SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in / Posters go up |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Keynote Lecture |
| Welcome: B. Zalc (INSERM U495, Paris) |
| Introduction: Robert H. Miller (Case Western Reserve University, Cleveland) |
| Nicole LeDouarin (Academie des Sciences, Paris) "The neural crest: a pluripotent structure of the Vertebrate embryo" |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Membrane and myelin structure |
| Discussion leaders: David Colman (The Montreal Neurological Institute) & Anthony Campagnoni (UCLA Medical School, Los Angeles) |
9:00 am - 9:15 am | Introductory remarks: David Colman |
9:15 am - 9:45 am | Bob Gould (University of Illinois, Chicago) "Myelination did not begin nor will it end with furry creatures" |
9:45 am - 10:15 am | Jacqueline Trotter (University of Mainz) "Oligodendroglial membrane dynamics in progenitor cells and myelinating oligodendrocytes" |
10:15 am - 11:00 am | Coffee Break |
11:00 am - 11:30 am | Conference Photo |
11:30 am - 12:00 pm | Steve Pfeiffer (University of Connecticut Medical School, Farmington) "The Myelin-Axolemmal Complex: Proteomic Analysis of Signal Transduction Mediated by Lipid Rafts" |
12:00 pm - 12:30 pm | Nicole Schaeren-Wiemers (University Hospital Basel) "The raft-associated protein MAL is required for maintenance of proper axon-glia interactions in the central nervous system" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Informal afternoon discussions |
4:00 pm - 5:00 pm | Poster Session |
5:20 pm - 7:30 pm | Multiple Sclerosis |
| Discussion leader: Catherine Lubetzki (INSERM U495, Paris) |
5:20 pm - 5:30 pm | Introductory remarks: Catherine Lubetzki |
5:30 pm - 6:00 pm | Cedric Raine (Albert Einstein College orf Medicine, Bronx) "Receptor crosstalk between oligodendrocytes and other glial cells: Relevance to multiple sclerosis" |
6:00 pm - 6:30 pm | Claudia Luchinetti (Mayo Clinic, Rochester) "Pathologic Heterogeneity in Multiple Sclerosis: Pathogenic and Clinical Implications" |
6:30 pm - 7:00 pm | Alastair Compston (University of Cambridge Clinical School, Cambridge) "Genetic analysis of multiple sclerosis" |
7:00 pm - 7:30 pm | Massimo Filippi (Scientific Institute Hop San Raffaele, Milano)
"Mechanisms of disability accumulation in MS studied using MR-based techniques" |
8:00 pm | Dinner |
9:00 pm | Poster Session |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Animal models of demyelination |
| Discussion leaders: Sam Ludwin (Queens University, Kingston) & Anne Baron van Evercooren (INSERM U546, Paris) |
9:00 am - 9:10 am | Introductory remarks: Sam Ludwin |
9:10 am - 9:50 am | Klaus Nave (Max-Planck-Institute of Experimental Medicine, Göttingen)
"Conditional mouse mutants lacking cholesterolbiosynthesis" |
9:50 am - 10:30 am | Brian Popko (University of Chicago, Chicago) "Interferon gamma's effects on oligodendrocytes: a Delphian sword?" |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:30 am | Richard Ransohoff (Cleveland Clinic Foundation, Cleveland)
"Control of microglial activation by chemokines and chemokine receptors" |
11:30 am - 12:00 pm | Steve Levison (Penn State College of Medicine, Hershey)
"Progenitor Cell Loss as a Component of Perinatal White Matter Damage" |
12:00 pm - 12:30 pm | Emiliana Borelli (Institut de Genetique et Biologie Moleculaire, Strasbourg) "An inducible cell ablation system to analyze oligodendrocyte function in vivo" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Informal afternoon discussions |
4:00 pm - 5:00 pm | Poster Session |
5:20 pm - 7:30 pm | Subspecialization of myelin |
| Discussion leaders: Elior Peles (Weizmann Institute of Science, Rehovot) |
5:20 pm - 5:30 pm | Introductory remarks: Elior Peles |
5:30 pm - 6:00 pm | Jean Antoine Girault (INSERM U536, Paris) "A role for schwannomin in the organization of nodal regions in the peripheral nervous system" |
6:00 pm - 6:30 pm | Matthew Rasband (University of Connecticut Health Center, Farmington) |
6:30 pm - 7:00 pm | Peter Brophy (University of Edinburgh)
"Glial contributions to axon-glial interaction" |
7:00 pm - 7:30 pm | Bettina Winckler (Mount Sinai School of Medicine, New York)
"Keeping proteins in check: Diffusion barriers in the axonal initial segment" |
8:00 pm | Dinner |
9:00 pm | Poster Session |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Molecular control of migration of myelin forming cells |
| Discussion leaders: Jim Goldman (Columbia University, New York)
& Tim Kennedy (Montreal Neurological Institute) |
9:00 am - 9:10 am | Introductory remarks: Jim Goldman |
9:10 am - 9:50 am | Salvador Martinez (CSIC-UMH, Alicante) "Mapping the pathways of migration of oligodendrocyte in the brain" |
9:50 am - 10:30 am | Nobuaki Tamamaki (Kyoto University)
"Heterogeneity found in the oligodendrocyte precursor cells in the murine optic nerve" |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:30 am | Jean Leon Thomas (INSERM U495, Paris) "Entering the optic nerve: molecular cues for OPCs" |
11:30 am - 12:00 pm | Hui-Hsin Tsai (Case Western Reserve University, Cleveland) "Mechanisms of oligodendrocyte precursor migration in the spinal cord" |
12:00 pm - 12:30 pm | Maria Elena de Bellard (Caltech, Los Angeles)
"Dual function of Slit as chemorepulsive and chemotactic molecule on neural crest cells" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Informal afternoon discussions during excursion to Lucca |
4:00 pm - 5:00 pm | Poster Session |
5:20 pm - 7:30 pm | Oligodendroglioma and Schwannoma |
| Discussion leader: Ueli Suter (ETH, Zürich) |
5:20 pm - 5:30 pm | Introductory remarks: Ueli Suter |
5:30 pm - 6:00 pm | David Rowitch (Dana-Farber Cancer Institute, Cambridge USA)
"Olig Function In CNS Development and Tumorigenesis" |
6:00 pm - 6:30 pm | Eric Holland (Memorial Sloan-Kettering, New York)
"Maintenance of the oligodendroglioma neoplastic phenotype" |
6:30 pm - 7:00 pm | Bill Weiss (UCSF, San Francisco)
"S100b, stem cells, and mouse models for oligodendroglioma" |
7:00 pm - 7:30 pm | Luis Parada (University of Texas, Dallas)
"Modeling Neurofibromatosis in the Mouse" |
8:00 pm | Dinner |
9:00 pm | Poster Session |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Signaling to and by myelin forming cells |
| Discussion leaders: Marie Filbin (Hunter College, New York)
& Douglas Fields (National Institutes of Health, Bethesda) |
9:00 am - 9:10 am | Introductory remarks: Marie Filbin |
9:10 am - 9:50 am | Charles Ffrench-Constant (University of Cambridge, UK)
"Regulation of growth factor signalling by integrins" |
9:50 am - 10:30 am | Carmen Birchmeier (Max-Delbrück-Centrum, Berlin)
"The function of the Neuregulin/ErbB signalling system in development of the nervous system" |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:30 am | Terri Wood (Penn State University, Hershey)
"Convergence of Signaling Pathways on Cell Cycle Targets in Oligodendrocyte Progenitors" |
11:30 am - 12:00 pm | Rashmi Bansal (University of Connecticut Medical School, Farmington) "FGF receptor signaling in the regulation of oligodendrocyte differentiation" |
12:00 pm - 12:30 pm | Kaz Ikenaka (National Institute for Physiological Science, Okazaki) "Abnormal signaling in a very early stage and a chronic demyelinating stage during demyelination" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Informal afternoon discussions |
4:00 pm - 5:00 pm | Business Meeting |
5:20 pm - 7:30 pm | Regeneration |
| Discussion leaders: Monique Dubois-Dalcq (Institut Pasteur, Paris)
& Richard Reynolds (Imperial College London) |
5:20 pm - 5:30 pm | Introductory remarks: Monique Dubois-Dalcq |
5:30 pm - 6:00 pm | Jean Merrill (Aventis Pharmaceuticals, Bridgewater)
"Oligodendrocyte Protection and Differentiation as Therapeutic Approaches for Treating MS" |
6:00 pm - 6:30 pm | Gianvitto Martino (San Raffaele Scientific Institute, Milano)
"Neuroprotection in multiple sclerosis: the role of neural stem cells" |
6:30 pm - 7:00 pm | Robin Franklin (University of Cambridge, UK) "Mechanisms of CNS remyelination" |
7:00 pm - 7:30 pm | Frank Walsh (Wyeth Research, Princeton)
"New drug discovery opportunities for regeneration" |
8:00 pm | Conference Banquet & Farewell Party |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |