, South Africa
10:20 - 10:30 Discussion
10:30 - 10:45 COFFEE BREAK
10:45 - 11:15 HPLC/MS/MS detection of ciguatoxins
Richard Lewis, University of Queensland
11:15 - 11:45 Sensitive mass spectrometric methods for phycotoxin analysis
Peter Moeller, NOAA-National Ocean Service
11:45 - 12:00 Discussion
SESSION IX
THURSDAY PM
IN VIVO AND IN SITU TOXICOLOGY
7:30 - 7:45 Overview of Presentations
CHAIRPERSON: Johanna Fink-Gremmels, Utrecht University
DISCUSSION LEADER: Wayne Carmichael, Wright State University
7:45 - 8:15 Fumonisin B1 stabilizes cyclin D1: a posttranslational change during rat liver carcinogenesis.
Danica Ramljak, NIH-National Cancer Institute
8:15 - 8:45 Results of Two-Year Chronic Bioassay on Fumonisin B1
Paul C. Howard, U.S. Food and Drug Administration
8:45 - 9:15 Sodium-dependent actions of ciguatoxins and brevetoxins on myelinated axons
and motor nerve terminals
Jordi Molgo, Laboratoire de Neurobiologie Cellulaire et Moleculaire, France
9:15 - 9:45 Chronic effects of brevetoxins on paradoxical temperature dysthesia.
Christopher Gordon, U.S. Environmental Protection Agency
9:45 - 10:00 Discussion
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