| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | SYSTEM BIOLOGY OF MUSCLE |
| Discussion Leader: Steven Tapscott (Fred Hutchinson Cancer Center, Seattle) |
| Keynote lecture: Anne Burke (Wesleyan University)
"Evolutionary Perspectives on Muscle Patterning" |
| Susan Mango (University of Utah)
"Whole genome analysis of foregut development" |
| Steven Tapscott (Fred Hutchinson Cancer Center, Seattle)
"Patterning of gene expression by MyoD" |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | DEVELOPMENTAL SPECIFICATION OF MUSCLE |
| Discussion Leader: Margaret Buckingham (Institut Pasteur) |
| Olivier Pourquié (Stowers Institute, Kansas City)
"New insights into vertebrate segmentation" |
| Shahragim Tajbakhsh (Institut Pasteur, Paris)
"Establishing identity and maintaining stemness character" |
| Susanne Dietrich (King's College, London) (short talk)
"Epaxial-hypaxial segregation of muscle" |
| Christophe Marcelle (LGDP, Marseille) (short talk)
"A Two Step Mechanism for Myotome Formation in Chick" |
| 10:30 am | Coffee Break |
| Charles Ordahl (UCSF)
"'quantal' events in myogenesis" |
| Krzysztof Jagla (INSERM Clermont-Ferrand)
"Coordinated development of muscles and tendons of the Drosophila leg" |
| Andrea Münsterberg (University of West Anglia) (short talk)
"MKP3/Pyst1 regulates levels of FGF signaling in the developing syndetome of chick somites" |
| Frederique Relaix (Institut Pasteur) (short talk)
"Pax3 and Pax7 in Myogenesis" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session |
| 5:30 pm - 7:30 pm | EVOLUTION OF MUSCLE |
| Discussion Leader: Michael Krause (NIH) |
| M. Krause (NIH)
"Maternal Control of MyoD Activation Regulates Myogenesis in the C. elegans Embryo" |
| V. Schmid (Institute of Zology, Basel)
"Jellyfish and the evolution of muscle" |
| A. Michelson (Harvard)
"Functional genomics of muscle development in Drosophila" |
| G. Unguez (New Mexico State University) (short talk)
"Skeletal muscle and its trans-differentiation capacity in the evolution of non-contractile tissues" |
| Renate Renkawitz (FB Biologie, Marburg) (short talk)
"Molecular and cellular analyses of myoblast fusion in Drosophila" |
| 8:00 pm | Dinner |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | HUMAN MUSCLE DISEASE |
| Discussion Leader: Kay Davies (University of Oxford) |
| Tom Rando (Stanford University)
"Modulating age-related changes of Notch signaling and satellite cell activation" |
| Elizabeth McNally (University of Chicago)
"Membrane defects in muscular dystrophy" |
| Kay Davies (University of Oxford)
"Utrophin and muscular dystrophy" |
| 10:30 am | Coffee Break |
| Gert Van Omnen (Leiden University)
"Normal and pathological myogenesis: differentiation and restoration of gene expression" |
| Jeffrey Chamberlain (University of Washington)
"Systemic delivery of genes to striated muscle using AAV" |
| Yvan Torrente (University of Milan) (short talk)
"Myogenic potential of human circulating AC133 positive stem cells" |
| Maurilio Sampaolesi (SCRI, Milan) (short talk)
"Cell therapy of primary myopathies by mesoangioblasts" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 4:45 pm | Poster Session |
| 5:30 pm - 7:30 pm | GENERATION AND REGENERATION OF MUSCLE |
| Discussion Leader: Helen Blau (Stanford University) |
| Nadia Rosenthal (EMBL, Monterondo)
"Growth factor enhancement of muscle regeneration" |
| Kenneth Poss (Duke University)
"Regulation of cardiac regeneration in zebrafish" |
| Gabrielle Kardon (Harvard Medical School)
