Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Principles of Neurogenesis
Discussion Leader: Rosalind Segal (Harvard Medical School and Dana-Farber Cancer Institute, United States)
7:40 pm - 8:00 pm
Chris Doe (HHMI/ Univ Oregon, United States)
"The Role of Temporal Identity in Establishing Neural Circuits"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
Yukiko Gotoh (University of Tokyo, Japan)
"Chromatin Regulation of Neuronal Differentiation"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:20 pm
Magdalena Goetz (Ludwig Maximilians University of Munich, Germany)
"New Mechanisms in Neurogenesis – From Centrosome to Liquid Phase Transition"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Neural Cell Fate Specification
Discussion Leaders: Hernan Lopez-Schier (Helmholtz Zentrum München, Germany)
9:00 am - 9:20 am
Shubha Tole (Tata Institute of Fundamental Research, India)
"Wnts up at the Telencephalic Midline"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
Brooke D'Arcy (Duke University, United States)
"Sub-cellular Transcriptome and Proteome of Radial Glia Reveal New Regulatory Mechanisms of Cortical Development"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Karthik Shekhar (University of California, Berkeley, United States)
"Vision-Dependent and -Independent Molecular Specification of Neurons in the Visual System"
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
Laure Bally-Cuif (Institut Pasteur and CNRS UMR3538, France)
"Mechanisms Driving the Construction and Maintenance of Adult Neural Stem Cell Ensembles"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Jessica Treisman (NYU Langone Health, United States)
"Patterning the Visual System with a Sidekick"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
Alessandra Pierani (INSERM, France)
"Transient Moving Organizers: Life and Death in Cortical Development and Evolution"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
Bassem Hassan (Paris Brain Institute, France)
"Temporal Control of Neurogenesis"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizers: Shubha Tole (Tata Institute of Fundamental Research, India) and Jessica Tollkuhn (Cold Spring Harbor Laboratory, United States)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
The Generation of Neural Diversity
Discussion Leader: Yukiko Gotoh (University of Tokyo, Japan)
7:30 pm - 7:50 pm
Maria Antonietta Tosches (Columbia University, United States)
"The Evolutionary Origins of Cortical Cell Types"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Orkun Akin (David Geffen School of Medicine at UCLA, United States)
"A Discrete Neuronal Population Coordinates Brain-Wide Developmental Activity"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Mehmet Neset Ozel (New York University, United States)
"Coordinated Control of Neuronal Differentiation and Wiring by a Sustained Code of Transcription Factors"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Joshua Corbin (Children's National Research Institute, United States)
"Developmental and Postnatal Trajectories of Amygdala Lineage Divergence"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Stavros Lomvardas (Columbia University, United States)
"Determining Stochasticity: Homeotic Regulation of Zonal Olfactory Receptor Gene Expression"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Neural Lineages: From Genomics to Imaging
Discussion Leader: Laure Bally-Cuif (Institut Pasteur and CNRS UMR3538, France)
9:00 am - 9:20 am
Zhirong Bao (Memorial Sloan Kettering Cancer Center, United States)
"Collective Cell Behaviors in Shaping the Worm’s Nervous System"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
Allison Bond (University of Pennsylvania, United States)
"Developmental Emergence of Adult Neural Stem Cells in the Hippocampus"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Edmund Au (Columbia University Irving Medical Center, United States)
"St18 Specifies Globus Pallidus Projection Neuron Identity in the MGE Lineage"
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
Catarina Homem (NOVA Medical School, Universidade NOVA de Lisboa, Portugal)
"Temporal Regulation of Drosophila Neural Stem Cells During Development"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Simon Hippenmeyer (Institute of Science and Technology Austria, Austria)
"Principles of Neural Stem Cell Lineage Progression"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Meike Lobb-Rabe (University of Chicago, United States)
"Dpr10 and Nocte are Required for Drosophila Motor Axon Pathfinding"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Dhananjay Huilgol (Duke University, United States)
"Direct and Indirect Neurogenesis Generate a Mosaic of Distinct Glutamatergic Projection Neuron Types and Cortical Subnetworks"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
Christian Mayer (Max Planck Institute for Biological Intelligence, Germany)
"Single-Cell Delineation of Lineage and Genetic Identity in the Mouse Forebrain"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Evolution of Brain Development
Discussion Leader: Zhirong Bao (Memorial Sloan Kettering Cancer Center, United States)
7:30 pm - 7:50 pm
Alejandro Sanchez Alvarado (HHMI/Stowers Institute for Medical Research, United States)
"Wnt and TGF-ß Coordinate Growth and Patterning to Regulate Size-Dependent Behavior"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Naomi Shvedov (Boston University, United States)
