SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | KEYNOTE LECTURES |
| Discussion Leader: Franck Polleux |
7:40 pm - 8:20 pm | Huda Zoghbi (Baylor Medical College, HHMI)
"What I have learned about Neurodevelopment Studying Humans and Model Organisms" |
8:20 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | David Ginty (Johns Hopkins University, HHMI)
"The development and organization of neurons that underlie the sense of touch" |
9:15 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | NEUROGENESIS AND BRAIN PATTERNING |
| Discussion Leader: Fiona Doetsch |
9:00 am - 9:20 am | Wieland Huttner (Max Planck Institute Dresden)
"Neural stem and progenitor cells and the evolution of the cerebral cortex" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Songhai Shi (Sloan Kettering Institute NY)
"Lineage-dependent functional development of the neocortex" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Group Photo / Coffee Break |
10:30 am - 10:50 am | Andrea Brand (MRC Univ. Cambridge, UK)
"Nutrient control of neural stem cells" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Kenneth Campbell (Cincinnati Children's Research Foundation)
"Spatial and temporal roles of Gsx genes in the specification of telencephalic cell fates" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:45 am | Maria Lehtinen (Children's Hospital at Harvard)
"Instructive cues for neural stem cells in the cerebrospinal fluid" |
11:45 am - 11:50 am | Discussion |
11:50 am - 12:05 pm | Santos Franco (The Scripps Research Institute)
"A Lineage of Radial Glial Cells Fated to Generate Upper Layer Neurons"
|
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | Zhen Huang (Univ. Wisconsin)
"Radial Glia regulate nascent brain vascular network stabilization via inhibition of Wnt signaling"
|
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session 1 |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | CELL TYPE SPECIFICATION |
| Discussion Leader: Andrea Brand |
7:30 pm - 7:50 pm | Marc Freeman (Univ. Mass. - HHMI)
"Neuron-glia signaling during astrocyte development" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Paola Arlotta (Harvard Med. School)
"Molecular development of projection neuron subtypes in the neocortex" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Hynek Wichterle (Columbia Univ.)
"Transcriptional logic of motor neuron programming" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Soo-Kyung Lee (Oregon Health Medical)
"Gene networks governing cholinergic neuronal identity in vertebrate CNS"
|
9:20 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | NEURAL STEM CELLS |
| Discussion Leader: Hynek Wichterle |
9:00 am - 9:20 am | Yoshiki Sasai (Riken Kobe, Japan)
"Self-organization of neural structures in 3D ES cell culture" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Stewart Anderson (Cornell Univ.)
"Studying synaptogenesis onto and by human forebrain GABAergic interneurons" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 10:50 am | Pierre Vanderhaeghen (ULB/IRIBHM)
"Mechanisms of specification of cortical neurons, from mouse to man" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Guo-li Ming (Johns Hopkins Univ.)
"Regulation of neuronal development by risk genes for mental disorders, from mice to humans" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:45 am | Yutaka Yoshida (Cincinnati Children's Research Foundation)
"Molecular mechanisms underlying circuit development in the spinal cord"
|
11:45 am - 11:50 am | Discussion |
11:50 am - 12:05 pm | Yasushi Nakagawa (Univ. Minnesota)
"Afferent control of neocortical development in mice"
|
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | Bassem Hassan (VIB Leuven)
"Stochastic mechanisms in the generation of stereotyped brain maps"
|
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session 2 |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | NEURONAL MIGRATION AND MORPHOGENESIS |
| Discussion Leader: Marc Freeman |
7:30 pm - 7:50 pm | Oscar Marin (Alicante, Spain)
"Mechanisms of neuronal migration in the cerebral cortex" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Francois Guillemot (MRC Mill Hill, UK)
"Transcriptional and post-transcriptional regulation of neurogenesis in the adult hippocampus" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Kang Shen (Stanford Univ. HHMI)
"Cellular and molecular mechanisms for synaptic partner selection in vivo" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:15 pm | Goichi Miyoshi (NYU)
"Prox1 regulates the migration and maturation of caudal ganglionic eminence-derived cortical interneurons"
|
9:15 pm - 9:20 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | WIRING THE NERVOUS SYSTEM I |
| Discussion Leader: Guo-li Ming |
9:00 am - 9:20 am | Maya Shelly (Stony Brook NY)
"Molecular mechanisms underlying neuronal polarization" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | William Harris (Cambridge Univ. UK)
"The polarization of neurons in the zebrafish retina" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 10:50 am | Dietmar Schmucker (VIB Leuven)
"Novel molecular pathways underlying specificity of axon branching and connectivity in CNS development" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Christine Holt (Cambridge UK)
"Role of axonal translation in patterning visual connections" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Artur Kania (McGill University)
"Netrin-ephrin synergy in motor axon guidance" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Wes Grueber (Columbia Univ.)
"Dendritic morphogenesis in Drosophila"
|
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session 3 |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
7:30 pm - 9:30 pm | WIRING THE NERVOUS SYSTEM II |
| Chair: Cagla Eroglu |
7:30 pm - 7:50 pm | Josh Sanes (Harvard Univ.)
"Laminar and lateral specificity in the retina" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Linda Van Aelst (CSHL)
"Rho regulators in neuronal development and disease" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Andrew Huberman (UCSD)
"Wiring visual circuits to perform specific functions" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Alex Kolodkin (Johns Hopkins Univ., HHMI)
"Molecular mechanisms underlying the establishment of neural connectivity"
|
9:20 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | SYNAPTOGENESIS AND CIRCUIT FORMATION |
| Discussion Leader: Kang Shen |
9:00 am - 9:20 am | Silvia Arber (FMI Basel)
"Organizational principles of antagonistic motor circuits" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Kim McAllister (UC Davis)
"Novel roles for immune molecules in cortical development" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 10:50 am | Cagla Eroglu (Duke University)
"How do astrocytes control synaptic development?" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Joshua Corbin (Children's National Med. Center, Washington DC)
"Embryonic patterning mechanisms for the establishment of limbic system circuitry and innate behaviors"
|
11:20 am - 11:30 am | Discussion |
11:30 am - 11:45 am | Julien Spatazza (College de France, Paris- France)
"Otx2 homeoprotein transcrition factor regulates plasticity in the adult mouse visual cortex"
|
11:45 am - 11:50 am | Discussion |
11:50 am - 12:05 pm | Dorothy Schafer (Harvard Medical School)
"Microglia and the complement cascade: Shaping neural circuits in the developing brain"
|
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | Tudor Badea (NIH)
"Molecular Genetics of Retinal Ganglion Cell Type Differentiation"
|
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session 4 |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | HUMAN BRAIN EVOLUTION |
| Discussion Leader: Pierre Vanderhaeghen |
7:30 pm - 7:50 pm | Evan Eichler (Univ. Washington, HHMI)
"Genome structural variation, neurocognitive disease and evolution" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:15 pm | Kaumudi Joshi (The Scripps Research Institute)
"Role of human-specific gene duplications during brain development" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:35 pm | Kenneth Kwan (Yale University)
"Species-Dependent Post-transcriptional Regulation in the Developing Neocortex"
|
8:35 pm - 8:40 pm | Discussion |
8:40 pm - 9:00 pm | Arnold Kriegstein (UCSF)
"New insights into neural stem and progenitor cells in human cortical development and evolution" |
9:00 pm - 9:10 pm | Discussion |
9:10 pm - 9:20 pm | Concluding Remarks |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |