Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:15 pm - 4:00 pm
Keynote Session: Unlocking the Mysteries of Stem Cell Quiescence
Discussion Leader: Jesus Castor-Macias (University of Michigan, United States)
3:15 pm - 3:55 pm
Thomas Rando (University of California, Los Angeles, United States)
"Unlocking the Mysteries of Stem Cell Quiescence"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Recent Advances in Technology & Biological Models
Discussion Leader: Pauline Garcia (INMG, France)
5:30 pm - 5:45 pm
Erik Jacques (University of Toronto, Canada)
"In Silico Predictions Coupled with Mini-IDLE Identifies Myofiber-derived Biomolecules Dictating Muscle Stem Cell Quiescence"
5:45 pm - 5:50 pm
Discussion
5:50 pm - 6:05 pm
Kodey Silknitter (University of Maine, United States)
"Investigating the Role of B4gat1 as a Facilitator of Axon Guidance and Muscle Development"
6:05 pm - 6:10 pm
Discussion
6:10 pm - 6:25 pm
Xhem Qabrati (ETH Zürich, Switzerland)
"Transgene-Free Direct Conversion of Fibroblasts into Functional Muscle Stem Cells Utilizing Synthetic mRNA and Small Molecules"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
Charline Jomard (CNRS 5261 Gondin INGM, France)
"Sex Differences in Skeletal Muscle Regeneration in a Mouse Model of Lengthening Contraction-induced Injury"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:05 pm
Yoann Le Toquin (Mechanisms in integrated Life Sciences - INMG - Lyon - France, France)
"Myoblast Nematic Behavior: From Collective Motion to Fusion"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
Valentina Maria Lionello (University College London, United Kingdom)
"Modelling X-linked Centronuclear Myopathy Using Advanced Human Skeletal Muscle Models"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Novel Players in Skeletal Muscle Development, Disease & Aging
Discussion Leader: Jeffrey Kelu (King's College London, United Kingdom)
9:00 am - 9:15 am
Yang Li (The Chinese University of Hong Kong, Hong Kong SAR China)
"Yin Yang 1 Deficiency in Skeletal Muscle Stem Cell Aggravates Muscle Fibrosis in Duchenne Muscular Dystrophy Mouse by Disrupting Muscle Stem Cell/Macrophage/Fibro-adipogenic Progenitor Crosstalk"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Quentin Sastourné-Arrey (OHRI, Canada)
"Role of Hyaluronic Acid Synthase 2 in the Activation of Skeletal Muscle Satellite Cells"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Sarah Nahlé (Montreal Clinical Research institute (IRCM), Canada)
"Evidence of Fusogene-based Myocyte Diversity During Embryonic Myogenesis in the Mouse"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Lola Lessard (PGNM-INMG, France)
"Metabolic Plasticity Defects as a Potential Therapeutic Target in Type I Myotonic Dystrophy"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Elena Monti (Stanford University, United States)
"Rejuvenating Aged Skeletal Muscle by Targeting a Gerozyme"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Léa Castellano (INMG, PGNM, France)
"NuMA1 Promotes Microtubule Organisation and Controls Myonuclear Dynamics in Skeletal Muscle"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Job Opportunities for Early Career Scientists
Discussion Leader: Zachary Hettinger (Harvard Medical School, United States)
1:30 pm - 2:30 pm
Panel Discussion
Job Opportunities for Early Career Scientists
Thomas Rando (University of California, Los Angeles, United States)
Mary Baylies (Memorial Sloan Kettering Cancer Center, United States)
Antonio Filareto (Boehringer Ingelheim Pharmaceuticals, Inc., United States)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes
