Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Cell Signaling in Phagocytes
Discussion Leader: Alan Hsu (Boston Children's Hospital, United States)
3:45 pm - 3:55 pm
Annalise Bond (University of California - Santa Barbara, United States)
"Optogenetic Control Over Phagocytosis Reveals Molecular Memory of Prior Fc Receptor Activation"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 4:10 pm
Amber De Visscher (KU Leuven, Belgium)
"STAT1 is Essential for the Expansion of Hepatic Monocyte & Macrophage Populations in Macrophage Activation Syndrome"
4:10 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
Lisa Khuu (University of Missouri, United States)
"Extended Lifespan and Atypical Death of Helicobacter pylori -Infected Human Neutrophils"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Host-Pathogen Interactions in Disease
Discussion Leader: Benjamin Winer (Memorial Sloan Kettering Cancer Center and University of California San Francisco, United States)
7:30 pm - 7:40 pm
Sana Shah (Manchester Metropolitan University, United Kingdom)
"Determining the Cellular and Molecular Mechanisms by which Biobran (MGN-3) Mediates Innate Immunity in a Hyperglycaemic Model of a Diabetic Foot Ulcer Infection."
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Alexis Duray (University of Pittsburgh School of Medicine, United States)
"Deletion of Nrf2 During Influenza-Staphylococcus aureus Super-Infection Leads to Increased Bacterial Burden"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Fethi Khiter (Center for Infection and Immunity of Lille - Research on Mycobacteria and Bordetella - N. MIELCAREK, France)
"Characterization of B. pertussis Autophagic Response in a Model of Alveolar Macrophages"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Bibiana Petri da Silveira (Texas A&M University, United States)
"Recombinant Virulence-Associated Protein A Restores Replication of Avirulent Rhodococcus equi in Macrophages Independently of Surface Receptors TLR2, CR3, and Fc?RIII"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Yingxue Wang (University of East Anglia, United Kingdom)
"LC3-Associated Phagocytosis in Airway Epithelial Cells Protects Against Influenza A Virus-Induced Lethal Infection"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Pei Min Thong (National University of Singapore, Singapore)
"Increased Neutrophil Oxidative Stress, TNFR and RAGE Contribute to the Hyperinflammatory Immunopathology of Diabetes-Tuberculosis: Data from a Cellular Model and Human Cohort"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Katelyn Sheneman (University of Louisville, United States)
"Yersinia pestis Actively Influences Extracellular Vesicle Production by Human Neutrophils"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Sarah Monard (Institut de Pharmacologie et de Biologie Structurale, France)
"Uncovering the Dynamics of Pulmonary Siglec-1+ Macrophages in Tuberculosis"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Mechanisms of Phagocytosis, Micropinocytosis and Cell Migration
Discussion Leader: Julian Hattler (Eastern Virginia Medical School , United States)
9:00 am - 9:10 am
Joyce Chiu (Centenary Institute, University of Sydney, Australia)
"Mechano-Redox Control of Mac-1 De-Adhesion from ICAM-1 by Protein Disulfide Isomerase Promotes Directional Movement of Neutrophils Under Flow"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
Matheus Silverio De Mattos (KU Leuven, Belgium)
"Natural Antibodies as “Eat-Me” Signals for Phagocytosis of Necrotic Cell Debris at Sites of Tissue Injury"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
Thomas Pelgrim (UMC Utrecht, Netherlands, The Netherlands)
"Eosinophils and Neutrophils Exhibit Similar Chemotaxis Characteristics Despite a Clear Difference in Nuclear Morphology"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Kevin Schneider (University of Virginia, United States)
"Examination of the Macrophage Responses to Reduced Efferocytosis: Does How You Eat Matter?"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
Clare Muir (University of Sheffield, United Kingdom)
"Deciding What to Eat; When Neutrophils Have a Taster but not a Second Course"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Yang Xu (University of Michigan, United States)
"Keratinocyte- and Keratin 17-Dependent Neutrophil Recruitment in Skin Inflammation"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
Benjamin Winer (Memorial Sloan Kettering Cancer Center and University of California San Francisco, United States)
"Excess Plasma Membrane Mechanically Regulates Functional Decision-Making in Myeloid CellS"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
Alexander Settle (Memorial Sloan Kettering Cancer Center, United States)
"Investigating Phagocytic Mechanosensing Using Engineered Hydrogel Particles"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Mentorship Panel: Toolkit for a Successful Career in Academia
Discussion Leader: Savini Thrikawala (Clemson University, United States)
1:30 pm - 2:10 pm
Panel Discussion
Toolkit for a Successful Career in Academia
Johnathan Canton (University of Calgary, Canada)
Juhi Bagaitkar (Nationwide Children's Hospital and The Ohio State University, United States)
Rosemary Bayless (North Carolina State University College of Veterinary Medicine, United States)
2:10 pm - 2:30 pm
General Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes
