| Saturday |
| 2:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Keynote Session: Mechanisms of DNA Recombination |
| Discussion Leaders: Rodrigo Ducati (Albert Einstein College of Medicine, USA) and Mindy Graham (Johns Hopkins University, USA) |
| 3:45 pm - 4:20 pm | Eric Greene (Columbia University, USA)
"Single-Molecule Studies of DNA Recombination" |
| 4:20 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Nucleic Acids as Sensors and Beacons |
| Discussion Leader: Myles Poulin (Albert Einstein College of Medicine, USA) |
| 7:30 pm - 7:50 pm | Benjamin Luby (University Health Network, Canada)
"Amplified Detection of miRNA by microRNA:Argonaute2 Cleavage (miRACle) Beacons for Denotation of Cell Identity Changes During Stem Cell Reprogramming" |
| 7:50 pm - 7:55 pm | Discussion |
| 7:55 pm - 8:15 pm | Xin Wang (University of California, Berkeley, USA)
"Next-Generation RNA-Based Fluorescent Biosensors for Detection of Cyclic di-Guanosine in Anaerobic Conditions" |
| 8:15 pm - 8:20 pm | Discussion |
| 8:20 pm - 8:40 pm | Alexandra Rangel (University of Utah, USA)
"Developing and Exploring the Substrate Scope of a Self-Alkylating Ribozyme for Fluorescent mRNA Labeling" |
| 8:40 pm - 8:45 pm | Discussion |
| 8:45 pm - 9:05 pm | Arun Richard Chandrasekaran (University at Albany, State University of New York, USA)
"A DNA Nanoswitch for the Detection and Analysis of Specific Nucleic Acid Sequences" |
| 9:05 pm - 9:10 pm | Discussion |
| 9:10 pm - 9:25 pm | Trevor Feagin (University of Utah, USA)
"High-Throughput Enantiopurity Analysis Using Enantiomeric DNA-Based Sensors" |
| 9:25 pm - 9:30 pm | Discussion |
| Sunday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Structural and Binding Studies of Nucleic Acids |
| Discussion Leader: Paritosh Pande (University of Connecticut, USA) |
| 9:00 am - 9:20 am | Zhen Wang (Albert Einstein College of Medicine, USA)
"Quantum Mechanical Modeling of Human DNA Methyltransferase I to Design Strong Transition State Analogue Inhibitors" |
| 9:20 am - 9:25 am | Discussion |
| 9:25 am - 9:45 am | Stacey Barnaby (Northwestern University, USA)
"Tuning the Oligonucleotide 'Bond' Composition from DNA to RNA in Nanoparticle Superlattices" |
| 9:45 am - 9:50 am | Discussion |
| 9:50 am - 10:10 am | Jessica Wynn (Virginia Polytechnic Institute and State University, USA)
"‘Rev’olutionary Library Containing Unnatural Amino Acids: Functionalizing Branched Peptides Toward Targeting Folded RNA Structures" |
| 10:10 am - 10:15 am | Discussion |
| 10:15 am - 10:35 am | Jennifer Rabb (Massachusetts Institute of Technology, USA)
"Structural Studies of the Oxetanocin Biosynthetic Enzyme OxsA Reveal Determinants for Substrate Binding and Catalysis" |
| 10:35 am - 10:40 am | Discussion |
| 10:40 am - 10:55 am | Karen Kormuth (Carnegie Mellon University, USA)
"PNA Hybridization to Noncanonical G-Quadruplexes" |
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Mentorship Component: Career Development |
| For the conclusion of our meeting, we will have a
one-hour mentorship component with a panel focused on Career Development.
This panel will include our keynote speaker, as well as representatives
for careers outside academia. |
| Discussion Leader: Muthiah Manoharan (Alnylam Pharmaceuticals, USA) |
| 1:30 pm - 1:45 pm | Eric Greene (Columbia University, USA)
"The Challenges of a Career in Science" |
| 1:45 pm - 1:50 pm | Discussion |
| 1:50 pm - 2:05 pm | Joerg Schlatterer (National Science Foundation, USA)
"Li and Le: Navigating a Career in STEM" |
| 2:05 pm - 2:10 pm | Discussion |
| 2:10 pm - 2:25 pm | Randy Kipp (Novartis Institutes for Biomedical Research, USA)
"Opportunities and Road Blocks Toward the Beginning of a Career in Industry" |
| 2:25 pm - 2:30 pm | Discussion |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
| 3:00 pm | Seminar Concludes |
