| SUNDAY - July 29, 2001 |
| 7:30-7:35 | WELCOME AND Tilton official |
| Discussion Leader. Frank Hauser - SUNY Albany |
| 7:35 | Cynthia Shafer - Chiron Corp.
The Total Synthesis of Bengazole A |
| 8:10 | Jim Heck - Merck Research Laboratories
Natural Products in Drug Discovery |
| 8:55 | Ernest Wenkert - Univ. California, San Diego
Seco-Steroid Model Synthesis
|
| MONDAY - July 30, 2001 |
| 8:25-8:50 | PHOTO |
| Discussion Leader. Amy Howell - Univ. of Connecticut |
| 8:55 | Michael Kort - Abbott Laboratories
Glucocorticoid Receptor Modulators as Anti-Inflammatory Agents |
| 9:30 | Denise Spero - Boehringer-Ingelheim Pharmaceuticals
The Design of Cysteine Protease Inhibitors for the Treatment of Autoimmune Diseases |
| 10:05-10:30 | COFFEE |
| Discussion Leader. Elisabeth Syage - Allergan |
| 10:30 | Robin Polt - University of Arizona (Short Talk)
Micrometalloenzymes. Use Of Bifurcated Dipeptides As Ligands For Transition Metal Mediated Catalysis.
|
| 10:55 | Daniel Kahne - Princeton University
Studies on the Natural Product Vancomycin |
| 11:50 | David Bundle - University of Alberta
Structural Basis For Neutralization Of Shiga-Like Toxins By Synthetic Multivalent Carbohydrate |
| 4:00-6:00 | POSTER SESSION 1 |
| Discussion Leader. Philip Kym - Abbott Labs |
| 7:30 | Maarten Postema - Wayne State University (Short Talk)
Synthesis of Differentially Linkedbeta-C-Disaccharides by RCM
|
| 7:50 | Chatan Khosla - Stanford University
Biosynthetic Engineering of Complex Polyketides |
| 8:40 | Sidney Hecht - University of Virginia
Bleomycin: Combinatorial Chemistry as a Means of Exploring Mechanism of Action |
| TUESDAY - July 31, 2001 |
| Discussion Leader. Timo Ovaska - Connecticut College |
| 8:45 | Stephen Dewey - Brookhaven National Laboratories
Development Of A Novel Pharmacologic Treatment For Addiction |
| 9:20 | Abimael Rodriguez - University of Puerto Rico, Rio Pedras
Novel Constituents of the Caribbean Gorgonian Octocoral Pseudopterogorgia bipinnata and Some Chemical Aspects Pertaining to their Biosynthesis |
| 10:00-10:20 | COFFEE |
| Discussion Leader. Ellen Baxter - RWJ |
| 10:20 | Christopher J Welch - Agrivir AB (Short Talk)
Plant Associated Bacteria as a Source of Antifungal Metabolites
|
| 10:40 | Ilya Raskin - Rutgers University
Novel Technologies For Natural Product Bioprospecting |
| 11:15 | Veronique Gouverneur - Oxford University
New regio- and stereocontrol using aldolase antibodies. Enantioselective route to oxygen heterocyclic rings |
| 11:50 | Alanna Schepartz - Yale University
Functional Miniature Proteins |
| 4:00-6:00 | POSTER SESSION 2 |
| Discussion Leader. Michael Luzzio - Pfizer |
| 7:30-7:45 | Richard E. Taylor - University of Notre Dame (Short Talk)
Conformation-Activity Relationships in Complex Natural Products |
| 7:50-8:35 | Lewis Mander - Australian National University
Exploitation of Benzenoid Building Blocks in the Assembly of Complex Polycyclic Natural Products |
| 8:40-9:25 | Ian Scott - Texas A&M University
Genetically Programmed Synthesis of Natural Products |
| WEDNESDAY - August 1, 2001 |
| Discussion Leader. Anthony Shuker - NuTec Sciences |
| 8:45 | Keith Woerpel - University of California at Irvine
Reactions of oxocargenium ions with nucleophiles: Stereoelectronic and electronic effects
and applications in stereoselective synthesis |
| 9:20 | Andy Evans - Indiana University
New Organometallic Mediated Cross-Coupling Reactions |
| 10:05-10:25 | COFFEE |
| Discussion Leader. Rebecca Hoye - Macalester College |
| 10:25 | Scott R. Gilbertson - Washington University
Bicyclic Phosphine-Oxazoline Ligands in the Heck Reaction, p-allylation and Conjugate Addtion |
| 10:45 | John Montgomery - Wayne State University
Nickel Catalysis: From Reaction Discovery to Complex Molecule Synthesis |
| 11:20 | David Austin - Yale University
Heteroatom-Liked Intramolecular Pauson-Khand Cyclizations: Application to the Synthesis of Palau'amine and other Guanidine Containing Natural Products |
| 11:55 | Kay Brummond - University of Pittsburgh
A New Approach to Prostaglandins: The Silicon-Tethered Pauson-Khand Reaction |
| 4:00-6:00 | POSTER SESSION 3 |
| 6:00-7:15 | Lobster Dinner |
| Discussion Leader. Frederick A. Luzzio - Univ. Louisville |
| 7:15-7:30 | GRC Site Evaluations |
| 7:30 | Matthias C. McIntosh - University of Arkansas (Short Talk)
Approaches to the Synthesis of Eleutherobin and the Eupomatilones via the Ireland Claisen Rearrangement
|
| 7:50 | Tsutomu Katsuki - Kyushu University
Asymmetric Catalysis of Metallosalen Complexes |
| 8:40-9:25 (45) | Robert Grubbs - California Institute of Technology
The development and applications of metathesis catalysts in organic synthesis |
| THURSDAY - August 2, 2001 |
| Discussion Leader. David Mootoo - Hunter College |
| 8:45 | Chafiq Hamdouchi - Eli Lilly & Co.
Total synthesis and biological evaluation of novel analogues of Papulacandins |
| 9:20 | Philip Hamann - Wyeth-Ayerst Research
Mylotarg, the first approved antibody-targeted chemotherapeutic agent |
| 10:05-10:25 | COFFEE |
| Discussion Leader. Bradford Mundy - Colby College |
| 10:20 | Gerald B. Hammond - University of Massachusetts Dartmouth (Short Talk)
Phytochemical Analysis of Peruvian Wound-Healing Plants |
| 10:40 | Felicia Etzkorn - Virginia Tech
Organic templates for elucidating the cell cycle |
| 11:15 | Marc Snapper - Boston College
Synthesis and Use of Natural Products as Probes of Biological Systems |
| 11:50 | Peter Wipf - University of Pittsburgh
Recent progress in the total synthesis of alkaloids |
| 2:00 | 50th Anniversary Softball Game - Academic All Stars vs. Industrial All Stars |
| 5:45-7:15 | 50th Anniversary Dinner |
| Discussion Leader. Robin Cooper - Cooper Associates |
| 7:15-7:30 | Softball Awards and Announcements |
| 7:30 | Peter E. Maligres - Merck Research Laboratories, Merck & Co. (Short Talk)
Stereocontrolled Preparation of a Nonpeptidal (-)-Spirobicyclic NK-1 Receptor Antagonist |
| 7:50 | Anthony Barrett - Imperial College
Recent Advances in the Synthesis of Bioactive Natural Products |
| 8:40 | Sir Jack Baldwin - Oxford University
Mechanistic and Structural Studies on Penicillin Biosynthesis |