"In vivo Imaging in Transgenic Songbirds Reveals Superdiffusive Neuron Migration in the Adult Brain"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Nagham Khouri Farah (UConn Health, United States)
"Foxp1 and Foxp2 Regulate Cerebellar Hemisphere Formation by Controlling the Diversification of Purkinje Cells"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Victor Borrell (CSIC, Spain)
"Evolution of Cortical Progenitor Cell Diversity"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Detlev Arendt (EMBL, Germany)
"The Conserved Developmental Core of the Bilateral Brain"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Axon Generation and Degeneration
Discussion Leader: Maria Antonietta Tosches (Columbia University, United States)
9:00 am - 9:20 am
Dong Yan (Duke University, United States)
"Against the Force of Aging: the Neuroprotective Function of TMC Proteins in C. elegans"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Samantha Butler (University of California, Los Angeles, United States)
"The Role of the BMPs Specifying Dorsal Spinal Neural Cell Fate"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Dietmar Schmucker (LIMES Institute University Bonn, Germany)
"Contingency Signaling in Axonal Wiring, Maintenance, and Synapse Formation"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Rosalind Segal (Harvard Medical School and Dana-Farber Cancer Institute, United States)
"Transporting RNAs to Promote Axon Survival"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Ev Nichols (Stanford University, United States)
"A Conserved E3 Ubiquitin Ligase Amplifies UNC-6/Netrin Signaling During Axon Formation"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Adam Isabella (Fred Hutchinson Cancer Center, United States)
"What Happens in Vagus: Divergent Modes of Nerve Patterning in Development and Regeneration"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
Stephanie Gupton (University of North Carolina at Chapel Hill, United States)
"Regulating Growth Cone Filopodia and Dendritic Spines via Non-Degradative Ubiquitination"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
7:30 pm - 9:30 pm
Function of Glia in Development
Discussion Leader: Samantha Butler (University of California, Los Angeles, United States)
7:30 pm - 7:50 pm
Vilaiwan Fernandes (University College London, United Kingdom)
"Glia Relay Signals to Promote Neuronal Development in the Visual System of Flies"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Jiami Guo (University of Calgary, Canada)
"Dissecting the Role of Primary Cilia in Astrocytes"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Santos Franco (University of Colorado - Anschutz Medical Campus, United States)
"Molecular Mechanisms of Oligodendrocyte Fate Specification"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Maxwell Heiman (Harvard Medical School and Boston Children's Hospital, United States)
"Development and Specificity of Neuron-Glia Attachments"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Cody Smith (University of Notre Dame, United States)
"Glial and Neuronal Interactions that Build the Nervous System"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Development of Neural Circuitry
Discussion Leader: Cody Smith (University of Notre Dame, United States)
9:00 am - 9:20 am
Richard Mann (Columbia University Irving Medical Center, United States)
"The Development of the Adult Neuromuscular System of Drosophila"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
Kristen D'Elia (NYU School of Medicine, United States)
"Identifying Molecular Determinants of Spinal Neurons Important for Fast Locomotion"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Maria Ahmed (University of Michigan, Ann Arbor, United States)
"Hacking Development to Test Models of Sensory Coding"
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
Yishi Jin (University of California San Diego, United States)
"Molecular Genetic Mechanisms of Axon and Synapse Maintenance"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Niels Ringstad (NYU School of Medicine, United States)
"Developmental Mechanisms that Endow Specialized Neurons with Unique Physiology"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
Genevieve Konopka (University of Texas Southwestern Medical Center, United States)
"Cell-Type Specific Transcriptional Networks Related to Autism"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
Hernan Lopez-Schier (Helmholtz Zentrum München, Germany)
"Development and Homeostasis of a Mechanosensory Circuit"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Keynote Session: Human Development and Disease
Discussion Leader: Genevieve Konopka (University of Texas Southwestern Medical Center, United States)
7:30 pm - 7:50 pm
Giorgia Quadrato (Keck School of Medicine, United States)
"Upgrading the Physiological Relevance of Human Brain Organoids"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Emelie Braun (Karolinska Institutet, Sweden)
"Early Human Brain Development at Single-Cell Resolution"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
Rick Livesey (University College London, United Kingdom)
"Human Cerebral Cortex Development in Health and Disease"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 9:20 pm
Arturo Alvarez-Buylla (University of California, San Francisco, United States)
"Neural Stem Cells and Adult Neurogenesis: From Birds and Mice to Humans"
9:20 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
Closing Remarks
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure