| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Evening Session |
| 7:30 pm - 8:00 pm | An Appreciation of Bernie Babior: John Curnutte (DNAX) |
| 8:00 pm - 8:30 pm | Bernie Babior (The Scripps Research Institute)
"Ozone, an unexpected product of neutrophils and antibodies" |
| 9:00 pm - 9:30 pm | Alan Ezekowitz (Massachusetts General Hospital for Children, Harvard)
"Phagocytosis" |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | PHAGOCYTOSIS |
| 9:00 am - 9:10 am | Discussion Leader: Tom Stossel (Brigham and Women's Hospital, Harvard) |
| 9:10 am - 9:45 am | Michel Desjardins (University of Montreal)
"ER-mediated phagocytosis: a new membrane for new functions" |
| 9:45 am - 10:20 am | Sergio Grinstein (The Hospital for Sick Children Research Institute, University of Toronto)
"Phosphoinositide metabolism and actin remodelling during phagocytosis" |
| 10:20 am | Coffee Break |
| 10:40 am - 11:15 am | John Hartwig (Brigham and Women's Hospital, Harvard)
"Taking the chill out of platelets: the mechanism and prevention of the phagocytosis of chilled platelets by macrophages" |
| 11:15 am - 11:50 am | Elena Levashina (Institute of Molecular and Cellular Biology in Strasbourg)
"Dissection of evolutionary conserved pathways of engulfment by dsRNA gene silencing in Anopheles gambiae" |
| 12:15 pm | Group Photo |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | KILLING MECHANISMS |
| 7:30 pm - 7:40 pm | Discussion Leader: Linda McPhail (Wake Forest University Baptist Medical Center) |
| 7:40 pm - 8:15 pm | David Lambeth (Emory School of Medicine)
"Biological Roles for Nox Enzymes: Signaling and Innate Immunity?" |
| 8:15 pm - 8:50 pm | Carl Nathan (Weill Medical College of Cornell University)
"Phagocyte as Foe: Novel Antioxidant Defenses of Mycobacteria" |
| 8:50 pm - 9:30 pm | Bob Munford (University of Texas Southwestern Medical Center at Dallas)
"Deacylation of LPS by phagocytes: now we know why!"
|
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | INNATE IMMUNITY |
| 9:00 am - 9:10 am | Discussion Leader: Chris Wilson (University of Washington) |
| 9:10 am - 9:45 am | Ruslan Medzhitov (Yale University of Medicine)
"Toll signaling and phagocytosis" |
| 9:45 am - 10:20 am | Bruce Beutler (The Scripps Research Institute)
"Germline mutagenesis in the study of innate immune signaling" |
| 10:20 am | Coffee Break |
| 10:40 am - 11:15 am | Richard Ulevitch (The Scripps Research Institute)
"Regulation of TLR expression: new surprises" |
| 11:15 am - 11:50 am | Gary Bokoch (The Scripps Research Institute)
"Molecular Basis for Adhesion Mediated Supression of Leukocyte NADPH Oxidase" |
| 11:50 am - 12:30 pm | Poster Presentations (2) |
| Terry Epperson (University of Texas HSC)
"Functional cytoplasmic domains of gp91phox and NOX1 - a comparative study using the p67phox/p47phox and NOXA1/NOXO1 cofactors" |
| Mary Stewart (MIT)
"Discrete p47phox and p40phox/p67phox complexes in the cytoplasm of resting neutrophils and contribution to the molecular basis of neutrophil priming" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | PHAGOCYTE RECEPTORS |
| 7:30 pm - 7:40 pm | Discussion Leader: Sam Silverstein (College of Physicians & Surgeons) |
| 7:40 pm - 8:15 pm | Siamon Gordon (Sir William Dunn School of Pathology, Oxford)
"'Macrophage receptors. Innate recognition of foreign and self ligands" |
| 8:15 pm - 8:50 pm | Jeff Ravetch (The Rockefeller University)
"Fc Receptors" |
| 8:50 pm - 9:30 pm | David Underhill (Institute for Systems Biology)
"Microbial Recognition by Toll-like receptors and Friends" |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | HOST-PATHOGEN INTERACTIONS |
| 9:00 am - 9:10 am | Discussion Leader: Mary Dinauer (Indiana University School of Medicine) |
| 9:10 am - 9:45 am | Michele Swanson (University of Michigan Medical School)
"Once bitten, twice sly: Legionella's survival strategy" |
| 9:45 am - 10:20 am | Arturo Zychlinsky (Max Planck Insitute for Infection Biology)
"Phagocytes in enteric infections" |
| 10:20 am | Coffee Break |
| 10:40 am - 11:15 am | Sam Miller (University of Washington)
"Salmonella resistance to innate immunity" |
| 11:15 am - 11:50 am | Emil Unanue (Washington University School of Medicine)
"Peptide-MHC complexes are generated by different pathways in phagocytes-their biological consequences" |
| 11:50 am - 12:30 pm | Poster Presentations (2) |
| Lee-Ann Allen (University of Iowa)
"Perturbation of NADPH oxidase activity and targeting by H. pylori" |
| Tsukasa Kawahara (Tokushima University)
"Molecular basis of induction and activation of Nox1 in gastric epithelial cells" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | INFLAMMATION AND INFLAMMATORY DISEASE |
| 7:30 pm - 7:40 pm | Discussion Leader: Bill Nauseef (University of Iowa) |
| 7:40 pm - 8:15 pm | Elaine Raines (University of Washington)
"Testing the Role of Extracellular Matrix Remodeling by Macrophages in the Pathogenesis of Atherosclerosis" |
| 8:15 pm - 8:50 pm | Jonathan Sedgwick (DNAX)
"'Modulating inflammation by triggering the myeloid inhibitory CD200-receptor in vivo'" |
| 8:50 pm - 9:30 pm | Peter Henson (National Jewish Medical Research Center)
"Mechanisms and consequences of apoptotic cell ingestion" |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | MEMBRANE TRAFFIC/CELL MIGRATION |
| 9:00 am - 9:10 am | Discussion Leader: Bill Muller (Weill Medical College of Cornell University) |
| 9:10 am - 9:45 am | Joel Swanson (University of Michigan Medical School)
"Phagosome Maturation in Macrophages" |
| 9:45 am - 10:20 am | Norma Andrews (Yale University of Medicine)
"Lysosomal exocytosis in membrane repair and pathogen killing" |
| 10:20 am | Coffee Break |
| 10:40 am - 11:15 am | Gwendalyn Randolph (Mount Sinai school of Medicine)
"Control of the migratory fate of monocyte-derived cells by lipid mediators" |
| 11:15 am - 11:50 am | Late Breaking Presentation |
| 11:50 am - 12:30 pm | Poster Presentations (2) |
| Keylon Cheeseman (Albany Medical College)
"Protein Kinase C- Epsilon, Mechanisms for Translocation" |
| Frank De Leo, Rocky Mountain Laboratories (NIAID, NIH)
"Insights into the Pathophysiology of Chronic Granulomatous Disease" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | EMERGING TECHNIQUES |
| 7:30 pm - 7:40 pm | Discussion Leader: John Curnutte (DNAX)
|
| 7:40 pm - 8:15 pm | Ruedi Aebersold (Institute for Systems Biology)
"Quantitative Proteomics: New Technologies and Applications" |
| 8:15 pm - 8:50 pm | Jim Heath (University of California, Los Angeles)
"NanoSystems Biology" |
| 8:50 pm - 9:30 pm | Gerard J. Nau, University of Pittsburgh
"Transcriptional Regulatory Circuitry in Host-Pathogen Interactions" |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
