| SUNDAY |
| 4:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Keynote Lecture |
| 7:30 pm - 8:00 pm | Welcome: Robert Miller (Case Western Reserve University, Cleveland, Ohio USA) |
| 8:00 pm - 8:15 pm | Introduction: Peter Brophy (University of Edinburgh, Edinburgh, Scotland) |
| 8:15 pm - 9:15 pm | Keynote: John Griffin (Johns Hopkins University, Baltimore, Maryland USA)
"What Does Myelination Do?" |
| 9:15 pm - 9:30 pm | General Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Pathologies of Myelin and Myelin-forming Cells: CNS and PNS |
| Discussion Leaders: Bruce Trapp (Cleveland Clinic Foundation, Cleveland, Ohio USA) & Matthew Rasband (University of Connecticut Health Center, Farmington, Connecticut USA) |
| 9:00 am - 9:10 am | Introductory remarks: Bruce Trapp |
| 9:10 am - 9:30 am | Jim Salzer (New York University, New York USA)
"Axonal regulation of Glial ensheathment and Myelination" |
| 9:30 am - 9:50 am | Sanjay Keswani (Johns Hopkins University, Baltimore, Maryland USA)
"Axonal protection by Myelin Associated Glycoprotein" |
| 9:50 am - 10:00 am | General Discussion |
| 10:00 am | Coffee Break |
| 10:35 am - 10:55 am | Elior Peles (Weizmann Institute of Science, Rehovot, Israel)
"Axon-glia interaction mediated by cell adhesion molecules" |
| 10:55 am - 11:15 am | Bruce Trapp (Cleveland Clinic Foundation, Cleveland, Ohio USA)
"Neuroprotection and Myelin Structure: Roles of P0 and PLP" |
| 11:15 am | Conference Photo |
| 11:40 am - 12:00 pm | Steve Miller (Northwestern University, Chicago, Illinois, USA)
"The CNS as a Neo-Lymphoid Organ? - Differential Requirements for Activation of Naive and Memory T Cells" |
| 12:00 pm - 12:30 pm | General Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Axonal-glial interchanges: Generation and Regeneration |
| Discussion Leader: Marie Filbin (Hunter College of CUNY, New York USA) |
| 7:30 pm - 7:40 pm | Introductory remarks: Marie Filbin |
| 7:40 pm - 8:00 pm | Guo-li Ming (Johns Hopkins University, Baltimore, Maryland USA)
"MAG signaling at the nerve growth cone" |
| 8:00 pm - 8:20 pm | Zhigang He (Harvard Medical School, Cambridge, Massachusetts USA)
"NAD and axon protection in EAE models" |
| 8:20 pm - 8:40 pm | Tim Vartanian (Harvard University, Cambridge, Massachusetts USA)
"The Toll-MyD88 pathway in axonal and neuronal responses to CNS injury" |
| 8:40 pm - 9:00 pm | Mitchell Goldfarb (Hunter College, New York USA)
"FHFs control neuronal excitability through modulation of voltage-gated sodium channels" |
| 9:00 pm - 9:30 pm | General Discussion |
| 9:30 pm | Informal Poster Session |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Transcriptional Regulation of Oligodendrocyte Development |
| Discussion Leader: Vittorio Gallo (Children's National Medical Center, Washington, D.C. USA) |
| 9:00 am - 9:10 am | Introductory remarks: Vittorio Gallo |
| 9:10 am - 9:30 am | David Rowitch (Harvard Medical School, Cambridge, Massachusetts USA)
"Transcriptional Regulation of Oligodendrocytes During Development and in Disease" |
| 9:30 am - 10:00 am | General Discussion |
| 10:00 am | Coffee Break |
| 10:20 am - 10:40 am | Vittorio Gallo (Children's National Medical Center, Washington, D.C. USA)
"Identification of Sox17 as a transcription factor that regulates oligodendrocyte development" |
| 10:40 am - 11:00 am | Regina Armstrong (Uniformed Services University of the Health Sciences, Bethesda, Maryland USA)
"Musashi1 RNA-binding Protein Regulates Oligodendrocyte Lineage Development" |
| 11:00 am - 11:30 am | General Discussion |
| 11:30 am - 11:50 am | Patrizia Casaccia-Bonnefil (Robert Wood Johnson Medical School, New Brunswick, New Jersey USA)
"Histone deacetylases in the oligodendrocyte lineage" |
| 11:50 am - 12:10 pm | Gabriel Corfas (Children's Hospital of Boston, Massachusetts USA)
"erbB receptor signaling and the mechanisms of myelination" |
| 12:10 pm - 12:30 pm | General Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Model Systems: Invertebrate and Vertebrate Myelin Formation |
| Discussion Leader: David Colman (Montreal Neurological Institute at McGill University, Montreal, Canada) |
| 7:30 pm - 7:40 pm | Introductory remarks: David Colman |
| 7:40 pm - 8:00 pm | Bruce Appel (Vanderbilt University, Nashville, Tennessee USA)
"Regulation of oligodendrocyte number, distribution and differentiation in zebrafish" |
| 8:00 pm - 8:20 pm | Betty Roots (University of Toronto, Toronto, Canada)
"Myelin in Invertebrates - an Overview" |
| 8:20 pm - 8:40 pm | Will Talbot (Stanford University, Stanford, California USA)
"Genetic dissection of glial development and myelination in zebrafish" |
| 8:40 pm - 9:00 pm | Petra Lenz (University of Hawaii, Manoa, Hawaii USA)
"Myelin evolution, form and function in copepods" |
| 9:00 pm - 9:20 pm | Dan Hartline (University of Hawaii, Manoa, Hawaii USA)
"Physiology of myelinated axons in invertebrates" |
| 9:20 pm - 9:30 pm | General Discussion |
| 9:30 pm | Informal Poster Session |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Origin and Dispersal of Myelinating Cells |
| Discussion Leaders: Bill Richardson (Wolfson Institute for Biomedical Research - University College London, UK) & Boris Zalc (Hopital de la Salpetriere, Paris, France) |
| 9:00 am - 9:10 am | Introductory remarks: Bill Richardson |
| 9:10 am - 9:30 am | Richard Lu (Dana-Farber Cancer Institute, Boston, Massachusetts USA)
"Cortical glial development regulated by bHLH Olig" |
| 9:30 am - 10:00 am | General Discussion |
| 10:00 am | Coffee Break |
| 10:20 am - 10:40 am | Nicoletta Kessaris (Wolfson Institute for Biomedical Research - University College London, UK)
"Mapping the origins of oligodendrocytes in the CNS" |
| 10:40 am - 11:00 am | Mensheng Qui (Kentucky Spinal Cord Injury Research Center, University of Louisville, Kentucky USA)
"Shh-independent generation of oligodendrocytes from dorsal neural tube" |
| 11:00 am - 11:20 am | Katsuhiko Ono (National Institute of Physiological Sciences, Okazaki, Japan)
"Lineage analysis of the Olig2 expressing cells in the central nervous system" |
| 11:20 am - 11:40 am | Anne Baron-Van Evercooren (INSERM, Salpetriere, Paris, France)
"Mobilization of adult neural stem cells in the demyelinated brain: from rodent to man" |
| 11:40 am - 12:00 pm | James Goldman (Columbia University Medical Center, New York, NY USA)
"Cellular origins of oligodendrocytes in the forebrain: Coordination of migration, proliferation, and differentiation" |
| 12:00 pm - 12:30 pm | General Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
| 7:30 pm - 9:30 pm | Oligodendrocyte Signaling |
| Discussion Leader: Ben Barres (Stanford University, Stanford, California USA) |
| 7:30 pm - 7:40 pm | Introductory remarks: Ben Barres |
| 7:40 pm - 8:00 pm | Klaus-Armin Nave (Max-Planck-Institute for Experimental Medicine, Goettingen, Germany)
"Axonal control of myelination by neuregulin-1: thresholds and barriers" |
| 8:00 pm - 8:20 pm | Trent Watkins (Stanford University, Stanford, California USA)
"Time-lapse microscopy reveals a distinct, regulated transition to the myelinating oligodendrocyte phenotype" |
| 8:20 pm - 8:40 pm | Sha Mi (Biogen idec, Cambridge, Massachusetts USA)
"LINGO-1 negatively regulates oligodendrocyte differentiation and myelination" |
| 8:40 pm - 9:00 pm | Wendy Macklin (Cleveland Clinic Foundation, Cleveland Ohio USA)
"Akt pathways regulating myelination, or how to force an oligodendrocyte to myelinate" |
| 9:00 pm - 9:30 pm | General Discussion |
| 9:30 pm | Informal Poster Session |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Translating Myelin Biology to Disease Models and Patients |
| Discussion Leaders: Rick Rudick (Cleveland Clinic Foundation, Cleveland, Ohio USA) & Peter Calabresi (Johns Hopkins University, Baltimore, Maryland USA) |
| 9:00 am - 9:10 am | Introductory remarks: Rick Rudick |
| 9:10 am - 9:30 am | Moses Rodriguez (Mayo Clinic College of Medicine, Rochester, Minnesota USA)
"Recombinant human autoantibodies to oligodendrocytes as an approach to remyelination" |
| 9:30 am - 9:45 am | Discussion |
| 9:45 am - 10:05 am | Susumu Mori (Johns Hopkins University, Baltimore, Maryland USA)
"Non-invasive imaging of white matter tracts and myelination status by MRI and diffusion tensor imaging" |
| 10:05 am - 10:20 am | Discussion |
| 10:20 am - 10:40 am | Coffee Break |
| 10:40 am - 11:00 am | Michael Phillips (Cleveland Clinic Foundation, Cleveland, Ohio USA)
"MR Measures of Pathway Integrity and Function in MS" |
| 11:00 am - 11:15 am | Discussion |
| 11:15 am - 11:35 am | Gilmore O'Neill (Biogen idec, Cambridge, Massachusetts USA)
"Myelin Repair: An Industry Perspective" |
| 11:35 am - 11:55 am | Peter Calabresi (Johns Hopkins University, Baltimore, Maryland USA)
"Animal Models: Can we discriminate the effects of myelin loss from axonopathy?" |
| 11:55 am - 12:30 pm | General Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Genes: Dreams and Reality in Myelin |
| Discussion Leaders: Tony Campagnoni (UCLA, Los Angeles, California USA) & Rashmi Bansal (University of Connecticut, Farmington, Connecticut USA) |
| 7:30 pm - 7:40 pm | Introductory Remarks: Tony Campagnoni |
| 7:40 pm - 9:30 pm | Panel Discussion Featuring: |
| Peter Brophy (University of Edinburgh, Edinburgh, Scotland) |
| Monique Dubois-Dalcq (NINDS, Bethesda, Maryland, USA) |
| Steve Pfeiffer (University of Connecticut, Farmington, Connecticut USA) |
| Ueli Suter (Swiss Federal Institute of Technology, Zurich, Switzerland) |
| 9:30 pm | Informal Poster Session |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
