Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Translational Research for Myelin Disorders: Imaging Leads the Way
Discussion Leaders: Jason Plemel (University of Calgary, Canada) and Fernanda Coelho (Vollum Institute, Oregon Health and Science University, USA)
3:45 pm - 4:25 pm
Mikael Simons (Technical University of Munich, Germany)
"Myelin Biogenesis and Repair"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Myelin Plasticity over Time: Development and Adaptations with Aging
Discussion Leaders: Tracy Yuen (Genentech, Inc., USA) and Ethan Hughes (University of Colorado School of Medicine, USA)
7:30 pm - 7:50 pm
David Gonsalvez (The University of Melbourne, Australia)
"Novel Insights into the Mode of Oligodendrocyte Production During Development"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Alerie Guzman de la Fuente (University of Cambridge, United Kingdom)
"Changes in the Oligodendrocyte Progenitor Cell Proteome with Ageing"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Khalil Rawji (University of Calgary, Canada)
"Rejuvenating Macrophages/Microglia for Remyelination in the Aging Central Nervous System"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Dylan Verden (University of Colorado Anschutz Medical Campus, USA)
"Role of Nrf2 in Oligodendrocyte Development and Ischemic Response"
9:20 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Myelin in Space: Cell-Intrinsic Drivers of Structure and Function
Discussion Leaders: Brad Zuchero (Stanford University, USA) and Meng-meng Fu (Stanford University, USA)
9:00 am - 9:20 am
Jenea Bin (University of Edinburgh, United Kingdom)
"Importin-13 Is a Novel Regulator of Axon Caliber Growth and Myelination"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Aiman Saab (University of Zurich, Switzerland)
"Activity-Dependent Metabolic Support to Myelinated Axons"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Elizabeth Fogarty (University of Michigan, USA)
"Investigating the Transcription Factor SOX10s Role in Regulating Promoter Use in Schwann Cells"
10:20 am - 10:30 am
Discussion
10:30 am - 10:50 am
Diane Nakamura (Montreal Neurological Institute, McGill University, Canada)
"Regulation of Mitochondrial Dynamics in Oligodendrocytes"
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Myelin in Space: Interacting with the Extracellular Environment
Discussion Leaders: Ragnhildur Karadottir (University of Cambridge, United Kingdom) and Cody Call (Johns Hopkins University, USA)
1:30 pm - 1:45 pm
Laura Fontenas (University of Virginia, USA)
"Glial Cell Interactions Across the Motor Exit Point Transition Zone"
1:45 pm - 1:50 pm
Discussion
1:50 pm - 2:05 pm
Nicolas Snaidero (Technical University of Munich, Germany)
"Structural and Functional Alterations of Projection Neurons in a Model of Cortical Multiple Sclerosis"
2:05 pm - 2:10 pm
Discussion
2:10 pm - 2:25 pm
Crystal McClain (University of Colorado Anschutz Medical Campus, USA)
"Dynamics of Demyelination in a Novel Antibody-Mediated Animal Model"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes