| SATURDAY |
| 1:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Phagocytes in Inflammation |
| Discussion Leader: Christine Becker (Massachusetts General Hospital, MA, USA) |
| 3:45 pm - 4:00 pm | Guoxing Wang (Beth Israel Deconess Medical Center, MA, USA)
"Slamf8 is a novel homophilic cell surface receptor, which negatively regulates Nox2 activity and phagosome maturation in macrophages"
|
| 4:00 pm - 4:05 pm | Discussion |
| 4:05 pm - 4:20 pm | Yuan He (University of Michigan, MI, USA)
"TLR Agonists stimulate NLRP3-dependent IL-1 beta production independently of the purinergic P2X7 receptor in dendritic cells and in vivo"
|
| 4:20 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Host-Pathogen Interactions |
| Discussion Leader: Matthew Long (University of Iowa, IA, USA) |
| 7:30 pm - 7:50 pm | Mallary Greenlee (University of Iowa, IA, USA)
"Staphylococcus aureus evades neutrophil and macrophage-mediated immune responses"
|
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Ya-Ping Ko (Tamu Health Science Center, TX, USA)
"Phagocytosis escape by a bacterial protein that connects Complement and Coagulation proteins at bacterial surface"
|
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Natacha Steinckwich (NIH/NIEHS, USA)
"Role of STIM1 in neutrophil chemotaxis and their infiltration into psoriasis inflamed skin"
|
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Jenna Parks (University of Iowa, IA, USA)
"Mechanism of neutrophil apoptosis inhibition by Francisella tularensis"
|
| 9:20 pm - 9:30 pm | Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Phagosome Formation and Manipulation |
| Discussion Leader: Matthias Trost (University of Dundee, UK) |
| 9:00 am - 9:20 am | Daniel Schlam (The Hospital for Sick Children, Canada)
"Exploring the Rho GAPome: Orchestration of actin cytoskeletal dynamics during phagocytosis"
|
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Maria Podinovskaia (Cornell University, NY, USA)
"Mycobacterium tuberculosis infection induces global modifications to phagosomal function and lipid metabolism in macrophages"
|
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Denise Bronner (University of Michigan, MI, USA) |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am - 10:50 am | Harikesh Wong (The Hospital for Sick Children, Canada)
"CXCL3 enhances macrophage robbing and phagocytosis"
|
| 10:50 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Mentorship session: 'Trainees to Scientists - Roadmap for a successful Transition' |
| Discussion Leader: Lee-Ann Allen (University of Iowa, IA, USA) |
| 1:30 pm - 2:30 pm | Mentors:
- Paul Kubes (University of Calgary, Canada)
- Jonathan C. Kagan (Harvard Medical School, MA, USA)
|
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
| 3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |
