- The Zanvil Cohn Lecturer: Marco Baggiolini, Ph.D. (Ticino, Switzerland)
Fifty chemokines and twenty receptors all for leukocytes
- Phil Murphy (Bethesda, USA)
Evolution of phagocyte chemotactic receptors
- Peter Hoffman
Role of the phosphatidylserine receptor in dendritic cell function
| Monday AM | Host-pathogen interactions |
Chair: Jerrold P. Weiss (Iowa City, USA)
- Arturo Zychlinsky (New York, USA)
Phagocytes and enteric pathogens
- Michele Swanson (Ann Arbor, USA)
Legionella's Strategy for Survival in Macrophages
- Isabelle Maridonneau-Parini (Toulouse, France)
Biogenesis of phagolysosomes : receptors and mycobacteria
- Neil Reiner (Vancouver, Canada)
Identification and characterization of a macrophage SHP-1 activator from Leishmania
- Lee-Ann Allen
A novel pathway for the phagocytosis of Helicobacter pylori
| Monday PM | Cytoskeletal regulation |
Chair: Thomas P. Stossel (Boston, USA)
- Gary Bokoch (La Jolla, USA)
Rho GTPases in the chemotactic responses of neutrophils
- Michael Glogauer (Boston, USA)
The role of filamin A in neutrophil function
- Isabel Olazabal (Birmingham, England)
Role of the Arp2/3 complex in actin cytoskeletal rearrangements during phagocytosis
| Tuesday AM | The nonphagocyte NAD(P)H oxidases |
Chair: Bernard M. Babior (La Jolla, USA)
- J. David Lambeth (Atlanta, USA)
The Nox family of gp91 phox homologs
- Karl-Heinz Krause (Geneva, Switzerland)
Phox begets Nox: Novel NADPH oxidases
- Toren Finkel (Bethesda, USA)
Signaling by oxygen radicals in non-phagocytic cells
- H. Frank Bunn (Boston, USA)
Cytb/b5R, a novel flavoheme protein which may function as a universal oxygen sensor
- Frank DeLeo
Evasion of human innate immunity by a bacterial homologue of CD11b that inhibits opsonophagocytosis
| Tuesday PM | Clinical extensions |
Chair: Harry Malech (Bethesda, USA)
- Mary Dinauer (Indianapolis, USA)
Chronic Granulomatous Disease: Lessons from murine models
- Alan Cross (Maryland, USA)
Immunotherapy of Sepsis: Waiting for Godot?
- Steve Holland (Bethesda, USA)
Mycobacteria, macrophages, and the interferon gamma pathways
| Wednesday AM | Intracellular signaling |
Chair: Robert A. Clark (San Antonio, USA)
- Linda McPhail (Winston-Salem, USA)
Regulation of NADPH oxidase activation by phospholipase D
- Edgar Pick (Tel Aviv, Israel)
The reward of prenylation - Chaperoning of p67-phox to the membrane by Rac
- Emmanuelle Caron (London, England)
Small GTPases and the control of macrophage activation and phagocytosis
- Hideki Sumimoto (Kyushu, Japan)
Role of p40phox in activation of the phagocytes NADPH oxidase
| Wednesday PM | Epithelial cell transmigration and termination of inflammation |
Chair: Sam Silverstein (New York, USA)
- Karl Matter (Geneva, Switzerland)
Epithelial tight junctions and regulation of leukocyte transmigration
- Peter Henson (Denver, USA)
Recognition and engulfment of apoptotic cells and cell debris. Mechanisms and consequences
- Gregory Downey (Toronto, Canada)
Neutrophil-induced induced injury to epithelium: Role of proteases
Chair: R. Alan Ezekowitz (Boston, USA)
- Eric Prossnitz (Albuquerque, USA)
Regulation of chemoattractant G protein-coupled receptors
- Roy Black (Seattle, USA)
Shedding of cell-surface proteins-physiological function and regulation
- Douglas Golenbock (Boston, USA)
Macrophage Toll-like receptors and the coordination of cytokine responses, phagocytosis and bacterial killing
SHORTS:
- Eric Brown
Role of L-plastin in neutrophil integrin function
- Roberta Weber
Phagocytosis without macrophages in the developing mouse embryo
- Roberto Botelho
Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosis
| Thursday PM | Applied proteomics and structural biology |
Chair: Alan Aderem (Seattle, USA)
- Michel Desjardins (Montréal, Canada)
A proteomic approach to study host-pathogen interaction
- Tim Griffin (Seattle, USA)
Recent advances in proteome characterization by mass spectrometry
- Al Jesaitis (Bozeman, USA)
Flavocytochrome b of neutrophils: structural insights
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