Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm
Keynote Session: The Cell Biology of Myelination in Health and Disease
Discussion Leader: Jessica Fletcher (University of Tasmania, Australia)
3:15 pm - 3:45 pm
Charles ffrench-Constant (University of East Anglia, United Kingdom)
"From Smart Wiring to MS: The Cell Biology of Myelination in Health and Disease"
3:45 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Molecular Mechanisms of Myelination and Remyelination
Discussion Leaders: Marie Bechler (SUNY Upstate Medical University, United States) and Themistoklis Tsarouchas (University of Edinburgh, United Kingdom)
5:30 pm - 5:45 pm
Hannah Collins (Vollum Institute - Oregon Health and Science University, United States)
"Exploring Fbxw7 Regulation of Myrf in CNS Myelination"
5:45 pm - 5:50 pm
Discussion
5:50 pm - 6:05 pm
Sophie Siems (MPI for Multidisciplinary Sciences, Germany)
"Role of Clathrin-Mediated Endocytosis in Myelinating Oligodendrocytes"
6:05 pm - 6:10 pm
Discussion
6:10 pm - 6:25 pm
Ved Topkar (Stanford University, United States)
"Structural and Sequence Determinants of mRNA Localization in Oligodendrocytes"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
Daniel Radecki (University of Wisconsin - Madison, United States)
"TGFß1-Gpnmb Signaling Inhibits oligodendrogenesis From Adult Neural Stem Cells Following Demyelination"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:05 pm
Civia Chen (University of Cambridge, United Kingdom)
"Injury-Induced Upregulation of Fibronectin and BMP4 Modulates the Differentiation of Oligodendrocyte Progenitor Cells into Schwann Cells"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
Husniye Kantarci (Stanford University, United States)
"Schwann Cells Promote Sensory Neuron Excitability"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Myelin Dysregulation and Regeneration / Mentorship Component
Discussion Leaders: Boaz Barak (Tel Aviv University, Israel) and Tania Quintela Lopez (University College London, United Kingdom)
9:00 am - 9:15 am
James Cooper (University at Buffalo, Jacobs School of Medicine and Biomedical Sciences, United States)
"Poor Remyelination of Large Lesions is Attributable to Failed Oligodendrocyte Progenitor Cell Recruitment"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Miguel Marin (UCLA, United States)
"With a View Towards Post White Matter Stroke Myelin Repair: Measuring Oligodendrogenesis and Remyelination After Motor Learning-Based Rehabilitation"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Shahrnaz Kemal (NIH / NINDS, United States)
"TPPP Dynamics in Oligodendrocytes in Health and Disease"
9:55 am - 10:00 am
Discussion
10:00 am - 10:40 am
Panel Discussion
Mentorship Component: Careers Outside Academia
Walter Kostich (National MS Society, United States)
Tim Spencer (Journal of Cell Biology, United States)
Lynette Foo (F. Hoffman-La Roche, Switzerland)
10:40 am - 11:00 am
General Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Cell-Cell Interactions Along Myelinated Axons
Discussion Leaders: Mohit Dubey (Netherlands Institute for Neuroscience, The Netherlands) and Dorien Maas (Institute of Psychiatry and Neuroscience of Paris, France)
1:30 pm - 1:45 pm
Jonathan Lezmy (University College London, United Kingdom)
"Control of Myelinated Axon Conduction Speed by Node of Ranvier Electrical and Structural Adaptations"
1:45 pm - 1:50 pm
Discussion
1:50 pm - 2:05 pm
Marie Mather (Rutgers University - New Jersey Medical School, United States)
"Regional Differences in Oligodendroglial Cholesterol Acquisition and Astrocyte Cholesterol Export"
2:05 pm - 2:10 pm
Discussion
2:10 pm - 2:25 pm
Niamh McNamara (University of Edinburgh, United Kingdom)
"Microglia Regulate Myelin Growth and Integrity in the Central Nervous System"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
