Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Structural Biology and Natural Product Biosynthesis
Discussion Leader: Constance Bailey (Lawrence Berkeley National Laboratory, USA)
3:45 pm - 4:20 pm
Janet Smith (University of Michigan, USA)
"Synthesis of Branched Starter Units by Polyketide Synthase Loading Modules"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Understanding the Function and Bioactivity of Natural Products
Discussion Leaders: Taylor Hari (University of Ottawa, Canada) and Robert Ziegler (Massachusetts Institute of Technology, USA)
7:30 pm - 7:45 pm
Nagasandhya Guntaka (University of Florida, USA)
"A Structural Biology Approach Reveals Key Aspects in Colibactin Biosynthesis and Mechanism of Microbiome-Associated Action"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Andrew Gasparrini (Washington University in St. Louis, USA)
"Characterization and Inhibition of Emerging Tetracycline Resistance Enzymes"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Laura Mike (University of Michigan, USA)
"Discovery of Nicoyamycin A, an Inhibitor of Uropathogenic Escherichia coli Growth in Low Iron Environments"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
David Fazakerley (Aberystwyth University, United Kingdom)
"Potent Bioactive Naphthoquinone Discovered in Problematic Invasive Weed"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Mary Egbuta (Southern Cross University, Australia)
"Bioactive Volatiles Extracted from Cotton Waste Products"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:30 pm
General Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Accessing New Scaffolds: Chemistry and Biosynthesis
Discussion Leaders: Fan Liu (Harvard University, USA) and Graham Heberlig (University of Ottawa, Canada)
9:00 am - 9:15 am
Bethany Okada (Princeton University, USA)
"Natural Product Discovery in Burkholderia thailandensis Through Cryptic Gene Cluster Activation"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Kwo-Kwang Wang (University of Illinois at Urbana-Champaign, USA)
"Investigating the Biosynthesis of Fosfazinomycin, a Natural Product Containing a Unique Hydrazide Linkage"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Masha Elkin (Yale University, USA)
"Total Synthesis of (±)-Berkeleyone A"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Patrick Dobrounig (Graz University of Technology, Austria)
"Synthesis of an Amphiphilic Oligoaryl-Based ApoA1 Mimetic"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Eric Welin (California Institute of Technology, USA)
"Asymmetric Total Synthesis of (-)-Jorumycin"
10:35 am - 10:40 am
Discussion
10:40 am - 11:00 am
General Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Breakout Sessions
Rather than a traditional panel discussion, this session will allow attendees to rotate through small, informal breakout sessions with the invited career mentors, to hear their insights on professional development and career planning.
Discussion Leader: Michelle Goettge (University of Illinois, USA)
1:30 pm - 2:30 pm
Panel Discussion
Careers in Natural Products Chemistry and Biology
James Leahy (University of South Florida, USA)
Anne Osbourn (John Innes Centre, United Kingdom)
Joshua Pierce (North Carolina State University, USA)
Elaine Lee (Vertex Pharmaceuticals, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
