SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Modern Catalytic Methods |
| Discussion Leader: Todd Nelson (WuXi AppTec) |
7:40 pm - 8:20 pm | Michael Doyle (University of Maryland)
"Catalyst-Directed Diverse Outcomes - The Synthesis and Reactions of Diazo Compounds is the Next Chapter"
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8:20 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | Christina White (University of Illinois at Urbana-Champaign)
"C-H Oxidations for Complex Molecule Synthesis"
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9:15 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 11:10 am | Process Research in Organic Synthesis |
| Discussion Leader: Kristin Price (Pfizer) |
9:00 am - 9:30 am | Chris Sfouggatkis (BMS)
"Discovery and Development of a Stereoselective Synthesis of BMS-986001: A Nucleoside Reverse Transcriptase Inhibitor (NRTI) for the Treatment of HIV Infection"
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9:30 am - 9:35 am | Discussion |
9:35 am - 10:05 am | Adam Burrell (Pfizer)
"Voriconazle API: A Journey from Six Steps to Two"
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10:05 am - 10:15 am | Discussion |
10:15 am | Coffee Break |
10:30 am - 11:00 am | Jacqueline Milne (Amgen)
"Process Development of an Active Pharmaceutical Ingredient"
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11:00 am - 11:10 am | Discussion |
11:10 am - 12:30 pm | Novel Reaction Chemistry |
| Discussion Leader: Ampofo Darko (University of Tennessee) |
11:10 am - 11:40 am | Uttam Tambar (UT Southwestern)
"Selective Functionalization of Unsaturated Hydrocarbons"
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11:40 am - 11:50 am | Discussion |
11:50 am - 12:20 pm | Ohyun Kwon (UCLA)
"Phosphines and Their Reactions"
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12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Complex Molecular Synthesis |
| Discussion Leader: Jimmie Weaver (Oklahoma State) |
7:30 pm - 8:10 pm | Richmond Sarpong (University of California Berkeley)
"Strategies and Tactics for Chemical Synthesis Inspired by Complex Alkaloids"
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8:10 pm - 8:30 pm | Discussion |
8:30 pm - 9:10 pm | Jeff Johnson (University of North Carolina)
"Development of New Catalytic Reactions for Organic Synthesis"
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9:10 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 10:30 am | Industrial Process Development |
| Discussion Leader: Debra Wallace (Merck and Co) |
9:00 am - 9:30 am | Ben Sherry (Merck)
"The Novel Synthetic Approaches to Drug Candidates"
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9:30 am - 9:35 am | Discussion |
9:35 am - 10:05 am | Tom Stevenson (DuPont Crop Protection)
"New Molecules for Crop Protection"
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10:05 am - 10:15 am | Discussion |
10:15 am | Coffee Break |
10:30 am - 12:30 pm | Novel Transition Metal Processes |
| Discussion Leader: Jeremy May (University of Houston) |
10:30 am - 11:10 am | Takashi Ooi (Nagoya University)
"Ion-Pairing in Ligand Design for Asymmetric Transition-Metal Catalysis"
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11:10 am - 11:20 am | Discussion |
11:20 am - 12:00 pm | Tom Rovis (Colorado State University)
"Rh(III) Catalysis for C-H Activation"
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12:00 pm - 12:20 pm | Discussion |
12:20 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Efficient Strategies Towards Complex Molecules |
| Discussion Leader: Jenn Stockdill (Wayne State) |
7:30 pm - 8:10 pm | Matthew Gaunt (University of Cambridge)
"New Activation Modes for Palladium C-H Bond Activation in Aliphatic Amines"
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8:10 pm - 8:30 pm | Discussion |
8:30 pm - 9:10 pm | Matthew Sigman (University of Utah)
"Controlling and Analyzing Selectivity in Asymmetric Catalysis"
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9:10 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:10 am | Discovery of New Methodologies and Processes |
| Discussion Leader: Stan McHardy (University of Texas at San Antonio) |
9:00 am - 9:30 am | Remy Angelaud (Genetech)
"Manufacturing and Control Strategy of the Hedgehog Pathway Inhibitor Erivedge® (Vismodegib)"
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9:30 am - 9:35 am | Discussion |
9:35 am - 10:05 am | Anita Mattson (Ohio State University)
"Boronate Urea Activation of Diazo Compounds"
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10:05 am - 10:15 am | Discussion |
10:15 am | Coffee Break |
10:30 am - 11:00 am | Silas Cook (Indiana University)
"New Opportunities in Base-Metal Catalysis"
|
11:00 am - 11:10 am | Discussion |
11:10 am - 12:30 pm | Drug Discovery and Chemical Biology |
| Discussion Leader: Nikki Goodwin (Lexicon)
"Drug Discovery and Chemical Biology"
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11:10 am - 11:40 am | Julia Clay (Lilly)
"Open Innovation Drug Discovery at Lilly: A Unique Approach to Developing Collaborations"
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11:40 am - 11:50 am | Discussion |
11:50 am - 12:20 pm | Marc Robillard (Tagworks Pharmaceuticals, Netherlands)
"In Vivo Chemistry for Cancer Imaging and Therapy
|
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | New Avenues in Catalysis |
| Discussion Leader: Don Watson (University of Delaware) |
7:30 pm - 8:10 pm | Greg Dudley (Florida State University)
"Selective Microwave Heating of Chemical Reactions"
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8:10 pm - 8:30 pm | Discussion |
8:30 pm - 9:10 pm | Vy Dong (University of California, Irvine)
"Recent Advances in Stereoselective Hydroacylation"
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9:10 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 10:30 am | Large Scale Organic Synthesis |
| Discussion Leader: Sonia Rodriguez (Boehringer-Ingelheim) |
9:00 am - 9:30 am | Yi-Yin Kun (Abbvie)
"Process Research and Development for a HCV Drug Candidate"
|
9:30 am - 9:35 am | Discussion |
9:35 am - 10:05 am | Alex Radosevech (Penn State Univeristy)
"Synthetic Methods Based on Catalytic P(III)⇄P(V) Redox Cycling"
|
10:05 am - 10:15 am | Discussion |
10:15 am | Coffee Break |
10:30 am - 12:30 pm | Selected Poster Presentations |
| Discussion Leader: Jared Piper (Eli Lilly and Company) |
10:30 am - 11:10 am | TBA (Poster Talk) |
11:10 am - 11:15 am | Discussion |
11:15 am - 11:35 am | TBA (Poster Talk) |
11:35 am - 11:40 am | Discussion |
11:40 am - 12:00 pm | TBA (Poster Talk) |
12:00 pm - 12:05 pm | Discussion |
12:05 pm - 12:25 pm | TBA (Poster Talk) |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Palladium Catalysis and Green Chemistry |
| Discussion Leader: Jade Nelson (Pfizer) |
7:30 pm - 8:10 pm | Gojko Lalic (University of Washington)
"Development of Practical Transition-Metal Catalyzed Transformations"
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8:10 pm - 8:30 pm | Discussion |
8:30 pm - 9:10 pm | Mike Krische (University of Texas at Austin)
"Formation of C-C Bonds via Catalytic Hydrogenation and Transfer Hydrogenation"
|
9:10 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |