Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Gene Regulatory Networks
Discussion Leader: Tatjana Sauka-Spengler (University of Oxford, United Kingdom)
7:40 pm - 7:45 pm
Opening Remarks
7:45 pm - 8:10 pm
Marianne Bronner (California Institute of Technology, USA)
"Neural Crest GRN"
8:10 pm - 8:25 pm
Discussion
8:25 pm - 8:40 pm
Selected from Poster Abstracts: Ruth Williams (University of Oxford, United Kingdom)
"Genome-Wide Regulatory Profiling of Cranial Neural Crest Reveals Network of cis-Regulatory Elements and Super Enhancer-Like Clusters Controlling Neural Crest Master Regulators"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
Andrea Streit (King's College London, United Kingdom)
"Cranial Placode GRN"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Evolutionary Origins
Discussion Leader: Gerhard Schlosser (NUI Galway, Ireland)
9:00 am - 9:25 am
Lucia Manni (University of Padova, Italy)
"The Ectodermal Placodes in Tunicates and the Evolution of Secondary Sensory Cells"
9:25 am - 9:40 am
Discussion
9:40 am - 9:55 am
Selected from Poster Abstracts: Stephen Green (California Institute of Technology, USA)
"Ancient Evolutionary Origin of Vertebrate Enteric Nervous System from Trunk Neural Crest-Derived Precursors"
9:55 am - 10:05 am
Discussion
10:05 am - 10:30 am
Jr-Kai Sky Yu (Academia Sinica, Taiwan)
"Tracing the Evolutionary Origins of Neural Crest and Placodes: Insights
from the Cephalochordate Amphioxus"
10:30 am - 10:45 am
Discussion
10:45 am - 11:15 am
Coffee Break
11:15 am - 11:30 am
Selected from Poster Abstracts: Daniel Medeiros (University of Colorado Boulder, USA)
"Conserved and Divergent Functions for Endothelin Signaling in Lamprey and Gnathostomes Suggest a New Role in Patterning the Head Skeleton and Jaws"
11:30 am - 11:40 am
Discussion
11:40 am - 12:05 pm
Bernd Fritzsch (University of Iowa, USA)
"From
Placode to Hearing: Evolution and Development of the Vertebrate Ear"
12:05 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
Organizer: Marianne Bronner (California Institute of Technology, USA)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
The Border Zone and Regional Patterning
Discussion Leader: Andrew Groves (Baylor College of Medicine, USA)
7:30 pm - 7:55 pm
Jean-Pierre Saint Jeannet (New York University College of Dentistry, USA)
"Control of Placode Progenitor Formation by Retinoic Acid: A Balancing
Act"
7:55 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Selected from Poster Abstracts: Amanda Janesick (Stanford University School of Medicine, USA)
"RAR and Wnt Signaling Converge on Znf703, a Novel RA Target Which Inhibits Otic Fate and Neural Crest Induction"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Selected from Poster Abstracts: Sunita Singh (Baylor College of Medicine, USA)
"The Role of Foxi3 in the Regulation of Inner Ear Development"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
Marcos Simoes-Costa (Cornell University, USA)
"Gene Regulatory Control of Neural Crest Axial Identity and Fate"
9:15 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
EMT, Delamination and Migration
Discussion Leader: Laura Gammill (University of Minnesota, USA)
9:00 am - 9:25 am
Dominique Alfandari (University of Massachusetts, USA)
"ADAM Complex Regulation of Cranial Neural Crest Behavior: From the
Membrane to the Nucleus and Back Again"
9:25 am - 9:40 am
Discussion
9:40 am - 9:55 am
Selected from Poster Abstracts: Mary McKinney (Stowers Institute for Medical Research, USA)
"Angiopoietin-2 Signaling Plays a Critical Role in Neural Crest Cell Migration"
9:55 am - 10:05 am
Discussion
10:05 am - 10:30 am
Pablo Strobl-Mazzulla (National Scientific and Technical Research Council (CONICET), Argentina)
"Epigenetic-microRNA
Regulation Controls Neural Crest Migration"
10:30 am - 10:45 am
Discussion
10:45 am - 11:15 am
Coffee Break
11:15 am - 11:30 am
Selected from Poster Abstracts: Shuyi Nie (Georgia Institute of Technology, USA)
"Cdc42 Regulates the Cellular Localization of Cdc42ep1 in Controlling Neural Crest Cell Migration"
11:30 am - 11:40 am
Discussion
11:40 am - 12:05 pm
Anna Cariboni (University of Milan, Italy)
"From the Nasal Placode to the Brain: Different Requirements of
Semaphorins and Vascular Endothelial Growth Factor During the Development of
Mouse GnRH-Secreting Neurons"
12:05 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Morphogenesis and Tissue Interactions
Discussion Leader: Chaya Kalcheim (Hebrew University of Jerusalem, Israel)
7:30 pm - 7:55 pm
Sophie Creuzet (University of Paris-Sud, France)
"Role of the Neural Crest in Brain Development and Homoeostasis"
7:55 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Selected from Poster Abstracts: Sophie Wiszniak (Centre for Cancer Biology, Australia)
"Neural Crest Cell and Second Heart Field Interactions Orchestrate Cardiac Outflow Tract Development"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Selected from Poster Abstracts: Martin Basch (Case Western Reserve University, USA)
"Expression of Endothelins Suggests Multiple Roles in Neural Crest Contribution to the Lateral Wall of the Cochlea"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
Michelle Southard-Smith (Vanderbilt University Medical Center, USA)
"Neural Crest Lineages and Innervation of the Lower Urinary Tract"
9:15 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Cell Fate, Potential and Differentiation
Discussion Leader: Bruce Riley (Texas A&M University, USA)
9:00 am - 9:25 am
Peter Lwigale (Rice University, USA)
"Molecular Signaling During Periocular Neural Crest Cell Migration and Differentiation into Ocular Tissues"
9:25 am - 9:40 am
Discussion
9:40 am - 9:55 am
Selected from Poster Abstracts: Patrick Blader (CNRS / INSERM / Paul Sabatier University, France)
"Cranial Neural Crest Does Not Contribute Significantly to Cell-Type Heterogeneity in the Developing Zebrafish Olfactory Placode"
9:55 am - 10:00 am
Discussion
10:00 am - 10:25 am
Anthony Firulli (Indiana University School of Medicine, USA)
"Exclusion of Dlx5/6 Expression from the Distal-Most Mandibular Arches Enables BMP-Mediated Specification of the Distal Cap"
10:25 am - 10:40 am
Discussion
10:40 am - 11:10 am
Coffee Break
11:10 am - 11:25 am
Selected from Poster Abstracts: Kathryn Song Eng Cheah (The University of Hong Kong, Hong Kong SAR China)
"Impact of SOX2 Dosage on Sensory Neurogenesis and Prosensory Versus Non-Sensory Cell Fate in the Inner Ear"
11:25 am - 11:30 am
Discussion
11:30 am - 11:45 am
Selected from Poster Abstracts: Shuo Wei (University of Delaware, USA)
"A New Transgenic Xenopus Reporter Line Reveals Dynamic Expression of Snail2 During Cranial Neural Crest Development"
11:45 am - 11:50 am
Discussion
11:50 am - 12:15 pm
Marthe Howard (University of Toledo Health Science Campus, USA)
"Molecular Mechanisms of Autonomic Neuron Development"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Birth Defects
Discussion Leader: Anthony Lamantia (The George Washington University, USA)
7:30 pm - 7:55 pm
Thomas Maynard (The George Washington University, USA)
"Disrupted Development of Cranial Neural Crest and Placodes in 22Q11 Deletion
Syndrome"
7:55 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Selected from Poster Abstracts: Natalie Shaw (National Institute of Environmental Health Sciences, NIH, USA)
"Mutations in SMCHD1 Are Associated with Congenital Arhinia and Facioscapulohumeral Muscular Dystrophy Type 2"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Selected from Poster Abstracts: Celine Delloye-Bourgeois (CNRS UMR5310 / INSERM U1217 / University of Lyon, France)
"Microenvironment-Driven Tumorigenic Events Revealed by a Model Fully Replicating Neuroblastoma"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
Hela Azaiez (University of Iowa, USA)
"The Genetic Complexity of Hereditary Deafness"
9:15 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
Stem Cells and Regeneration
Discussion Leader: Paolo Forni (University at Albany, SUNY, USA)
9:00 am - 9:25 am
Shannon Davis (University of South Carolina, USA)
"Establishing the Pituitary Progenitors in Rathke's Pouch"
9:25 am - 9:40 am
Discussion
9:40 am - 9:55 am
Selected from Poster Abstracts: Laura Kerosuo (California Institute of Technology, USA)
"cMyc Regulates the Size of the Premigratory Neural Crest Stem Cell Pool"
9:55 am - 10:00 am
Discussion
10:00 am - 10:25 am
Jean-Francois Cloutier (Montreal Neurological Institute, McGill University, Canada)
"Unique Molecular Pathway Regulating both Olfactory Progenitor Cell and Neural Crest Cell Differentiation"
10:25 am - 10:40 am
Discussion
10:40 am - 11:10 am
Coffee Break
11:10 am - 11:25 am
Selected from Poster Abstracts: Annita Achilleos (Baylor College of Medicine, USA)
"Ronin (Thap11): A New Transcription Factor Implicated in Neural Crest and Craniofacial Development"
11:25 am - 11:30 am
Discussion
11:30 am - 11:45 am
Selected from Poster Abstracts: James Hackland (University of California, Riverside, USA)
"Controlling for the Unpredictable Contribution of Endogenous BMP Expression During Differentiation of Human Pluripotent Stem Cells into Neural Crest"
11:45 am - 11:50 am
Discussion
11:50 am - 12:15 pm
Carole LaBonne (Northwestern University, USA)
"Stem Cells, Gene Regulatory Networks and the Evolution
of Vertebrates"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Diseases of Neural Crest and Cranial Placodes
Discussion Leader: Martin Garcia-Castro (University of California, Riverside, USA)
7:30 pm - 7:55 pm
Constantine Stratakis (National Institute of Child Health and Human Development, NIH, USA)
"GPR101 and Pituitary Tumors"
7:55 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Selected from Poster Abstracts: Hannah Long (Stanford University, USA)
"Investigating the Long-Range Regulation of SOX9 Gene Expression During Cranial Neural Crest Development"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Selected from Poster Abstracts: Margot Bowen (Stanford University, USA)
"Defining the Spectrum of Phenotypes that Can Be Induced by Different Levels of p53 Activation in Neural Crest Cells"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
Salil Lachke (University of Delaware, USA)
"RNA Binding Proteins in Lens Development and Disease"
9:15 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure