Saturday |
1:30 pm - 4:30 pm | Arrival and Check-in |
3:00 pm - 3:15 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:15 pm - 4:00 pm | Keynote Session: Remyelination Therapeutics |
| Discussion Leaders: Greg Duncan (University of British Columbia, Canada) and David Gonsalvez (University of Melbourne, Australia) |
3:15 pm - 3:45 pm | Jonah Chan (University of California, San Francisco, USA) "Do Remyelination Therapies Prevent Axonal Degeneration After Inflammatory Demyelination?" |
3:45 pm - 4:00 pm | Discussion |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | New Insights into Myelination and Myelin Dynamics |
| Discussion Leaders: Marc Ford (University College London, United Kingdom) and David Lyons (University of Edinburgh, United Kingdom) |
5:30 pm - 5:50 pm | Lorena Arancibia-Carcamo (University College London, United Kingdom) "The Size of the Node of Ranvier in Health and Disease" |
5:50 pm - 6:00 pm | Discussion |
6:00 pm - 6:20 pm | Sonia Mayoral (University of California, San Francisco, USA) "A GPCR Screen Identifies a Novel Role for the Kappa-Opioid Receptor in Promoting Myelination" |
6:20 pm - 6:30 pm | Discussion |
6:30 pm - 6:50 pm | Amy Herbert (Washington University in St. Louis, USA) "A Forward Genetics Approach to Understand the Molecular Mechanisms of Myelination" |
6:50 pm - 7:00 pm | Discussion |
7:00 pm - 7:20 pm | Sueli Marques (Karolinska Institutet, Sweden) "Oligodendrocyte Heterogeneity in the Mouse Central Nervous System" |
7:20 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
Sunday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Regeneration and Repair of Myelin |
| Discussion Leaders: Andrew Caprariello (University of Calgary, Canada) and Alison Lloyd (MRC Laboratory for Molecular Cell Biology, University College London, United Kingdom) |
9:00 am - 9:20 am | Valerie Brugger (University of Fribourg, Switzerland) "Functions of Histone Deacetylases in Schwann Cells During Regeneration" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Jessica Fletcher (University of Melbourne, Australia) "TrkB Activation Promotes Myelin Repair in the Brain Following Cuprizone Demyelination" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Jennifer Orthmann-Murphy (Johns Hopkins University School of Medicine, USA) "In Vivo Imaging of Cortical Demyelination and Remyelination" |
10:20 am - 10:30 am | Discussion |
10:30 am - 10:50 am | Yvonne Dombrowski (Queen's University Belfast, United Kingdom) "Regulatory T Cells Are Required for Oligodendrocyte Differentiation in Demyelinated CNS Lesions In Vivo" |
10:50 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:30 pm | Novel Approaches to Myelin Therapeutics |
| Discussion Leaders: Stephen Fancy (University of California, San Francisco, USA) and Tracy Yuen (Genentech, Inc., USA) |
1:30 pm - 1:50 pm | Stefanie Giera (Boston Children's Hospital / Harvard Medical School, USA) "The Role of GPR56 and Its Ligand in Remyelination" |
1:50 pm - 2:00 pm | Discussion |
2:00 pm - 2:20 pm | Meredith Hartley (Oregon Health and Science University, USA) "Thyroid Hormone Mimetics as a Therapeutic Strategy for Demyelinating Diseases" |
2:20 pm - 2:30 pm | Discussion |
2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
3:00 pm | Seminar Concludes |