Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: From Stem Cells to Networks
Discussion Leader: Rosalind Segal (Harvard Medical School / Dana-Farber Cancer Institute, USA)
7:40 pm - 8:25 pm
Andrea Brand (The Gurdon Institute, University of Cambridge, United Kingdom)
"Time to Wake Up: Regulation of Neural Stem Cell Quiescence and Reactivation"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 9:20 pm
Christopher Walsh (Division of Genetics and Genomics, Boston Children's Hospital / Howard Hughes Medical Institute, USA)
"Mechanisms of Development and Evolution of Human Cerebral Cortex"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Epigenetic Regulation of Neural Development
Discussion Leader: Claude Desplan (New York University, USA)
9:00 am - 9:30 am
Azad Bonni (Washington University School of Medicine, USA)
"Regulation of Neuronal Connectivity and Plasticity in the Brain by Chromatin Remodeling"
9:30 am - 9:35 am
Discussion
9:35 am - 10:05 am
Kristen Kroll (Washington University School of Medicine, USA)
"Regulatory Networks that Specify Human Cortical Interneurons and Their Dysregulation in Neurodevelopmental Disorders"
10:05 am - 10:10 am
Discussion
10:10 am - 10:40 am
Coffee Break
10:40 am - 11:10 am
Michael Dyer (St. Jude Children's Research Hospital, USA)
"Cellular Pliancy in Retinal Development and Disease"
11:10 am - 11:15 am
Discussion
11:15 am - 11:45 am
Jessica Tollkuhn (Cold Spring Harbor Laboratory, USA)
"Estrogen Regulation of Sex Differences in the Brain"
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
Rachel Bandler (New York University School of Medicine, USA)
"Mapping the Developmental Trajectories of Forebrain Inhibitory Neurons"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
Caitlin Taylor (Stanford University, USA)
"Chromatin Remodeling Modulates Membrane Trafficking Programs During the Establishment of Complex Dendritic Morphology"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
Organizer: Lisa Goodrich (Harvard Medical School, USA)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Glial Cell Differentiation and Biology
Session in memory of Ben Barres.
Discussion Leader: Andrew Huberman (Stanford University, USA)
7:30 pm - 7:55 pm
Marc Freeman (Vollum Institute, Oregon Health & Science University, USA)
"Neuron-Glia Signaling During Neural Circuit Remodeling"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:25 pm
Christian Klambt (Universität Münster, Germany)
"The Impact of Glial Barriers on the Behavior of Drosophila Larvae"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:55 pm
Benjamin Deneen (Baylor College of Medicine, USA)
"Transcriptional Control of Astrocyte Form and Function in the Brain"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:25 pm
Maria Lehtinen (Boston Children's Hospital, USA)
"Cerebrospinal Fluid-Based Signaling in the Developing Brain"
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Formation of Synapses and Circuits
Discussion Leader: Roy Sillitoe (Baylor College of Medicine, USA)
9:00 am - 9:30 am
Carina Hanashima (Waseda University, Japan)
"Neuronal Subtype Transitions and Integration in the Cerebral Cortex"
9:30 am - 9:40 am
Discussion
9:40 am - 10:10 am
Kang Shen (Stanford University, USA)
"Concerted Regulation of Synaptic Genes by a Nuclear Export Complex"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:20 am
Irene Miguel-Aliaga (MRC London Institute of Medical Sciences, Imperial College London, United Kingdom)
"Clever Guts in Hungry Flies: Enteric Neurons and the Control of Nutritional Decisions in Drosophila "
11:20 am - 11:30 am
Discussion
11:30 am - 12:00 pm
Matthew Pecot (Harvard Medical School, USA)
"Molecular Mechanisms Underlying the Precision of Synaptic Connectivity"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
Orly Reiner (Weizmann Institute of Science, Israel)
"Brain Organoid on a Chip to Model Lissencephaly"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Regulating Translation in Neural Development: Spatial Challenges of Axons and Dendrites
Discussion Leader: Azad Bonni (Washington University School of Medicine, USA)
7:30 pm - 7:40 pm
Lucas Cheadle (Harvard Medical School, USA)
