Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Systems Biology of Sensory Organs
Discussion Leader: Sally Moody (George Washington University, United States)
7:40 pm - 8:05 pm
Clare Baker (University of Cambridge, United Kingdom)
"Insights into Electrosensory Versus Mechanosensory Organ Formation in the Sterlet Lateral Line"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
Linda Barlow (University of Colorado Anschutz Medical Campus, United States)
"Taste Bud Cell Lineage and Longevity."
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Ailín Buzzi (King's College London, United Kingdom)
"A Systems Biology and Evolutionary Approach for the Emergence of the Vertebrate Ear."
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Shannon Carroll (Children's Hospital of Philadelphia, United States)
"A Key Role for the RNA Splicing Regulators Esrp1/2 in Pituitary Morphogenesis from the Adenohypophyseal Placode"
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
EMT, Matrix Interactions and Forces
Discussion Leader: M. Angela Nieto (Instituto de Neurociencias, CSIC-UMH, Spain)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:30 am
Guojun Sheng (Kumamoto University, Japan, Japan)
"Developmental Epithelial-Mesenchymal Transition: Form, Function and Evolutionary Conservation"
9:30 am - 9:40 am
Discussion
9:40 am - 9:55 am
Sergei Sokol (Icahn School of Medicine at Mount Sinai , United States)
"Actomyosin-dependent Forces in Neural Crest Specification"
9:55 am - 10:05 am
Discussion
10:05 am - 10:20 am
Emma Moore (Stowers Institute for Medical Research, United States)
"The Cellular Dynamics of Neural Crest Cell Delamination in Mammalian Craniofacial Development"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
Marie Breau (Institut de Biologie Paris Seine, France)
"Mechanical Interactions between Tissues during Olfactory Placode Morphogenesis in Zebrafish"
11:25 am - 11:35 am
Discussion
11:35 am - 11:50 am
Karen Liu (King's College London, United Kingdom)
"GSK3 Regulation of Lpd is Required for Dynamic Cell Protrusions in Mouse Neural Crest Migration"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:15 pm
Erica Hutchins (University of California, San Francisco (UCSF), United States)
"Post-transcriptional Control Mechanisms Regulate Neural Crest Cell EMT"
12:15 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizers: Paul Trainor (Stowers Institute for Medical Research, United States) and Lisa Taneyhill (University of Maryland, United States)
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Single and Collective Cell Migration Dynamics
Discussion Leader: Roberto Mayor (University College London, United Kingdom)
6:00 pm - 6:05 pm
Introduction by Discussion Leader
6:05 pm - 6:30 pm
Julia Ganz (Michigan State University, United States)
"The Brain in the Gut: Enteric Nervous System Development and Function in Zebrafish"
6:30 pm - 6:40 pm
Discussion
6:40 pm - 6:55 pm
Rosa Uribe (RICE UNIVERSITY, United States)
"A Combinatorial Code of Hox Genes Differentially Affects Vagal Neural Crest Cell Development"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:15 pm
Dominique Alfandari (University of Massachusetts amherst, United States)
"Adam11 Regulates BMP4 and Wnt Signaling Controlling Neural Tube Closure and CNC Migration"
7:15 pm - 7:20 pm
Discussion
7:20 pm - 7:35 pm
William Martinson (University of Oxford, United Kingdom)
"Extracellular Matrix Remodelling by Lead Chick Cranial Neural Crest Cells is a Major Determinant of Robust Collective Migration"
7:35 pm - 7:40 pm
Discussion
7:40 pm - 7:55 pm
Marcela Marques Moreno (King's College London, United Kingdom)
"Kinase Codes Controlling Cranial and Trunk Neural Crest Cell Migration"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Neural Crest Cell and Cranial Placode Interactions
Discussion Leader: Andrea Streit (King's College London, United Kingdom)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:30 am
Susan Wray (NINDS, United States)
"A Tale of Two Lineages: Neural Crest vs Placodal Ectoderm GnRH Cells"
9:30 am - 9:40 am
Discussion
9:40 am - 9:55 am
Ron Yu (Stowers Institute, United States)
"Neural Crest Cells are the Precursor of the Navigator Population of Murine Olfactory Sensory Neurons"
9:55 am - 10:05 am
Discussion
10:05 am - 10:20 am
Carrie Leonard (University of Maryland, College Park, United States)
"Distinct Origins of Trk-expressing Neuronal Subpopulations in the Murine Trigeminal Ganglion"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
Tanya Whitfield (University of Sheffield, United Kingdom)
"The Adhesion GPCR Adgrg6 (Gpr126): Expression and Function in Placodal and Neural Crest Derivatives in the Zebrafish"
11:25 am - 11:35 am
Discussion
11:35 am - 11:50 am
Victoria Prince (The University of Chicago, United States)
"A Role for the Cranial Neural Crest in Zebrafish Anterior Lateral Line Development"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:15 pm
Abigail Tucker (King's College London, United Kingdom)
"Co-ordinating Development of the Middle and External Ear: Role of Neural Crest-derived Mesenchyme"
12:15 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Regulation of Neural Crest Cell and Cranial Placode Development and Differentiation
Discussion Leader: Jean-Pierre Saint-Jeannet (New York University College of Dentistry, United States)
6:00 pm - 6:05 pm
Introduction by Discussion Leader
6:05 pm - 6:30 pm
Paolo Forni (University at Albany, SUNY, United States)
"The Intertwined Development of Vomeronasal Neurons, Terminal Nerve, and Olfactory Ensheathing Cells of Rodents"
6:30 pm - 6:40 pm
Discussion
6:40 pm - 7:05 pm
Andrew Groves (Baylor College of Medicine, United States)
"The Role of Foxi3 in Neural Crest and Placode Development and Human Disease"
7:05 pm - 7:15 pm
Discussion
7:15 pm - 7:30 pm
Ana Azambuja (Boston Children's Hospital, United States)
"In Vivo STARR-seq Uncovers Functional and Spatial Heterogeneity of Neural Crest Enhancers"
7:30 pm - 7:35 pm
Discussion
7:35 pm - 7:50 pm
Anne-Hélène Monsoro-Burq (Institut Curie / Universite Paris-Saclay, France)
"From Neural Border to Migratory Stage: A Comprehensive Single Cell Roadmap of the Timing and Regulatory Logic Driving Cranial and Vagal Neural Crest Emergence"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Morphogenesis, Patterning and Evolution
Discussion Leader: Thomas Schilling (University of California, Irvine, United States)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:30 am
Kristen Kwan (University of Utah, United States)
"Your Neighborhood Shapes You: Tissue-Tissue Interactions in Vertebrate Eye Morphogenesis"
9:30 am - 9:40 am
Discussion
9:40 am - 9:55 am
Ajay Chitnis (National Institute of Child Health and Human Development, NIH, United States)
"Migration and Morphogenesis of the Zebrafish Posterior Lateral Line Primordium: Insights from High-resolution Imaging and High-throughput Morphological Segmentation"
9:55 am - 10:05 am
Discussion
10:05 am - 10:20 am
Sabrina Fox (University of Alberta, Canada)
"bmp3 is a Novel Regulator of Zebrafish Jaw Morphogenesis"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
Eric Theveneau (CNRS - Universite Paul Sabatier, France)
"Non-Canonical Roles of Matrix Metalloproteinases during Xenopus Neural Crest EMT and Migration"
11:25 am - 11:35 am
Discussion
11:35 am - 11:50 am
Lindsey Barske (Cincinnati Children's Hospital Medical Center, United States)
"Nr2f Nuclear Receptors Support the Survival and Ectomesenchyme Transition of Cranial Neural Crest"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:15 pm
Hiroki Higashiyama (The University of Tokyo, Japan)
"Morphological Evolution of the Mammalian Face through the Reorganization of the Facial Prominences"
12:15 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Neurocristopathies and Sensory System Disorders
Discussion Leader: Marianne Bronner (California Institute of Techno, United States)
6:00 pm - 6:25 pm
Frances Lefcort (Montana State University, United States)
"What Elp1 Teaches Us About PNS Development"
6:25 pm - 6:35 pm
Discussion
6:35 pm - 7:00 pm
Hideki Enomoto (Kobe University Graduate School of Medicine, Japan)
"Schwann Cell Precursor-Derived Neurogenesis in Development and Pathology of the Autonomic Nervous System"
7:00 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
Casey Griffin (New York University College of Dentistry, United States)
"The Function of SF3B4 in Neural Crest and Craniofacial Development"
7:25 pm - 7:35 pm
Discussion
7:35 pm - 7:50 pm
Duncan Sparrow (University of Oxford, United Kingdom)
"Perturbation of Neural Crest Development in Animal Models of Environmental Causes of Congenital Heart Disease"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Stem Cells and Multipotency
Discussion Leader: Mai Har Sham (The Chinese University of Hong Kong, Hong Kong SAR China)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:30 am
Robert Kelsh (University of Bath, United Kingdom)
"Cyclical Fate Restriction: a Novel View of How the Neural Crest Might Work"
9:30 am - 9:40 am
Discussion
9:40 am - 9:55 am
Filippo Rijli (Friedrich Miescher Institute for Biomedical Research, Switzerland)
"Multiple Inter-TAD Long-range Super-enhancers Control Hoxa Gene Function in Cranial Neural Crest Cells"
9:55 am - 10:05 am
Discussion
10:05 am - 10:20 am
Maria Eleni Kastriti (Center for Brain Research, Medical University of Vienna, Austria, Austria)
"Using Single Cell Transcriptomics to Redefine Schwann Cell Precursors: Functions Beyond Myelination"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
H. Joseph Yost (University of Utah, United States)
"Cardiovascular Development and Predisposition to Adult Heart Disease"
11:25 am - 11:35 am
Discussion
11:35 am - 11:50 am
Shashank Gandhi (University of California, Berkeley, United States)
"A “Cardiactomesenchymal” Neural Crest in the Hindbrain Governs Outflow Tract Septation"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:15 pm
Chantal Thibert (Institute for Advanced Biosciences - Grenoble, France)
"Metabolic Basis of Neural Crest Cell Plasticity"
12:15 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Neural Crest Cells in Cancer
Discussion Leader: Lukas Sommer (University of Zurich, Switzerland)
6:00 pm - 6:05 pm
Introduction by Discussion Leader
6:05 pm - 6:30 pm
Valerie Castellani (MELIS, Claude Bernard University Lyon 1, CNRS5284 INSERM1314, Neuromyogene institute, France)
"Studying Neuroblastoma in Light of its Embryonic Origin: Impact of Cellular and Molecular Dialogs with Healthy Developing Tissues"
6:30 pm - 6:40 pm
Discussion
6:40 pm - 7:05 pm
Ankur Saxena (University of Illinois Chicago, United States)
"Hitching a Ride with the Neural Crest: Driving Towards Differentiation"
7:05 pm - 7:15 pm
Discussion
7:15 pm - 7:30 pm
Stina Andersson (Lund University, Sweden)
"Trunk Neural Crest Enriched MOXD1 Suppresses Tumor Growth in Neuroblastoma"
7:30 pm - 7:40 pm
Discussion
7:40 pm - 7:55 pm
Ryan Samuel (University of California San Francisco, United States)
"Generation of Schwann Cell-derived Melanocytes from hPSCs Identify Pro-metastatic Factors in Melanoma"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure