Mechanistic Understanding of G-Protein and Kinase Signaling Leading to Development of Novel Therapeutics

The conference is dedicated to understanding the intracellular processes initiated upon receptor activation in cells, tissues, and organisms with a focus on integration of G protein and protein kinase signaling pathways. These pathways dramatically impact cell physiology and are central to coordinating intercellular communication throughout the body. Manipulation of these pathways is central to current and future therapeutic approaches for treatment of a broad range of pathologies including cardiovascular disease, pain management, cancer, neurological disorders and more. The major focus of this meeting is to showcase research that highlights recent advances in understanding the basic mechanistic functions of G protein and kinase signaling pathways and how these signaling systems are integrated at organismal, cellular, and subcellular levels. Understanding mechanism is central to development of novel therapeutics and G protein signaling and kinases are major therapeutic targets. Historically, this conference has brought together leaders in their fields with early career scientists to stimulate the next generation of scientist to pursue research that leads to continued advances in this area. Our goal is to continue this strong tradition.