"Visual Experience-Dependent Expression of Fn14 Is Required for Retinogeniculate Refinement"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Beverly Piggott (University of California, San Francisco, USA)
"Sodium Channel Disruption Affects Drosophila Stem Cell and Brain Tumor Development"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:25 pm
Yan Song (Peking University, China)
"Transcriptional and Epigenetic Control of Timely Neural Stem Cell Fate Commitment"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:55 pm
Avraham Yaron (Weizmann Institute of Science, Israel)
"Intrinsic and Extrinsic Control of Axonal Pruning"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:25 pm
Florence Besse (iBV - Institute of Biology Valrose, Université Nice Sophia Antipolis, France)
"Transport of RNP Granules in Neuronal Remodeling"
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Stem Cells and Neural Precursors that Form Neurons and Glia
Discussion Leader: Corinne Houart (King's College London, United Kingdom)
9:00 am - 9:30 am
Paola Arlotta (Harvard University, USA)
"Understanding Human Brain Development and Disease: From the Embryo to Organoids"
9:30 am - 9:40 am
Discussion
9:40 am - 10:10 am
Ron Parchem (Baylor College of Medicine, USA)
"MicroRNA Regulation of Neural Fate Specification"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:20 am
Debby Silver (Duke University Medical Center, USA)
"Intersecting RNA Fate and Cell Fate in the Developing Neocortex"
11:20 am - 11:30 am
Discussion
11:30 am - 12:00 pm
Andrew Huberman (Stanford University, USA)
"Brain Circuits that Merge What We See with How We Feel to Determine What We Do"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
Filipe Pinto Teixeira (New York University, USA)
"Emergence of Retinotopy in the Developing Drosophila Motion Vision System"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Cell Fate and Differentiation
Discussion Leader: Corey Harwell (Harvard Medical School, USA)
7:30 pm - 8:00 pm
Chenghua Gu (Harvard Medical School, USA)
"Interactions Between Nervous and Vascular Systems in the CNS"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
Corey Harwell (Harvard Medical School, USA)
"Mechanisms for Generating Diversity in the Mammalian Forebrain"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
Roy Sillitoe (Baylor College of Medicine, USA)
"Pattern Formation and Connectivity in the Mouse Cerebellum"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Axons and Dendrites: Pathfinding and Establishing Connections
Discussion Leader: Matthew Pecot (Harvard Medical School, USA)
9:00 am - 9:30 am
Lisa Goodrich (Harvard Medical School, USA)
"Eyes on the Ear: Glial-Guided Neurite Outgrowth Creates a Wiring Scaffold in the Cochlea"
9:30 am - 9:35 am
Discussion
9:35 am - 10:05 am
Yimin Zou (University of California, San Diego, USA)
"Signaling Mechanisms for Axon Guidance and Synapse Formation"
10:05 am - 10:10 am
Discussion
10:10 am - 10:40 am
Coffee Break
10:40 am - 11:10 am
Thomas Schwarz (Boston Children's Hospital, USA)
"Kinetochore Proteins Function in Post-Mitotic Neural Development"
11:10 am - 11:15 am
Discussion
11:15 am - 11:45 am
Corinne Houart (King's College London, United Kingdom)
"The Non-Nuclear Pool of Splicing Factors Modifies the Axonal Transcriptome During Motor Development"
11:45 am - 11:50 am
Discussion
11:50 am - 12:20 pm
John Huguenard (Stanford University, USA)
"Enduring Cortical Axonal Hypoexcitability in a Model of Maternal Immune Activation"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Computing Development
Discussion Leader: Marc Freeman (Vollum Institute, Oregon Health & Science University, USA)
7:30 pm - 8:00 pm
Thomas Clandinin (Stanford University, USA)
"Dissecting the Circuit and Molecular Mechanisms Underpinning Visual Computation"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
Esteban Mazzoni (New York University, USA)
"Divergent Ascl1 and Neurog2 Neuronal Programming"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Laura Pereira (Columbia University, USA)
"Timing Mechanisms of Sexually Dimorphic Nervous System Differentiation"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Jan Lui (Stanford University, USA)
"Molecular, Anatomical and Behavioral Dissection of mPFC Projection Neuron Heterogeneity"
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure