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Nucleic Acids (GRS)

Gordon-Kenan Research Seminar

Mechanistic Insights into RNA and DNA Processes Throughout Biology

June 3 - 4, 2017
Chairs and

Conference Description

The Gordon Research Seminar on Nucleic Acids is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas on all aspects of the biology and chemistry of Nucleic Acids. The relaxed and sociable atmosphere of the meeting provides a unique environment for extended scientific discussion and interactions.

The 2017 Nucleic Acids GRS will include a keynote talk by Jonathan Weissman (University of California, San Francisco/HHMI), a featured talk by Karen Cone (Program Director, Division of Molecular & Cellular Biosciences) of the National Science Foundation, as well as three platform sessions with a total of 10-15 talks selected from abstracts, and two poster sessions. Sessions will be chaired by selected students/postdocs.

Related Meeting

This GRS will be held in conjunction with the "Nucleic Acids" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Mechanistic Insights into RNA and DNA Processes
Discussion Leader:
3:45 pm - 3:55 pm
"The End Is in Sight - Mechanisms of Termini-Dependent Recognition and Cleavage by Dicer"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 4:10 pm
"Mechanism of Co-Transcriptional DNA and RNA Targeting by a Type III-A CRISPR-Cas Complex"
4:10 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
"Taking a Break: How a Transcription Factor Helps RNA Polymerase to Pause During Transcription"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
DNA and RNA Biology and Applications to Human Disease
Discussion Leaders: and
7:30 pm - 7:40 pm
"Human Pathogenic tRNA Mutations Influence 5'-End tRNA Processing in the Mitochondria"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Defining Mechanisms that Maintain Reading Frame in Eukaryotic Translation"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Global mRNA Polarization in the Intestinal Epithelium Regulates Translation Efficiency"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"Innate Immune Endoribonuclease RNase L Balances Between Proliferation Control and Apoptosis Based on dsRNA Load"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Aberrant Splicing in B-Cell Acute Lymphoblastic Leukemia"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Fluorescent Amplification of Individual mRNAs in Single Cells"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"The DNA Repair Repertoire of Mycobacterium smegmatis FenA Includes the Incision of DNA 5' Flaps and the Removal of 5' Adenylylated Products of Aborted Nick Ligation"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"The Role of KU Proteins in Genome Maintenance and Programmed Genome Rearrangement in the Ciliate Oxytricha trifallax"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Specificity and Structure in Nucleic Acid Processes
Discussion Leaders: and
9:00 am - 9:10 am
"Extracellular-Enriched tRNA Halves Assemble into Nuclease-Resistant Oligomers with Potent Immunostimulatory Activity"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
"A Family Expands: Characterization of Human TRMT10B, a Multifunctional tRNA Methyltransferase"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Substrate Recognition by Arabidopsis Proteinaceous RNase P Isoenzymes: Insights into Catalysis"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Evolutionary Divergence of IRE1 RNase Specificity Shapes the Unfolded Protein Response"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
"High-Throughput Mutational Analysis of the Glycine Riboswitch by Sequencing"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Characterization of Cotranscriptional RNA Structure Using SHAPE-Seq"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
"How Does Transcription Avoid Roadblocks?"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
"Tel1(ATM) and Mec1(ATR) Domain Swaps in S. cerevisiae to Distinguish Telomere Length and DNA Damage Functions"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Development and Mentorship
Discussion Leaders: and
1:30 pm - 1:50 pm
"How to Get Funded by the National Science Foundation"
1:50 pm - 2:00 pm
Discussion
2:00 pm - 2:20 pm
"Now What? Taking the Next Steps Towards Your Career in Science"
2:20 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes

Contributors

Conference Links

Conference History Nucleic Acids
Additional Fee Info

Nucleic Acids
June 22 - 27, 2025


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