Sunday |
2:00 pm - 8:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Cancer: Viruses and Signaling |
| Discussion Leader: Alan Rickinson (University of Birmingham, United Kingdom) |
7:40 pm - 7:45 pm | Introduction by Discussion Leader |
7:45 pm - 8:25 pm | Harald zur Hausen (German Cancer Research Center, Germany) "Discovery and Early Studies of EBV in Burkitt's Lymphoma and NPC" |
8:25 pm - 8:40 pm | Discussion |
8:40 pm - 9:20 pm | Hans Clevers (Hubrecht Institute, The Netherlands) "Wnt Signaling and Cancer" |
9:20 pm - 9:30 pm | Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Cancer Genomics |
| Discussion Leader: Yu Sun Chang (Chang Gung University, Taiwan) |
9:00 am - 9:05 am | Introduction by Discussion Leader |
9:05 am - 9:45 am | Andrew Futreal (University of Texas MD Anderson Cancer Center, USA) "Cancer Genomics and Evolution" |
9:45 am - 10:05 am | Discussion |
10:05 am - 10:30 am | Group Photo / Coffee Break |
10:30 am - 10:50 am | Jin-Xin Bei (Sun Yat-Sen University Cancer Center, China) "Genetic Basis of Nasopharyngeal Carcinoma" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Hong Zheng (The University of Hong Kong, Hong Kong SAR China) "Identification of Genetic Susceptibility Genes in Nasopharyngeal Carcinoma by Next-Generation Sequencing" |
11:20 am - 11:30 am | Discussion |
11:30 am - 12:10 pm | Kwok Wai Lo (The Chinese University of Hong Kong, Hong Kong SAR China) "NPC Genetics: Progressive Genomic Changes" |
12:10 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
3:00 pm - 4:00 pm | Power Hour |
| The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring. |
| Organizers: Fei-Fei Liu (Princess Margaret Hospital, Canada) and Anne Lee (The University of Hong Kong, Hong Kong SAR China) |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Lessons from an Epithelial Cancer |
| Discussion Leader: Ingemar Ernberg (Karolinska Institute, Sweden) |
7:30 pm - 7:35 pm | Introduction by Discussion Leader |
7:35 pm - 8:15 pm | Elaine Fuchs (The Rockefeller University, USA) "Transition of Normal Epithelia to Cancer" |
8:15 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | Mu Sheng Zeng (Sun Yat-Sen University Cancer Center, China) "NPC, an Epithelial Cancer: Immortalization and Tumorigenesis" |
9:15 pm - 9:30 pm | Discussion |
Tuesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | EBV Genetics and Biology |
| Discussion Leader: Lori Frappier (University of Toronto, Canada) |
9:00 am - 9:05 am | Introduction by Discussion Leader |
9:05 am - 9:45 am | Henri-Jacques Delecluse (DKFZ - German Cancer Research Center, Germany) "Is NPC Caused by a Particular EBV?" |
9:45 am - 10:05 am | Discussion |
10:05 am - 10:30 am | Coffee Break |
10:30 am - 11:10 am | Richard Longnecker (Northwestern University, USA) "EBV Entry into Host" |
11:10 am - 11:30 am | Discussion |
11:30 am - 12:10 pm | George Tsao (University of Hong Kong, Hong Kong SAR China) "Establishment of New NPC Xenografts and Cell Lines for EBV Studies" |
12:10 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
2:00 pm - 4:00 pm | Poster Session |
4:00 pm - 6:00 pm | Risk Factors and Cancer |
| Discussion Leader: Eric Stanbridge (University of California, Irvine, USA) |
4:00 pm - 4:05 pm | Introduction by Discussion Leader |
4:05 pm - 4:45 pm | Xin Lu (Ludwig Institute for Cancer Research, United Kingdom) "p53, a Key Regulator of Genomic Stability in Cancer" |
4:45 pm - 5:05 pm | Discussion |
5:05 pm - 5:45 pm | Allan Hildesheim (National Cancer Institute, NIH, USA) "Use of Viral and Genetic Markers for Risk Stratification for Development of Screening Programs for the Early Detection of NPC" |
5:45 pm - 6:00 pm | Discussion |
6:00 pm | Dinner |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | NPC Diagnostic Biomarkers |
| Discussion Leader: Pierre Busson (Institut Gustave Roussy, France) |
9:00 am - 9:05 am | Introduction by Discussion Leader |
9:05 am - 9:45 am | Fei-Fei Liu (Princess Margaret Hospital, Canada) "Prognostic Significance of miRNA Signatures for Detection of Metastatic NPC" |
9:45 am - 10:05 am | Discussion |
10:05 am - 10:25 am | Honglin Chen (University of Hong Kong, Hong Kong SAR China) "EBV BART miRNA and Serological Biomarkers for NPC" |
10:25 am - 10:35 am | Discussion |
10:35 am - 11:00 am | Coffee Break |
11:00 am - 11:40 am | Dennis Lo (Chinese University of Hong Kong, Hong Kong SAR China) "Plasma DNA Analysis for Detecting NPC: Biological Insights and Clinical Applications" |
11:40 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Wei Dai (The University of Hong Kong, Hong Kong SAR China) "Methylation Biomarkers in NPC" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | Challenges for Primary Treatment of NPC |
| Discussion Leader: Anne Lee (The University of Hong Kong, Hong Kong SAR China) |
7:30 pm - 7:35 pm | Introduction by Discussion Leader |
7:35 pm - 8:10 pm | Brian O'Sullivan (University of Toronto, Canada) "Challenges for Radiotherapy Treatment of NPC" |
8:10 pm - 8:20 pm | Discussion |
8:20 pm - 8:45 pm | Roger Ngan (Queen Elizabeth Hospital, Hong Kong SAR China) "Evolution of NPC Clinical Trials in Hong Kong" |
8:45 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Jun Ma (Sun Yat-Sen Medical University, China) "NPC Clinical Trials in Guangzhou" |
9:20 pm - 9:30 pm | Discussion |
Thursday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Innovative Therapies for NPC / Selected Poster Presentations |
| Discussion Leader: Rajiv Khanna (QIMR Berghofer Medical Research Institute, Australia) |
9:00 am - 9:05 am | Introduction by Discussion Leader |
9:05 am - 9:45 am | Cliona Rooney (Baylor College of Medicine, USA) "Cancer Immunotherapy and Challenges for NPC" |
9:45 am - 10:05 am | Discussion |
10:05 am - 10:30 am | Brigette Ma (Chinese University of Hong Kong, Hong Kong SAR China) "Novel Targets for NPC Treatment" |
10:30 am - 10:40 am | Discussion |
10:40 am - 11:10 am | Coffee Break |
11:10 am - 11:35 am | William Wei (Hong Kong Sanatorium & Hospital, Hong Kong SAR China) "Challenges for Surgical Management of Recurrent NPC" |
11:35 am - 11:45 am | Discussion |
11:45 am - 11:55 am | Raymond Ng (University of Toronto, Canada) "Detection and Screening for NPC with Trans-Oral Brushing and Determination of EBV DNA" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Troy Messick (The Wistar Institute, USA) "Development of Small Molecule Inhibitors of EBNA1 for the Treatment of Nasopharyngeal Carcinoma" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Mhairi Morris (Faculty of Health and Life Sciences, De Montfort University, United Kingdom) "EBV-Encoded LMP1 Induces a Myofibroblast-Like Phenotype in Epithelial Cells via Epithelial-to-Mesenchymal Transition" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Future Prospects for NPC |
| Discussion Leader: Lawrence Young (University of Warwick, United Kingdom) |
4:00 pm - 4:10 pm | Introduction by Discussion Leader |
4:10 pm - 4:50 pm | Alan Rickinson (University of Birmingham, United Kingdom) "Future Focus for Basic NPC and EBV Studies" |
4:50 pm - 5:05 pm | Discussion |
5:05 pm - 5:45 pm | Quynh Le (Stanford University, USA) "Future Personalised Clinical Care for NPC Patients" |
5:45 pm - 6:00 pm | Discussion |
6:00 pm | Dinner |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |