Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Nitric Oxide in Lung Physiology and Pathophysiology
This session features a keynote lecture from Professor Serpil Erzurum, an international expert in nitric oxide in lung physiology and pathophysiology.
Discussion Leader: Carl Koch (University of Pittsburgh, USA)
3:45 pm - 4:15 pm
Serpil Erzurum (The Cleveland Clinic Foundation , USA)
"Nitric Oxide in Lung Physiology and Pathophysiology"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Nitric Oxide Biosynthesis, Transformation, and Function
This session will focus on NO biosynthesis, transformation, and function in humans and animal models of human disease.
Discussion Leaders: Matthew Amdahl (University of Pittsburgh, USA) and Kenneth Childers (University of Maryland, Baltimore County, USA)
7:30 pm - 7:45 pm
Haitham Amal (Massachusetts Institute of Technology, USA)
"Reprogramming the SNO-Proteome in the Brain of the Shank3-KO Model of Autism Spectrum Disorder"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Vanessa Kress (University of Cologne, Germany)
"Regulation of GABAA Receptor Clustering by Gephyrin S-Nitrosylation and Dynein Light Chain"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Zixue Jin (Baylor College of Medicine, USA)
"Argininosuccinate Lyase Deficiency as a Model to Study Nitric Oxide Function in Bone"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Pallavi Bhargava (University of Arizona, USA)
"Characterization of Soluble Guanylyl Cyclase Induced Mitochondrial Biogenesis in Ischemia/Reperfusion Induced Acute Kidney Injury"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Prattusha Sengupta (AU-KBC Research Centre, Anna University, India)
"Enhancing Shelf Life of Stored Red Blood Cells with Nitric Oxide"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Shuai Yuan (LSU Health Sciences Center Shreveport, USA)
"Cystathionine Gamma-Lyase Modulates Flow-Dependent Vascular Remodeling"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Biochemical Mechanisms and Methods
This session will focus the molecular mechanisms of nitric oxide formation and signaling, as well as NO detection methodology.
Discussion Leaders: Mauro Tiso (American University, USA) and Haitham Amal (Massachusetts Institute of Technology, USA)
9:00 am - 9:15 am
Luisa Maia (Research Unit on Applied Molecular Biosciences (UCIBIO), REQUIMTE / Universidade Nova de Lisboa, Portugal)
"Nitrite Reduction by Molybdoenzymes: A Ubiquitous Pathway to Generate Nitric Oxide"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Danielle Guimaraes (University of Pittsburgh, USA)
"Nitrite Inhibits Mitochondrial Phosphodiesterase and Activates cAMP-PKA-AKAP1 Signaling to Modulate Mitochondrial Function and Cytoprotection in Normoxia"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Dominique Williams (Stony Brook University, USA)
"Nitric Oxide Regulation of Cyclic di-GMP Signaling and Biofilm Formation in Agrobacterium vitis "
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Mauro Siragusa (Goethe University Frankfurt, Germany)
"Phosphorylation of eNOS on Tyrosine 656 Contributes to Endothelial Dysfunction In Vivo "
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Alexandria Nichols (University of Alabama at Birmingham, USA)
"Improved Method of Oral Microbe Nitrate Reductase Activity Measurement "
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Loruhama Delgado Rivera (University of Illinois at Chicago, USA)
"Discovery and Design of Inhibitors of H2 S Synthesizing Enzymes"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: How to Complete an Effective and Efficient Research Fellowship
This session features a panel of established academic mentors (Drs. Erzurum, Patel, Cortese-Krott and Darley-Usmar) who will answer questions from the graduate student and post-doctoral GRS attendees. We will cover topics such as leadership, interviewing, and industry vs academia.
Discussion Leaders: Shathiyah Kulandavelu (Interdisciplinary Stem Cell Institute, University of Miami, USA) and Taiming Liu (Loma Linda University, USA)
1:30 pm - 2:30 pm
Panel Discussion
How to Complete an Effective and Efficient Research Fellowship
Victor Darley-Usmar (University of Alabama at Birmingham, USA)
Serpil Erzurum (The Cleveland Clinic Foundation , USA)
Rakesh Patel (University of Alabama at Birmingham, USA)
Miriam Cortese-Krott (Heinrich Heine University Dusseldorf, Germany)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes