| Sunday, June 21 (Evening) |
Session 1 - Protein Evolution and Genomics |
Chair: Russell Doolittle (U. C. San Diego)
- 7:30 PM - A. Kerlavage (TIGR) - "What Can We Learn from Completely Sequenced Genomes?"
- 8:00 PM - Peer Bork (Heidelberg) - "Comparing Genes and Genomes"
- 8:30 PM - Doug Brutlag (Stanford) - "Highly Specific Sequence Motifs for Genome Analysis"
- 9:00 PM - COFFEE BREAK
- 9:30 PM - Cyrus Chothia (Cambridge) - "Assignment of protein structures to genome sequences"
- 10:00 PM - Russell Doolittle (San Diego) - "URFs and ORFs Revisited"
|
| Monday, June 22 (Morning) |
Session 2 - Chromosome Structure and Chromatin |
Chair: Steven Henikoff (Fred Hutchinson Cancer Research Center)
- 9:00 AM - Steven Henikoff (Fred Hutchinson Cancer Research Center) - "Heterochromatin during the cell cycle in Drosophila"
- 9:30 AM - Andrew Belmont (University of Illinois) - "Large-scale chromatin structure and dynamics"
- 10:00 AM - Barbara Trask (University of Washington) - "Gross structure of interphase chromosomes in human cells"
- 10:30 AM - COFFEE BREAK
- 11:00 AM - Lori Wallrath (University of Iowa) - "Position effect variegation at Drosophila telomeres"
- 11:30 AM - Carol Greider (Johns Hopkins University) - "The effects of telomerase loss in mammalian cells"
|
| Monday, June 22 (Evening) |
Session 3 - RNA Structure and Function |
Chair Olke Uhlenbeck (University of Colorado)
- 7:30 PM - Dan Hershlag (Stanford University) - "Investigations of RNA folding"
- 8:00 PM - John Abelson (Cal Tech) - "The structure and evolution of pre tRNA splicing endonuclease"
- 8:30 PM - Julie Faigen (UCLA) - "Folding motifs and Ion binding in DNA and RNA"
- 9:00 PM - COFFEE BREAK
- 9:35 PM - Adrian Ferre-D'Amare (Yale) - "Crystal structure of a hepatitis delta virus ribozyme"
- 10:00 PM - Tom Steitz (Yale) - "The 9 Å resolution X-ray crystallographic Map of the large ribosomal subunit"
|
| Tuesday, June 23 (Morning) |
Session 4 - Transcription |
Chair: Nouria Hernandez (Cold Spring Harbor Laboratory)
- 9:00 AM - Lucia Rothman-Denes (University of Chicago) - "Transcriptional activation by single-stranded DNA binding proteins"
- 9:25 AM - Nouria Hernandez (Cold Spring Harbor Laboratory) - "Transcription of the human snRNA genes by RNA polymerases II and III"
- 9:50 AM - David Price (University of Iowa) - "Control of the Elongation phase of transcription by RNA Polymerase II"
- 10:15 AM - COFFEE BREAK
- 10:40 AM - Ali Shilatifard (St. Louis University) - "The holo-ELL and the RNA polymerase II elongation complex"
- 11:10 AM - David Bentley (Amgen Institute-Toronto) - "The role of the pol II CTD in co-ordinating transcription with RNA processing"
- 11:35 AM - Shelley Berger (Wistar Institute) - "Functional Analysis of SAGA, an Adaptor/Histone Acetylation Complex in Yeast"
|
| Tuesday, June 23 (Evening) |
Session 5 - RNA Splicing and Processing |
Chair: Joan Steitz (Yale)
- 7:30 PM - Tamas Kiss (INSERM/ CNRS) - "Site-specific RNA modification within the nucleolus"
- 8:00 PM - Danny Morse (University of Utah) - "Systematic identification of substrates for adenosine deaminases that act on RNA (ADARs)"
- 8:30 PM - Phillip Sharp (MIT) - "Exon/Intron specificity for spliceosome formation and potential RNA catalysis in the spliceosome"
- 9:00 PM - COFFEE BREAK
- 9:30 PM - Christine Guthrie (U.C. San Francisco) - "RNA unwinding and re-winding: a DEAD-box RNA-dependent ATPase is required to displace U1 from the 5' splice site"
- 10:00 PM - Joan Steitz (Yale University) - "Biogenesis and functions of modified nucleotides in snRNAs"
|
| Wednesday, June 24 (Morning) |
Session 6 - DNA Replication |
Chair: Elizabeth Blackburn (U. C. San Francisco)
- 9:00 AM - Lorena Beese (Duke University) - "Observing replication in a catalytically active bacillus DNA polymerase crystal"
- 9:30 AM - Bruce Stillman (Cold Spring Harbor Laboratory) - "Chromatin replication in eukaryotic cells"
- 10:00 AM - Jim Champoux (University of Washington) - "Insights gained from the crystal structure of human topoisomerase I"
- 10:30 AM - COFFEE BREAK
- 11:00 AM - Elizabeth Blackburn (U. C. San Francisco) - "Actions of telomerase RNA in the telomerase ribonucleoprotein enzyme"
- 11:30 AM - Toru Nakamura (U. of Colorado-Boulder) - "Telomerase Reverse Transcriptase and how S. pombe survives without it"
|
| Wednesday, June 24 (Evening) |
Session 7 - Translation and Stability |
Chair: Harry Noller (U.C. Santa Cruz)
- 7:30 PM - Peter Sarnow (Stanford University) - "Cap-independent translation of eukaryotic mRNAs"
- 8:00 PM - Alan Sachs (U.C. Berkeley) - "Communication between messenger RNA 5' and 3' ends."
- 8:30 PM - Harry Noller (U.C. Santa Cruz) - "Position and movement of tRNA in the ribosome"
- 9:00 PM - COFFEE BREAK
- 9:30 PM - Paul Schimmel (Scripps) - "RNA dependent amino acid regulation in translational editing"
- 10:00 PM - Olke Uhlenbeck (U. of Colorado) - "A thermodynamic analysis of a translational repressor-operator interaction"
|
| Thursday, June 25 (Morning) |
Session 8 - DNA Recombination and Repair |
Chair: Marlene Belfort (Wadsworth Center- Albany)
- 9:00 AM - Nancy Craig (Johns Hopkins University) - "Controlling DNA Breakage and Joining"
- 9:30 AM - Kiyoshi Mizuuchi (NIH) - "Protein-DNA Assemblies and control in Phage Mu DNA Transposition"
- 10:00 AM - Marlene Belfort (Wadsworth Center- Albany) - "Mechanisms of intron mobility"
- 10:30 AM - COFFEE BREAK
- 11:00 AM - Rodney Rothstein (Columbia University) - "DNA Damage Repair and Recombination in Saccharomyces cerevisiae"
- 11:30 AM - Martin Gellert (NIH) - "Relation of V(D)J recombination to transposition and double-strand break repair"
|
| Thursday, June 25 (Evening) |
Session 9 - RNA Transport and Localization |
Chair: Gideon Dreyfuss (HHMI/Univ. of Pennsylvania School of Medicine)
- 7:30 PM - Gideon Dreyfuss (HHMI/Univ. of Pennsylvania School of Medicine) - "Multiple pathways for nuclear and import of proteins and RNAs"
- 8:00 PM - Charles Cole (Dartmouth University) - "Defining the proteins needed for RNA export in yeast"
- 8:30 PM - James Dahlberg (University of Wisconsin-Madison) - "Proofreading during RNA export"
- 9:00 PM - COFFEE BREAK
- 9:30 PM - Bertil Daneholt (Karolinska Institutet) - "The intranuclear flow of a specific pre-mRNP particle"
- 10:00 PM - Robert Singer (Albert Einstein College of Medicine) - "An actomyosin system for mRNA transport"
|
