Find a Conference

Alert - GRC systems are offline for approximately one week. For more information, please click here.

Myelin

Gordon Research Conference

May 7 - 12, 2000
Chairs Steven E. Pfeiffer and Klaus-Armin Nave
Vice Chair Marie T. Filbin
Renaissance Tuscany Il Ciocco
Via Giovanni Pascoli
Lucca (Barga), Lucca, Italy
 Venue and Travel Information

Conference Program

SUNDAY, MAY 7

Arrival
posters go up
Dinner 6 - 7 pm

Molecular Architecture of Myelin-forming Cells
(7:15 - 9:15 pm)
Hans Werner Mueller (Düsseldorf), Discussion Leader
  • Shoichiro Tsukita (Kyoto) Claudin family.
  • Bob Lazzarini (for Alex Gow) (New York) OSP mediates the formation of parallel tight junction fibrils.
  • Tim Coetzee (Farmington) Myelin membrane subdomain structure and function.
  • Ian Duncan (Madison) Cytoskeletal abnormalities in oligodendrocytes of the taiep rat mutant.
MONDAY, MAY 8
Inherited & Acquired Myelin Diseases
(9:00 - 12:30 am)
Steven Scherer (Philadelphia) & Doug Arnold (Montreal), Discussion Leaders
  • Hugo Moser (Baltimore) Human genetic disorders of myelin: Adrenoleukodystrophies.
  • Volkmar Gieselmann (Kiel) Arylsulfatase knockout mice as a model for metachromatic leukodystrophy
  • Henry McFarlane (Washington D.C.) Implications of MRI on our understanding of the MS lesion.
  • Art Warrington (Rochester) Immunoglobulin Modulation of CNS Repair.
  • Bill Hickey (Lebanon) B-cell Entry in the Pathogenesis of CNS disease.
Informal afternoon sessions
Poster Session 4 - 5 pm

Stem Cells, Their Gliogenic Potential and Transplantation
(5 - 7:30 pm)
Monique Dubois-Dalcq (Paris), Discussion Leader
  • Oliver Brüstle (Bonn) Embryonic stem cell-based myelin repair.
  • Evan Synder (Boston) Neural stem cells in development and disease.
  • Ole Isacson (Boston) Development of neural and stem cells in transplantation to the adult CNS.
  • Hans Keirsted (Irvine) Remyelination following transplantation of glial-committed neural precursors.
  • Steve Goldman (Cornell) Oligoneogenic progenitor cells of the adult human white matter.
Poster Session 9 - 10:30 pm

TUESDAY, MAY 9
Experimental Genetic Models of Dys/Demyelinating Disease
(9:00-11:00 am)
Boris Zalc (Paris) & Kaz Ikenaka (Okazaki), Discussion Leaders
  • Kuni Suzuki (Chapel Hill) Cross-breeding of the twitcher mouse model.
  • Wendy Macklin (Cleveland) Transgenic approaches to investigating oligodendrocytes.
  • Larry Wrabetz & Laura Feltri (Milan) Gain of P0 function: Mouse models of hereditary neuropathies.
  • Dies Meijer (Rotterdam) Transgenic analysis of SCIP/Oct6.
  • (Short Comment). Alan Peterson (Montreal) Promoter expression.
Endogenous Mechanisms of Remyelination
(11:15 am - 12:30 pm)
Richard Reynolds (London), Discussion Leader
  • Mary Dawson (London) Characterization of NG2-expressing cells in the adult rat and human CNS.
  • Arthur Butt (London) Adult progenitors in the normal undamaged CNS.
Informal afternoon discussions
Poster Session 4 - 5 pm

Growth Factors and Extracellular Matrix
(5-7:30 pm)
Peter Brophy (Edinburgh), Discussion Leader
  • Patrick Doherty (London). Identification of functional motifs in N-cadherin that specify homophilic binding and signal transduction.
  • Terri Wood (Hershey) Growth factor interactions in oligodendrocyte generation.
  • Rashmi Bansal (Farmington) Functional analysis of the fibroblast growth factor receptors.
  • Charles ffrench-Constant (Cambridge) Integrin function during myelination.
  • Tim Vartanian (Boston) The Erb-2 gene is necessary for the development of mature oligodendrocytes.
Poster Session 9 - 10:30 pm

WEDNESDAY, MAY 10
Transcription Factors in Myelin-forming Cell Differentiation
(9 am-10:30 pm)
Chuck Stiles (Boston), Discussion leader
  • David Rowitch (Boston) Sonic hedgehog-regulated oligodendrocyte lineage genes encoding bHLH factors in the CNS.
  • Lynn Hudson (Washington D.C.) Application of microarrays to myelin biology and disease.
  • Short Talk: Hideuka Okano (Tokyo) Transcriptional regulation in myelin-forming cells.
Additional Frontiers
(11:00 - 12:15 am)
Melitta Schachner (Hamburg), Discussion Leader
  • Mark Ellisman (San Diego) Electron tomography of the node of Ranvier
  • Roger Schnaar (Baltimore) Gangliosides as functional MAG ligands.
  • Randy McKinnon (Piscataway) Signal transduction in oligodendrocyte development.
Immunology, or Not, of Demyelinating Disease
(5:30 - 7:30 pm)
Chris Linington, Discussion Leader
  • Chris Linington (München) Genetic regulation of MOG expression modulates remyelination in EAE.
  • Rudolph Martini (Würzburg) Demyelination in heterozygous P0-deficient mice: Functional involvement of immune cells.
  • Anura Rambukkana (New York) Demyelination in the absence of immune response: A lesson from Microbacterium leprae infection.
  • John Steeves (Vancouver) Transient immunological suppression of CNS myelin to facilitate axonal regeneration.
Poster Session 9 - 10:30 pm

THURSDAY, MAY 11
Regeneration & Repair of Neurons
(9:00 - 11:00 am)
Marie Filbin & Keichii Uyemura, Discussion Leaders
  • Joel Levine (Stony Brook) Inhibitory Proteogylcans & Glial Scars.
  • Lisa McKerracher (Montreal) Overriding myelin-derived growth inhibition to stimulate axon regeneration in the CNS.
  • Marie Filbin (New York) Overcoming Inhibitors of Regeneration; Clues from Development.
  • John Steeves (Vancouver) Transient Immunological Suppression of CNS Myelin to Facilitate Axonal Regeneration.
  • Short Talk: Thomas Oertel (Zurich) No-Go? A novel neurite growth inhibitory protein.
Deconstructing Myelin Genes
(11:30 am - 12:30 pm)
Ueli Suter, Discussion Leader
  • Bob Skoff (Detroit) Myelin genes PLP and MBP are expressed in many tissues.
  • Tony Campagnoni (Los Angeles) PLP and Golli-MBP in immune response.
Molecular Structure of the Node of Ranvier
(5 - 7:30 pm)
Peter Shrager (Rochester), Discussion Leader
  • Ori Peles (Rehovot) Caspr protein family and the organization of axonal domains in myelinated fibers.
  • Lori Isom (Ann Arbor) Sodium channel ß subunits are cell adhesion molecules: interactions with extracellular matrix and the cytoskeleton
  • James Salzer (New York) Initial events in node and paranode formation.
  • Stephen Lambert (Worcester) Differential trafficking of ankyrins and their binding proteins in axonal polarity.
  • Short Talk: S. Rock Levinson (Denver) Differential localization of sodium channel isoforms at the node of Ranvier
  • Short Talk: François Couraud (Marseille) Interactions between neuronal sodium channels and the cytoskeleton.
Conference Banquet

FRIDAY, MAY 12

Morning Departure

Contributors

We gratefully acknowledge the following organizations for their financial support:

Aventis Pharmaceuticals
Beckman Coulter
Biogen
Dompè Biotec
Hoechst Marion Roussel
International Society for Neurochemistry
Max Planck Institute of Experimental Medicine
Schering AG Berlin
The Miami Project to Cure Paralysis
The Multiple Sclerosis Society of Great Britain and Northern Ireland
The Multiple Sclerosis Society of Canada
The National Multiple Sclerosis Society USA

Conference Links

Conference History
Additional Fee Info

Glial Biology: Functional Interactions Among Glia and Neurons
March 9 - 14, 2025
In Vivo Magnetic Resonance
July 14 - 19, 2024


Contact Us

MyGRC Account
Check your application status, complete your registration, update your poster, change your rooming preference, make a bus reservation, print an invitation letter, print a receipt (which includes verification that you are presenting a poster) or print an invoice by logging into your account.

GRC Venues
Everything you need to know, to plan your trip.

FAQs
Instant answers to common questions.

Tell us how we can help

Call us and leave a detailed message at: 401-783-4011

*This voicemail is only checked once daily. Due to high volume of requests during the conference season, responses may be delayed.

You have no notifications