"Developmental origin of muscle progenitors" |
| Stefano Schiaffino (Venetian Institute of Molecular Medicine)
"NFAT and FOXO signaling in skeletal muscle" |
| 8:00 pm | Dinner |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | MYOGENIC STEM CELLS |
| Discussion Leader: Giulio Cossu (SCRI, Milan) |
| Michael Rudnicki (Ottawa Health Research Institute)
"Molecular mechanisms regulating regenerative myogenesis" |
| Helen Blau (Stanford University)
"Bone marrow to muscle" |
| 10:00 am | Coffee Break |
| Terence Partidge (MRC, Hammersmith Hospital, London)
"The muscle satellite cell as a stem cell" |
| Johnny Huard (University of Pittsburgh)
"Gene therapy & tissue engineering based on muscle stem cells: potential for tissue regeneration" |
| Margaret Buckingham (Istitut Pasteur, Paris) (short talk)
"Cells in the dorsal aorta and in skeletal muscle of the myotome share a common origin" |
| Naohiro Hashimoto (Mitsubishi Kagaku Institute, Tokyo) (short talk)
"Human myogenic progenitor cells retain both myogenic and osteogenic properties" |
| 12:30 pm | Lunch |
| 1:30 pm - 5:00 pm | Free Time (visit to Lucca) |
| 5:30 pm - 7:30 pm | SPECIFICATION OF CARDIAC AND SMOOTH MUSCLE |
| Discussion Leader: Steven Hauschka (Washington University, Seattle) |
| Brian Black (UCSF) (short talk)
"Transcriptional regulation of mef2c in the anterior/secondary heart field" |
| Richard Harvey (V. Chang Cardiac Research Institute)
"Transcription factors in heart development and congenital heart disease" |
| Robert Schwartz (Baylor College, Houston)
"Myogenic Gene Switch: Differential Phosphorylation of SRF MADS Box" |
| Steven Hauschka (Washington University, Seattle) (short talk) |
| Rolf Bodmer (University of Michigan)
"Genetics of cardiac development and aging" |
| 8:00 pm | Dinner |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | SIGNAL TRANSDUCTION AND PLASTICITY |
| Discussion Leader: Nadia Rosenthal (EMBL, Monterondo) |
| Grace Pavlath (Emory University)
"Regulation of Myogenesis by Sca-1" |
| Leslie Leinwald (University of Colorado)
"Myosin mutations and skeletal myopathies" |
| 10:00 am | Coffee Break |
| Giovanna Marazzi (Mount Sinai Medical School)
"Cytokine and p53 stress pathways in stem cell allocation?" |
| Brad Olwin (University of Colorado)
"Satellite cell activation from the outside in" |
| Peter Currie (Victor Chang Cardiac Research Institute)
"Genetic control of embryonic slow twitch muscle morphogenesis in zebrafish" |
| Eyal Bengal (Technion-Israel Institute of Technology) (short talk)
"The p38 MAPK pathway regulates muscle cell fate during early Xenopus laevis development" |
| John Mc Dermott (York University, Toronto) (short talk)
"Regulation of MEF2 activity and stability by targeted phoshorylation" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session |
| 7:30 pm - 9:30 pm | TRANSCRIPTIONAL REGULATION |
| Discussion Leader: Steven Tapscott (Fred Hutchinson Cancer Center, Seattle) |
| Vittorio Sartorelli (NIH)
"Role of Polycomb Proteins in Regulating Skeletal Muscle Differentiation" |
| Charles Emerson (Boston Biomedical Research Institute)
"Genetic control of somite patterning for Myf5 regulation" |
| Pier Lorenzo Puri (Salk Institute)
"Regulation of muscle transcriptosome assembly and activity by extra-cellular cues" |
| Peter Rigby (Institute of Cancer Research, London)
"Transcriptional regulation of the mrf4/myf5 locus" |
| 8:00 pm | Dinner |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
