Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Natural Product Discovery
Discussion Leader: Tony Davis (University of California, San Diego, USA)
3:45 pm - 4:20 pm
Yi Tang (University of California, Los Angeles, USA)
"Target-Guided Genome Mining of Natural Products"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Natural Product Biosynthesis and Bioactivity
Discussion Leaders: Michelle Goettge (Manus Biosynthesis, USA) and Simon Moore (Imperial College London, United Kingdom)
7:30 pm - 7:45 pm
Jack Ganley (Duke University, USA)
"Investigation of Mosquito-Microbiome Natural Products"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
XiaoRui Guo (University of Illinois at Urbana-Champaign, USA)
"Natural Product Discovery via Reactivity-Based Screening"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Linna An (University of Illinois at Urbana-Champaign, USA)
"Substrate-Assisted Enzymatic Formation of Lysinoalanine in Duramycin"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Elizabeth Meier (Achaogen, USA)
"Delineating the Late Steps of Gentamicin and Sisomicin Biosynthesis"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Zdenek Kamenik (Institute of Microbiology, Czech Academy of Sciences, Czech Republic)
"Lincosamide Antibiotics: Structural Simplicity Contrasts with Biosynthetic Complexity and Combinatorial Biosynthesis Opportunities"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Laurence Maschio (University of Bristol, United Kingdom)
"Engineering the Abyssomicin C Biosynthetic Pathway to Produce Functionally Optimised 'Unnatural' Natural Products"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Synthetic Strategies for Complex Molecules
Discussion Leaders: Jana Markley (Washington University in St. Louis, USA) and Anthony Fatino (Kansas State University, USA)
9:00 am - 9:15 am
Davide Deodato (New York University Abu Dhabi, United Arab Emirates)
"Photocaged Morpholino Oligonucleotides: Synthesis, (Photo)chemical Evaluation and Application in Developmental Biology"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Jennifer Walters (Temple University, USA)
"(Poly)cationic Iodane (III) Mediated Oxidative Ring Expansion of Secondary Alcohols"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Sharon Michalak (University of California, Irvine, USA)
"Synthesis and Biological Investigations of the Haterumaimide and Lissoclimide Natural Products"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Jonathon Ryan (UNSW Sydney, Australia)
"Convergent Synthesis of the 5,3'-Linked Naphthylisoquinoline Alkaloids"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Anika Tarasewicz (University of Toronto, Canada)
"Progress Towards the Total Synthesis of Nagelamide J"
10:35 am - 10:40 am
Discussion
10:40 am - 11:00 am
General Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Development Panel
Discussion Leader: Autumn Flynn (Emory University, USA)
1:30 pm - 2:30 pm
Panel Discussion
Career Development
Danielle Dube (Bowdoin College, USA)
Matthew LaMarche (Novartis, USA)
Yi Tang (University of California, Los Angeles, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
