SUNDAY |
2:00 pm - 11:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | New Methods and Synthesis I |
| Discussion Leader: Jean Suffert (Université Louis Pasteur de Strasbourg) |
7:40 pm - 8:00 pm | Jennifer Albaneze-Walker (Schering-Plough) "Imidazolylsulfonates: Electrophilic Partners in Cross-Coupling Reactions" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:30 pm | Jingjun Yin (Merck) "A Practical Asymmetric Synthesis of A Complex Drug Candidate" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:25 pm | Paul Wender (Stanford University) "From Theory to Therapy: New Reactions, Step Economy, and Function Oriented Synthesis Directed at AIDS Latent Virus, Cognitive Dysfunction and Cancer Resistance" |
9:25 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 10:40 am | Novel Strategies for Catalysis I |
| Discussion Leader: Jennifer Love (University of British Columbia) |
9:00 am - 9:45 am | Cathleen Crudden (Queen’s University) "Chemistry and catalysis with phosphine and N-heterocyclic carbene complexes of Rhodium" |
9:45 am - 9:55 am | Discussion |
9:55 am - 10:30 am | Xumu Zhang (Rutgers University) "Development of Practical Asymmetric Hydrogenation and Hydroformylation Reactions" |
10:30 am - 10:40 am | Discussion |
10:40 am - 11:00 am | Coffee Break |
11:00 am - 12:30 pm | New Methods for Asymmetric Synthesis I |
| Discussion Leader: Richard Pariza (Cederburg Pharmaceuticals)
|
11:00 am - 11:50 am | Mukund Sibi (North Dakota State University) "Templates, Templates, and Templates: How May I Help You?" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Nicholas Magnus (Eli Lilly) "Development of an Asymmetric Aryl Transfer Process" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session I |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Novel Strategies for Catalysis II |
| Discussion Leader: Jackie Milne (Amgen) |
7:30 pm - 7:50 pm | Liming Zhang (University of Nevada Reno) "Au-Catalyzed Cycloaddition and Annulation Reactions" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Yi-Yin Ku (Abbott Laboratories) "Process Research of an Efficient Synthesis for a Abbott Drug Target" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 9:20 pm | Yoshinori Yamamoto (Tohoku University) "Coinage Metal Catalyzed New Reactions" |
9:20 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 10:40 am | New Methods and Synthesis II |
| Discussion Leader: Norma Tom (Exelixis)
|
9:00 am - 9:45 am | Kay Brummond (University of Pittsburgh) "Exploiting Allenes in the Construction of Challenging Functional Motifs" |
9:45 am - 9:55 am | Discussion |
9:55 am - 10:30 am | Robert Maleczka (Michigan State University) "Catalytic Borylation/Cross-Coupling Protocols that Avoid the Preparation of Haloaromatics" |
10:30 am - 10:40 am | Discussion |
10:40 am - 11:00 am | Coffee Break |
11:00 am - 12:30 pm | Organometallic Reactions and Green Methods |
| Discussion Leader: Jon Antilla (University of South Florida) |
11:00 am - 11:20 am | Helena Malinakova (University of Kansas) "Allylpalladium Umpolung Strategy for Multicompoment Coupling Reactions" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Chutian Shu (Boehringer Ingelheim) "RCM Macrocyclization at Practical Conditions: An Efficient Synthesis of HCV Protease Inhibitor BILN 2061" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Wei Wang (University of New Mexico) "Organocatalytic Enantioselective Cascade Reactions" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 6:00 pm | Free Time |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | New Methods for Asymmetric Synthesis II |
| Discussion Leader: Terry Rathman (T-Links) |
7:30 pm - 7:50 pm | Kazunori Koide (University of Pittsburgh) "Life After Pd-Catalyzed Reactions: Detecting Residual Pd Based on Synthetic Organic Chemistry" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Surendra Singh (Sepracor) "Development of a Scaleable Catalytic Asymmetric Hydrogenation Based Process" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 9:20 pm | Takashi Ohshima (Osaka University) "Development of New Direct Catalytic Reactions Using Tetranuclear Zinc Clusters" |
9:20 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 10:40 am | New Methods and Synthesis III |
| Discussion Leader: Michael Dappen (Elan Pharmaceuticals) |
9:00 am - 9:45 am | Michael Krische (University of Texas - Austin) "Formation of C-C Bonds via Catalytic Hydrogenation and Transfer Hydrogenation" |
9:45 am - 9:55 am | Discussion |
9:55 am - 10:30 am | Corinne Aubert (Université Pierre et Marie Curie) "Recent Developments in the Cobalt Mediated Cyclizations" |
10:30 am - 10:40 am | Discussion |
10:40 am - 10:55 am | Coffee Break |
10:55 am - 11:00 am | Business Meeting |
| (Nominations for the next Vice Chair) |
11:00 am - 12:30 pm | New Methods and Synthesis IV |
| Discussion Leader: Guijun Wang (University of New Orleans) |
11:00 am - 11:20 am | Scott Schaus (Boston University) "Asymmetric Boronate Reactions: Condensations, Rearrangements, and Catalysis" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Lori Spangler (Bristol-Meyers Squibb) "The Brivanib Process: Route Selection and Strategic Development" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Sheryl Wiskur (University of South Carolina) |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session II |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Novel Strategies for Catalysis III |
| Discussion Leader: Douglas Frantz (UT Southwestern Medical Center) |
7:30 pm - 7:50 pm | Forrest Michael (University of Washington) "Transition metal-catalyzed amination reactions: New methods and new mechanisms" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Tom Colacot (Johnson Matthey) "Tunable Palladium-Phosphine Based Catalysts and Their Structure Activity Relationship in Cross Coupling Reactions" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 9:20 pm | Benjamin List (Max Planck Institute) "New Concepts for Catalysis" |
9:20 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 10:40 am | New Methods and Synthesis V |
| Discussion Leader: Sriram Naganathan (Exelixis) |
9:00 am - 9:45 am | Richard Hsung (University of Wisconsin) "Progress Toward a Total Synthesis of Phomactin A" |
9:45 am - 9:55 am | Discussion |
9:55 am - 10:30 am | Vladimir Gevorgyan (University of Illinois - Chicago) "New Approaches for Construction of Densely-Substituted Heterocycles" |
10:30 am - 10:40 am | Discussion |
10:40 am - 11:00 am | Coffee Break |
11:00 am - 11:30 am | Business Meeting |
| (Election of the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences) |
11:30 am - 12:30 pm | Best of the Posters Presentations |
| Discussion Leader: Yannis Houpis (Johnson & Johnson) |
11:30 am - 11:45 am | Poster Presentation 1: Albert DelMonte (Bristol-Myers Squibb) "Kilogram Synthesis of a LFA-1/ICAM Inhibitor" |
11:45 am - 11:50 am | Discussion |
11:50 am - 12:05 pm | Poster Presentation 2: Kanyiva Stephen Kyalo (Kyoto University) "Nickel/Lewis Acid Catalyzed Hydroheteroarylation and Hydrocarbamoylation of Unsaturated Bonds" |
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | Poster Presentation 3: André Beauchemin (University of Ottawa) "Simple Cope-Type Hydroamination of Alkenes and Alkynes" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 6:00 pm | Free Time |
4:00 pm - 6:00 pm | Optional Chair's Wine and Cheese Reception |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Chemistry of Wine Oxidation |
| Discussion Leader: Jerry Murry (Amgen) |
7:30 pm - 7:50 pm | Pascal Dube (Pfizer) "Nucleophile-Catalyzed Lossen Rearrangement" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Christian Schafmeister (Temple University) "Exploiting anchimeric assistance in the synthesis of extremely hindered peptides and functionally crowded nanostructures" |
8:20 pm - 8:30pm | Discussion |
8:30 pm - 9:20 pm | Andrew Waterhouse (University of California Davis) "Wine Oxidation: Exploring the Reactions" |
9:20 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |