Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Cell Fate In the Nervous System
7:40 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:20 pm
"Microglia in The Choreography of Cerebral Development"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Multiple Regulators of Genome Organization Coordinate Developmentally-Timed Changes in Neural Progenitor Competence"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Evolution of Neuronal Cell Types: Paraneurons"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:20 am
"Regulation and Diversity of Adult Neural Stem Cells"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Leveraging CRISPR Technology to Interrogate Cortical Development Mechanisms"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"All in This Together? Non-Autonomous Mechanisms of Neural Stem Cell Reactivation"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Elucidating the Role of Neural Progenitor Cells in the Etiology of GLUT1 Deficiency Syndrome"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Identifying Cues Driving Cortical Cell Fate Specification"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Cortical Interneuron Migration in The Forebrain - An Evo-Devo Perspective"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Transport of Cyclin D2 mRNA and Protein Regulates Cell Cycle Progression in Radial Glial Cells of Placental Mammals"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Sexually Dimorphic Regulation of Quiescent Neural Progenitors in C. Elegans"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Cell Lineages and Identity
6:00 pm - 6:20 pm
"Global Views of Embryogenesis"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Self-Organizing Properties of Cortical Neurons"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:10 pm
"Directing the Timing of Neuronal Maturation in Human Pluripotent Stem Cell-Based Models"
7:10 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
"Multidimensional Investigation of Lineage Relationships and Cellular Dynamics in the Vertebrate Neural Tube"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
"Ciliary Sequestration of Smoothened Facilitates Actin Remodeling to Drive Axon Extension during Vertebrate CNS Development"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"mTORC1 Dependent Upregulation of Atf4 in Radial Glia Spares Neocortical Growth during Maternal Malnutrition"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Neural Niches and Environment
9:00 am - 9:20 am
"Glial-Vascular Interactions Shape Developing Neurons in The Mouse Cortex"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Home Sweet Home: Formation and Roles of The Neurogenic Niche"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Instinctive Behavior Circuit Development is Shaped by Sensory Input, Sex, and Function"
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"Cellular Crosstalk in Brain Development and Neurodevelopmental Disorders"
11:05 am - 11:15 am
Discussion
11:15 am - 11:35 am
"'Stuck on You’: Meninges-Brain Crosstalk during Neocortical Development"
11:35 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Sensory Integration at The Interface with The Cerebrospinal Fluid during Axial Morphogenesis"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"MicroRNA Mechanisms of Neuronal Development"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Human Disease and Variation
6:00 pm - 6:20 pm
"Brain Mosaicism in Cortical Malformations"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Cell-Type Specific Alterations Underpinning PACS Syndromes: Implications for Neural Development"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Assembly and Operation of The Neocortex under Normal and Disease Conditions"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
"Multidonor Human Cortical Chimeroids Reveal Individual Susceptibility to Neurotoxic Triggers"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Genetic and Epigenetic Features of the X Chromosome Underlie Sex-Biased Autism Prevalence"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:20 am
"How Do Astrocytes Sculpt Synaptic Circuits?"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Glial Progenitor Cells in The Drosophila CNS Redefined by Evolutionarily Conserved Mechanisms"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Towards The Molecular Signature of Human Astrocyte Evolution"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Developmental Origin and Local Signals Cooperate to Determine Septal Astrocyte Identity"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Comparative Approaches Reveal Regenerative Mechanisms in The Spinal Cord"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Unlocking the Glial Code: Mammalian-Specific Mechanisms in Blood-Brain Barrier Regulation"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Silencing of Retinal Input during Gliogenesis and Myelination Compromises Ferret Visual Cortex Gyrification"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
6:00 pm - 6:20 pm
"Nuclear Factor One Gene Function in Cortical Development"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"The Retinal Pigment Epithelium, Melanin, and Neurogenesis: Lessons from the Albino on Projection Fate"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Deterministic and Stochastic Specification of 100 Types of Visual System Neurons"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
"Biased Cell Adhesion Organizes the Drosophila Visual Motion Integration Circuit"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Probabilistic Axon Targeting Dynamics Lead to Individualized Brain Wiring"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
9:00 am - 9:20 am
"Mapping Cis - and Trans -Regulatory Consequences of Human-Specific Deletions"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Timing Mechanisms Linking Development and Evolution of The Human Brain"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"An Expanded Subventricular Zone Provides Region- And Subtype-Specific Expansion of Inhibitory Neurons in The Neonatal Brain"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Investigation of The Mechanisms Underlying the Development and Evolution of The Brain using Gyrencephalic Ferrets"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Human-Specific Genetic Modifiers of Brain Development and Their Impact on Phenotypic Expression of Neurodevelopmental Diseases"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Role of the Enhancer HAR1984 in Human Cortical Development and Evolution"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Evo-Devo Diversification of Cortical Output Channels"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Keynote Session: Foundations Of Neural Circuitry
6:00 pm - 6:20 pm
"Development of Columnar Units in The Drosophila Visual System"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Maintaining Synaptic Positions during Growth: Principles of Allometry in The C. Elegans Brain"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:10 pm
"Synapse-Specific Molecular Rules Control the Development of Excitatory Synapse Diversity"
7:10 pm - 7:15 pm
Discussion
7:15 pm - 7:50 pm
"Genomic Information, Self-Organization and the Brain - A Look Through the Fly's Eye"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure