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Parasitism

Gordon Research Conference

Host-Parasite Interaction

June 20 - 25, 1999
Chair John C. Boothroyd
Vice Chairs Norma W. Andrews
Salve Regina University
100 Ochre Point Avenue
Newport, Rhode Island, United States
 Venue and Travel Information

Conference Description

Welcome! This web site presents the program for the 1999 Gordon Conference in Parasitism. We have a great site for this meeting - Salve Regina College is a small college in Newport, Rhode Island with excellent facilities and right on the ocean. More importantly, the program is an excellent group of speakers who will present their very latest research on the theme of "Host-Parasite Interaction". Attendees at all levels are most welcome to attend. All talks will be 25 minutes with 10 minutes for discussion - there will be a total of 5 talks in the morning session and 4 in the evening. Hope to see you there!

Conference Program

Sunday, June 20
2:00 p.m. Registration Opens
6:00 p.m. Dinner
I. Genetics of Susceptibility to Parasites in the Mammalian Host and Insect Vector
7:30 - 10:10 p.m.
  • Session Chair: Alain Dessein - Genetics as a tool to identify the critical steps of pathogenesis in human schistosomiasis
  • Simon Foote - Synergy between loci modifying host responses to malaria and Leishmania
  • Erwin Schurr - Genetic determinants of host resistance to tuberculosis and leprosy
  • Bruce Christensen - Mosquitoes, immune peptides, and parasites - making mosquitoes do the right thing
Monday, June 21
7:30 a.m. Breakfast
II. Genetics and Biochemistry of Drug Action and Resistance
9:00 a.m. - 12:15 p.m.
  • Session Chair: Dyann Wirth - ABC transporters and drug resistance
  • Meg Phillips - Structure/function analysis of Trypanosoma brucei ornithine decarboxylase
  • Steve Beverley - Divergent evolution of pteridine uptake and metabolism in Leishmania
  • Pradip Rathod -Accelerated drug resistance in Plasmodium falciparum
  • Doris Cully - Glutamate-gated chloride channels as targets for anthelmintics and insecticides
12:30 p.m. Lunch
2:00 - 6:00 p.m. free time
6:00 p.m. Dinner
III. First contact: Host/Vector/Parasite Interactions and Mechanisms of Innate Immunity
7:30 - 10:10 p.m.
  • Session Chair: Etienne Pays - What can you do with a VSG?
  • Karen Norris - Parasite interference with host Innate immunity: Complement resistance in Trypanosoma cruzi
  • David Sacks - Molecules controlling vector/parasite and vector/host interactions in leishmaniasis
  • Carolina Barillas - Signaling path ways and cell biology of mosquito responses to Plasmodium: If the vector responds, why is parasite transmission still taking place?
Tuesday, June 22
7:30 a.m. Breakfast
IV. Parasite-induced Changes in Host Cells
9:00 a.m. - 12:15 p.m.
  • Session Chair: Keith Joiner - Rhoptry protein targeting: literal and figurative connections to the host cell
  • David Hackam - Membrane traffic and phagosome formation
  • Michel Desjardins - A proteomic approach to study host-pathogen interaction and phagolysosome biogenesis during Leishmania infection
  • Norma Andrews - Lysosomes and trypanosomes: the regulation of exocytosis and cell invasion
  • Dan Friend - Response to Trichinella spiralis Infection - mast cells, eosinophils and lymphocytes
12:30 p.m. Lunch
2:00 - 5:00 p.m. free time
5:00 6:00 p.m. Poster Session I
6:00 p.m. Dinner
V. Novel Organelles
7:30 - 10:10 p.m.
  • Session Chair: Patricia Johnson - Evolutionary origins of hydrogenosomes and mitochondria
  • David Roos - The mystery of the apicoplast -- Where does it come from? What does it do?
  • Marilyn Parsons - Genetic analysis of Leishmania glycosomes
  • Dan Goldberg - Hemoglobin degradation in the Plasmodium food vacuole
Wednesday, June 23
7:30 a.m. Breakfast
VI. Mechanisms of Acquired Immunity and Parasite Clearance
9:00 a.m. - 12:15 p.m.
  • Session Chair: Lloyd Kasper - Mucosal immunity in toxoplasmosis
  • Tom Wynn - Solving the Puzzle: Can knockout mice elucidate the mechanisms of vaccine-induced resistance to Schistosoma mansoni?
  • Rick Maizels - New genes in immune evasion and new candidates for vaccines
  • Elizabeth Nardin - The role of HLA and adjuvant in the human response to synthetic peptide malaria vaccines
  • Rick Tarleton - CD8+ T Cell Responses and Vaccine Discovery in Trypanosoma cruzi
12:30 p.m. Lunch
2:00 - 5:00 p.m. free time
5:00 6:00 p.m. Poster Session II
6:00 p.m. Dinner
VII. Oral Presentations of Selected Abstracts
7:30 - 10:10 p.m. 6 x 12 min. each + 3 min. discussion; Norma Andrews to Chair; posters selected by Session Chairs before meeting, based on abstracts
Thursday, June 24
7:30 a.m. Breakfast
VIII. Attachment, Invasion and Intracellular Life
9:00 a.m. - 12:15 p.m.
  • Session Chair: Bill Petri - New insights into adherence and cell killing by Entamoeba histolytica
  • John Adams - Expression and function of malaria merozoite adhesion molecules
  • Kasturi Haldar - Modifications in erythrocyte structure induced by the human malaria parasite Plasmodium falciparum
  • Judy Appleton - Making a living in the intestine: Invasion of epithelia by Trichinella spiralis
  • John Boothroyd - Genetic analysis of calcium-induced egress in Toxoplasma
12:30 p.m. Lunch
2:00 - 6:00 p.m. free time
6:00 p.m. Banquet
IX. Evasion of Host Immune Response
7:30-10:10 p.m.
  • Session Chair: Tom Wellems - Epigenetics and transcription switches in the antigenic variation of Plasmodium falciparum
  • Chris Newbold - Antigenic variation in malaria. molecules, mechanisms and function
  • Ted Nash - Antigenic variation in Giardia - It's not like it appears
  • Stuart Kahn - The CD4 T-cell response to the variant surface protein superfamily of Trypanosoma cruzi
10:10 p.m. - 1:00 a.m. Party
Friday, June 25
7:30 a.m. Breakfast
9:00 p.m. Conferees Depart

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Conference History
Additional Fee Info

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