SATURDAY |
1:00 pm - 5:00 pm | Arrival and Check-in |
3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:45 pm - 4:30 pm | Keynote Session |
| Discussion Leader: TBA |
3:45 pm - 4:15 pm | Forest White (Massachusetts Institute of Technology, USA)
"Quantitative Analysis of the Effect of Oncogenic Mutations on Signaling Networks"
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4:15 pm - 4:30 pm | Discussion |
4:30 pm - 6:00 pm | Poster Session I |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Physiology of Signal Transduction |
| Discussion Leader: Jessie English (DFCI, Belfer Institute, HMS, USA) |
7:30 pm - 7:50 pm | Collin Higgins (The University of Iowa, USA)
"Biophysical Interrogation of Regulator of G Protein Signaling (RGS) Structure and Dynamics Diversity with Chemical Probes"
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7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Jeremiah Keyes (Wake Forest University, USA)
"Modulation of ERK Activity by Reversible Cysteine Modification"
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8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Juliana Antonipillai (Victoria University, Austrailia)
"The Role of LIM Kinase 2 (LIMK2) in the Regulation of Platelet Function"
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8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Shana Hardy (Purdue University, USA)
"Investigating a New Role of Syk in Processing Bodies and mRNA Metabolism"
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9:20 pm - 9:30 pm | Discussion |
SUNDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Nontraditional Systems of G Protein Signaling |
| Discussion Leader: Xuewu Zhang (UT Southwestern Medical Center, USA) |
9:00 am - 9:20 am | Daisuke Urano (The University of North Carolina at Chapel Hill, USA)
"The Ancestral State of G Protein Pathways: Studies in Plants, Trichomononas and Capsaspora" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Ganesh Kadamur (UT Southwestern Medical Center, USA)
"Insights into Gβγ Regulation of Phospholipase Cβ"
|
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Mario Rossi (National Institutes of Health, USA)
"Hepatocyte-Specific Activation or Disruption of Gi Signaling in Mice Causes Pronounced Changes in Glucose Homeostasis"
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10:20 am - 10:30 am | Discussion |
10:30 am - 10:50 am | Cameron Brand (UT Health Science Center, USA)
"Scaffolding Versus Regulation of Adenylyl Cyclase Isoforms by Gβγ"
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10:50 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:30 pm | Nuts and Bolts: Emerging Technologies |
| Discussion Leader: Michael Kalwat (UT Southwestern Medical Center, USA) |
1:30 pm - 1:50 pm | Joshua Lubner (University of Connecticut, USA)
"ProPeL: Using E. coli to Generate High Resolution Models of Protein Kinase Specificity"
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1:50 pm - 2:00 pm | Discussion |
2:00 pm - 2:20 pm | Kristoff Homan (University of Michigan, USA)
"G Protein-Coupled Receptor Kinase Selective Small Molecule Inhibitors"
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2:20 pm - 2:30 pm | Discussion |
2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
3:00 pm | Seminar Concludes |