Conference Description
The Nucleic Acids GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.
The Nucleic Acids GRC has a long and distinguished history as an incubator for groundbreaking discoveries that have revolutionized molecular biology and medical research—including recombinant DNA technologies such as restriction endonucleases and CRISPR, and worldwide transformative therapies such as mRNA-based COVID-19 vaccines. The 2025 Nucleic Acids GRC will continue this tradition by focusing on the latest and most exciting discoveries related to the molecular mechanisms underlying all aspects of nucleic acid biology, including maintenance and decoding of genetic information and the distinct functions of RNA and DNA in cellular metabolism. Thematic oral and poster sessions will feature work on the structure, function, modification, and regulation of DNA and RNA, with an emphasis on the macromolecular enzyme complexes that carry out critical nucleic acid transactions, including DNA replication, repair, recombination, transcription, translation, and trafficking. Chemical, structural, and biophysical methodologies at both molecular and cellular scales will feature prominently throughout the conference. In addition, recent advances in new therapeutic technologies have revolutionized how we study and apply our knowledge of nucleic acid processes to solve the world’s greatest challenges. Attendees will engage in discussions about how these tools are being deployed to understand the dynamic nature of the genome and transcriptome and how cells respond to DNA and RNA based stresses during infection and disease.
The GRC will feature presentations by a diverse collection of the leading established and early-career scientists, and thus submission of abstracts for consideration for highlight talks is highly encouraged. As an added attraction for young scientists, this meeting will feature an associated 2025 Nucleic Acids Gordon Research Seminar (GRS), held on June 21-22, just before the main GRC. The GRS is a valuable forum for students and postdocs to present their research, broaden their scientific networks, and explore new directions in science and professional development.
The topics, speakers, and discussion leaders for the conference sessions are displayed below. The conference chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by February 22, 2025. Please check back for updates.
Keynote Session: Frontiers in Nucleic Acid Biology
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Maintenance of Genome Integrity
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Machines Involved in Gene Expression
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Engineering and Modification of Nucleic Acids to Affect Function
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Nucleic Acids in Infection and Immunity
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Novel Chemistry for Shaping the Genome
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Genome Organization and Remodeling
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Assembly and Coordination of the Dynamic Replisome
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Looking at Nucleic Acid Machines From New Perspectives
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The GRC Power Hour™
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