| Sunday |
Session 1.
Evening | Novel and Recurring Human Toxicoses |
| Chair: Wayne Bryden, University of Sydney, Sydney, Australia |
| Discussion Leader: Mark Poli, USAMRIID, Frederick, MD |
| 7:30 pm | Welcome |
| 7:40 pm | Overview |
| 7:50 pm | Azaspiracid Poisoning: Aetiology and Distribution of the Shellfish Toxins Responsible for a New Toxic Syndrome
Kevin James, Ecotoxicology Research Unit, Cork Inst. of Technology, Cork, Ireland |
| 8:20 pm | Is the High Prevalence of Neural Tube Defects Along the Texas-Mexico Border Associated with the Consumption of Corn-Based Foods?
Kate Hendricks, Infectious Disease Epidemiology & Surveillance Division, Texas Department of Health, Austin, TX |
| 8:50 pm | Pectenotoxin: An Association with Human Shellfish Poisoning in Australia and Canada?
Michael Quilliam, NRC, Halifax, Nova Scotia, Canada |
| 9:20 pm | Discussion / Hot topic* |
| 9:45 pm | Social |
| Monday |
| 8:45 am | Group Photo |
Session 2.
Morning | New Frontiers: Toxicogenomics, Biochips and Electronic Noses |
| Chair: Gary Payne, North Carolina State University, Raleigh, NC |
| Discussion Leader: Gerry Plumley, University of Alaska, Fairbanks, AK |
| 9:00 am | Introduction |
| 9:05 am | Keynote Lecture:Toxicogenomic and Proteomics- Tools Of Discovery For The Research Scientist
James Selkirk, NIEHS, Research Triangle Park, NC |
| 10:00 am | Discussion |
| 10:10 am | Coffee Break |
| 10:35 am | Overview |
| 10:45 am | Differentiation Between Mycotoxigenic and Non-Mycotoxigenic Strains of Fungi Based on Their Volatile Production Patterns Using an Electronic Nose System
Naresh Magan, Cranfield University, UK |
| 11:15 am | Multianalyte Detection Using Electronic Tongues
John McDevitt, University of Texas, Austin, TX |
| 11:45 pm | Discussion / Hot topic* |
| 12:30 pm | Lunch |
| 4:30 pm | Poster Session I |
| 6:00 pm | Dinner |
Session 3.
Evening | New Developments in Metabolism and Detection |
| Chair: Vera Trainer, NOAA, National Marine Fisheries Service, Seattle, WA |
| Discussion Leader: Mary Trucksess, CFSAN, USFDA, Washington, DC |
| 7:30 pm | Overview |
| 7:40 pm | Fluorescence Polarization As a Tool for the Determination of Fumonisin and Deoxynivalenol in Cereal Grains
Chris Maragos, USDA, Peoria, IL |
| 8:10 pm | Metabolism of Brevetoxins in Shellfish
Steve Musser, USFDA, Washington, DC |
| 8:40 pm | Acylation of Hydrolyzed Fumonisins by Ceramide Synthase to Form Toxic N-Acyl-Metabolites
Michaela Hartl, BASF AG, Limburgerhof, Germany |
| 9:10 pm | Discussion / Hot topic* |
| Posters / Social |
| Tuesday |
Session 4.
Morning | Mode of Action and Molecular Targets for Toxins: New Approaches and Advances |
| Chair: James Pestka, Michigan State University, East Lansing, M |
| Discussion Leader: Tom Murray, University of Georgia, Athens, GA |
| 9:00 am | Overview |
| 9:10 am | A Genomic Approach to Understanding Fumonisin-Induced Toxicity in Mouse Liver
Chris Corton, CIIT, Research Triangle Park, NC |
| 9:40 am | Inflammation Augments Acute Hepatotoxicity Caused by Mycotoxins
Pattie Ganey, Michigan State University, East Lansing, MI |
| 10:10 am | Discussion |
| 10:20 am | Coffee Break |
| 10:40 am | Mechanism of Action of the Putative Pfiesteria Toxin: Activation of a P2X7 Receptor Pathway
John Ramsdell, Marine Biotoxins Program, NOAA National Ocean Service, Charleston, SC |
| 11:10 am | Maitotoxin Activates a Non-selective Cation Channel and a P2C/P2X7-like Cytolytic Pore
William Schilling, Case Western Reserve University, Cleveland, OH |
| 11:40 am | Mechanisms Of Action of Polyether Toxins on Sodium Channels
David Adams, University of Queensland, Brisbane, Australia |
| 12:10 pm | Discussion / Hot topic* |
| 12:30 pm | Lunch |
| 4:30 pm | Poster Session I |
| 6:00 pm | Dinner |
Session 5.
Evening | Toxin Chemistry and Analysis |
| Chair: John Apsimon, Carleton University, Ottawa, Canada |
| Discussion Leader: Robert Gawley, University of Miami, FL |
| 7:30 pm | Overview |
| 7:40 pm | Purification and Characterization of a Toxin from Pfiesteria piscicida
Peter Moeller, Marine Biotoxins Program, NOAA National Ocean Service, Charleston, SC |
| 8:05 pm | Chlorinated Byproducts from the Treatment of the Cyanobacterial Toxin, Cylindrospermopsin
Glen Shaw, National Research Centre for Environmental Toxicology, Queensland, Australia |
| 8:30 pm | Assessing Chronic Exposure to Fumonisin Mycotoxins: The Use of Hair as a Suitable Non-Invasive Matrix
Vikash Sewram, Medical Research Council, PROMEC Unit, Tygerberg, South Africa |
| 8:55 pm | Discussion |
| 9:05 pm | Invited student presentations :
Chair W.F.O. Marasas, Medical Research Council, South Africa
(TBA: two students to be selected from poster presentations) |
| 9:30 pm | Discussion |
| 9:45 pm | Posters / Social |
| Wednesday |
Session 6.
Morning | Cellular and Environmental Control of Toxin Production |
| Chair: Deepak Bhatnagar, USDA/ARS, New Orleans, LA |
| Discussion Leader: Don Anderson, Woods Hole Oceanographic Institute, MA |
| 9:00 am | Overview |
| 9:10 am | Polyketide Biosynthesis by Dinoflagellates: Molecular Genetic Perspectives
Kelly Rein, Florida International University, Miami, FL |
| 9:40 am | Cellular and Sub-Cellular Localization of Enzymes Involved in Aflatoxin Synthesis in Aspergillus parasiticus
John Linz, Michigan State University, East Lansing, MI |
| 10:10 am | Discussion |
| 10:25 am | Evaluations |
| 10:30 am | Coffee Break |
| 11:00 am | Control of Toxin Production in Algal Cells by External Nitrogen and Phosphorus Concentrations
Edna Graneli, University of Kalmar, Kalmar, Sweden |
| 11:30 am | Impact of Corn Kernel Environment on Gene Expression and Fumonisin Biosynthesis in Fusarium verticillioides
Charles Woloshuk, Purdue University, West Lafayette, IN |
| 12:00 pm | Discussion / Hot topic* / Evaluations |
| 12:30 pm | Lunch |
| 4:30 pm | Poster Session II |
| 6:00 pm | Dinner |
Session 7.
Evening | Biological and Genetic Control Measures |
| Chair: Jonathan Duvick, Pioneer Hi Bred Seed Int., Johnston, IA. |
| Discussion Leader: Nancy Keller, University of Wisconsin, Madison, WI |
| 7:30 pm | Overview |
| 7:40 pm | Survey of the Family Bacillaceae for Biocontrol of the Endophytic State of Fusarium moniliforme in Maize and in planta Fumonisin Reduction
Charles Bacon, USDA/ARS, Athens, GA |
| 8:10 pm | Ribosomal Protein Transgene to Increase Plant Tolerance to Trichothecenes
Linda Harris, Agriculture and Agri-Food Canada, Ottawa |
| 8:40 pm | Genomic Analysis of Toxin Production by Plant Pathogenic Fungi
Olen Yoder, Torry Mesa Research Institute, San Diego, CA |
| 9:10 pm | Discussion / Hot topic* |
| Posters / Social |
| Thursday |
Session 8.
Morning | Novel Toxin Outbreaks: Environmental Implications |
| Chair: Benjamin Suarez-Isla, University of Chile, Santiago |
| Discussion Leader: Ken Voss, USDA/ARS Athens, GA |
| 9:00 am | Overview |
| 9:10 am | Widespread Environmental Impacts of Domoic Acid on the California Coast
Mary Silver, University of California at Santa Cruz, CA |
| 9:40 am | Brevetoxin Production by Chattonella in Delaware
Carm Tomas, University of North Carolina, Wilmington, NC |
| 10:10 am | Discussion |
| 10:20 am | Coffee Break |
| 10:40 am | Toxicoses in Cattle Associated with Penicillium Species
David Miller, Carleton University, Ottawa, Canada |
| 11:10 am | Domoic Acid in Scotland: Environmental, Regulatory and Political Implications
Susan Gallacher, FRS Marine Laboratory, Aberdeen, Scotland |
| 11:40 am | Discussion / Hot topic* |
| 12:00 pm | Business Meeting |
| 12:30 pm | Lunch |
| 4:30 pm | Poster Session II |
| 6:00 pm | Dinner |
Session 9.
Evening | Populations at Risk: Contributing Factors and Future Directions |
| Chair: Gerrit Speijers, National Institute of Public Health and Environment, Bilthoven, Netherlands |
| Discussion Leader: Bob MacPhail, NHEERL, EPA, Research Triangle Park, NC |
| 7:30 pm | Overview |
| 7:40 pm | Risk Assessment of Cyanobacterial Toxin Exposure
Ian Falconer , CRC for Water Quality and Treatment, Adelaide, Australia |
| 8:10 pm | Fumonisin-Induced Perturbation of Folate Transport and Neural Tube Development
Victoria Stevens, Emory University, Atlanta, GA |
| 8:40 pm | Reduction of Mycotoxin Health Risks Through the Use of Genetically Engineered Plants
Bruce Hammond, Monsanto Company, St. Louis, MO |
| 9:10 pm | Discusssion / Closing Remarks |
| 9:45 pm | Social |
