| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | AXONAL CONTROL |
| Discussion Leader: Nancy Ip, Ph.D. (Hong Kong University of Science and Technology) |
| 7:30 pm | Introduction |
| 7:35 pm | Stephen Strittmatter, M.D., Ph.D. (Yale University)
"NogoReceptor-Mediated Control of Axonal Plasticity" |
| 8:15 pm | Frank Gertler, Ph.D. (MIT)
"Regulation of actin dynamics during neurite initiation and axon guidance" |
| 9:00 pm | Paul Letourneau, Ph.D. (University of Minnesota)
"Regulation of growth cone motility by neurotrophins" |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | NEUTROPHIC FACTOR SIGNALING I |
| Discussion Leader: Mark Bothwell, Ph.D. (University of Washington) |
| 9:00 am | Introduction |
| 9:05 am | Chris Garcia, Ph.D. (Stanford University)
"Structural and Mechanistic Explorations of p75 and Trk Receptors" |
| 9:40 am | Phil Barker, Ph.D. (Montreal Neurological Institute)
"Regulation of p75NTR Signaling Events" |
| 10:15 am | Photo Session / Coffee Break |
| 11:15 am | Sung Ok Yoon, Ph.D. (Ohio State University)
"Apoptotic action of p75" |
| 11:50 am | Carlos Ibáñez, Ph.D. (Karolinska Institute)
"Structure-function studies of p75NTR signaling" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | ACTIONS IN ADULTHOOD I |
| Discussion Leader: Louis Reichardt, Ph.D. (HHMI, University of California, San Francisco) |
| 7:30 pm | Yves-Alain Barde, Ph.D. (University of Basel)
"Modes of action of neurotrophins studied using a novel cellular assay system" |
| 8:00 pm | Perry Bartlett, Ph.D. (Queensland Brain Institute)
"P75 NTR-expressing Precursors in the Adult Brain Regulated by Neurotrophins" |
| 8:30 pm | Armin Blesch, Ph.D. (University of California, San Diego)
"Neurotrophin gene therapy for Alzheimer's disease" |
| 9:00 pm | Jeff Milbrandt, M.D., Ph.D. (Washington University School of Medicine)
"Axonal Protection via Activation of the SIRT1/NAD Pathway" |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | NEUROTROPHIC FACTOR SIGNALING II |
| Discussion Leader: Bill Mobley, M.D., Ph.D. (Stanford University) |
| 9:00 am | Introduction |
| 9:10 am | Marino Zerial, Ph.D. (Max Planck Institute of Molecular Cell biology and Genetics)
"Principles of membrane compartmentalization in endosome biogenesis, trafficking and signaling" |
| 10:00 am | Simon Halegoua, Ph.D. (SUNY at Stony Brook)
"Pincher-mediated macroendocytosis and retrograde signaling" |
| 10:45 am | Coffee Break |
| 11:05 am | Elizabeth Fisher, Ph.D. (National Hospital for Neurology & Neurosurgery, London)
"The Loa mouse which has defects in the cytoplasmic dynein heavy chain" |
| 11:45 am | Bill Snider, M.D. (University of North Carolina, Chapel Hill)
"Essential roles for Raf kinases and GSK-3b in neurotrophin-induced axon growth" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | KEYNOTE SPEAKER |
| Discussion Leader: Eric Shooter (Stanford University) |
| Michael E Greenberg, Ph.D. (Children's Hospital)
"Neuronal Activity-Dependent Regulation of Synapse Formation and Cognitive Function" |
| 9:30 pm | Business Meeting - Elections |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | SYNAPTIC ACTIONS |
| Discussion Leader: Susan Birren, Ph.D. (Brandeis University) |
| 9:00 am | Introduction |
| 9:05 am | Pietro De Camilli, Ph.D. (HHMI - Yale University)
"Signaling pathways and membrane traffic at the synapse" |
| 9:50 am | Bai Lu, Ph.D. (Section on Neural Development and Plasticity NIH)
"Yin and Yang of BDNF actions on hippocampal synaptic plasticity" |
| 10:35 am | Coffee Break |
| 11:00 am | Lino Tessarollo, Ph.D. (NCI-Frederick Neural Development Group)
"Truncated Trk Receptors: modulators of nervous system development" |
| 11:40 am | Susan Patterson Ph.D. (University of Colorado)
"BDNF Contributes to Synaptic Tagging/Capture" |
| 12:05 pm | Francis Lee, M.D., Ph.D. (Weill Cornell Medical College)
"Functional Analysis of Variant BDNF (Val66Met)" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | ACTIONS IN ADULTHOOD & DISEASE II |
| Discussion Leader: Moses Chao, Ph.D. (NYU Medical Center-Skirball Institute) |
| 7:30 pm | Luis F. Parada, Ph.D. (University of Texas Southwestern Medical Center)
"Neural Development and Regeneration" |
| 8:00 pm | Freda Miller, Ph.D. (Hospital for Sick Children - Toronto)
"Skin-derived Precursors (SKPs): From basic biology to therapeutic utility" |
| 8:30 pm | Anthony Rossomando, Ph.D. (Biogen Idec)
"Therapeutic effects of Artemin in animal models of neuropathic pain" |
| 9:00 pm | Lieve Moons, Ph.D. (Center for Transgene Technology and Gene Therapy, VIB -Belgium)
"Therapeutic advances with VEGF, an unsuspected player in neurodegeneration" |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | ACTIONS IN DEVELOPMENT I |
| Discussion Leader: Carol Mason, Ph.D. (Columbia University College) |
| 9:00 am | Introduction |
| 9:05 am | Susan McConnell, Ph.D. (Stanford University)
"On the move: mechanisms of neuronal migration" |
| 9:45 am | Rosalind Segal, M.D., Ph.D. (Dana Farber Cancer Institute)
"TrkB provides direction for migrating precursor cells" |
| 10:25 am | Coffee Break |
| 10:45 am | Kuo-Fen Lee, Ph.D. (Salk Institute)
"P45 in neural development and regeneration" |
| 11:25 am | Anders Nykjaer, M.D., Ph.D. (Aaarhus University)
"Genetic evidence for multiple roles of Sortilin in neurotrophin acton" |
| 12:05 pm | Jonah Chan, Ph.D. (Stanford University)
"The polarity protein Par-3 directly interacts with p75 to control myelination" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | ACTIONS IN ADULTHOOD & DISEASE III |
| Discussion Leader: Wilma Friedman, Ph.D. (Rutgers University) |
| 7:30 pm | Introduction |
| 7:35 pm | Shahin Rafii, M.D. (Weill Cornell Medical College)
"The role of neurotrophins in the regulation of neo-angiogenesis" |
| 8:10 pm | Valina Dawson, Ph.D. (Johns Hopkins University School of Medicine)
"Inspiration to Innovation: Lessons from Preconditioning for Neuronal Survival" |
| 8:45 pm | Holly Ingraham, Ph.D. (University of California, San Francisco)
"Selective Regulation of BDNF transcripts in the hypothalamus and Social Obesity" |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
