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Phosphorylation and G-Protein Mediated Signaling Networks (GRS)

Gordon Research Seminar

Discoveries in G Protein Signaling Biochemistry and Therapeutic Potential

June 2 - 3, 2018

Chair Taylor J. Moon

Conference Description

The Gordon Research Seminar on Phosphorylation and G-Protein Mediated Signaling Networks is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

An important component of this seminar is discussion, both formal question sessions following presentations, as well as informal discussions. The meeting is designed to present the most recent information about GPCRs, kinases, and phosphatases, and highlight important advances in our understanding of GPCR-mediated signal transduction. This GRS will focus on current therapeutic strategies targeting G protein signaling and will examine future drug targets and mechanisms being discovered.

Related Meeting

This GRS will be held in conjunction with the "Phosphorylation and G-Protein Mediated Signaling Networks" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
2:00 pm - 5:00 pm	Arrival and Check-in
3:30 pm - 3:45 pm	Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm	Keynote Session: Regulation of Exocytosis by Inhibitory GPCRs and Gbg Subunits Discussion Leaders: Anibal Garza Carbajal (University of Texas Health Science Center at Houston, USA) and Dmitry Akhmedov (University of Texas Health Science Center at Houston, USA)
3:45 pm - 4:15 pm	Heidi Hamm (Vanderbilt University School of Medicine, USA) "Regulation of Exocytosis by Inhibitory GPCRs and Gbg Subunits"
4:15 pm - 4:30 pm	Discussion
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Signaling Network Regulation in Disease Discussion Leaders: Ankita Jaykumar (University of Texas Southwestern Medical Center, USA) and Taylor Moon (University of Rochester, USA)
7:30 pm - 7:50 pm	Anibal Garza Carbajal (University of Texas Health Science Center at Houston, USA) "Mechanisms Inducing Opioid Resistance After Spinal Cord Injury"
7:50 pm - 8:00 pm	Discussion
8:00 pm - 8:20 pm	Lisa Lippert (University of Minnesota, USA) "Allosteric Effects of ATP-Competitive Inhibitors on Regulatory Interactions in Multi-Domain Kinases"
8:20 pm - 8:30 pm	Discussion
8:30 pm - 8:50 pm	Christina Lucato (Monash University, Australia) "An Integrated Structural Characterization of P-Rex1 Activity in Cancer Cell Signaling"
8:50 pm - 9:00 pm	Discussion
9:00 pm - 9:20 pm	Tanya Baldwin (McGovern Medical School, University of Texas Health Science Center at Houston, USA) "Insights into the Regulatory Properties of Human Adenylyl Cyclase Type 9"
9:20 pm - 9:30 pm	Discussion
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Developments in Cell Signaling Networks Discussion Leader: Christina Lucato (Monash University, Australia)
9:00 am - 9:20 am	Daniel DeHelian (University of Pennsylvania, USA) "The Role of RGS10 in Modulating Platelet GPCR Signaling Networks"
9:20 am - 9:30 am	Discussion
9:30 am - 9:50 am	Nicole Tensmeyer (Brigham Young University, USA) "Chaperone Mediated Assembly of mTOR Complexes"
9:50 am - 10:00 am	Discussion
10:00 am - 10:20 am	Ankita Jaykumar (University of Texas Southwestern Medical Center, USA) "Biological Cross-Talk Between WNK1 and TGF-Beta Signaling Pathway"
10:20 am - 10:30 am	Discussion
10:30 am - 10:50 am	Venkata Siddartha Yerramilli (Worcester Polytechnic Institute, USA) "Characterization of IQGAP1 Binding to Phosphoinositides and PIP Kinases"
10:50 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Mentorship Component: Life Beyond a PhD Discussion Leaders: Daniel DeHelian (University of Pennsylvania, USA) and Lisa Lippert (University of Minnesota, USA)
1:30 pm - 1:40 pm	Yingrong Xu (Pfizer, USA) "Phosphobarcodes for Biased Signaling"
1:40 pm - 1:45 pm	Discussion
1:45 pm - 1:55 pm	Heidi Hamm (Vanderbilt University School of Medicine, USA) "Jobs in Academia"
1:55 pm - 2:00 pm	Discussion
2:00 pm - 2:30 pm	Panel Discussion Beyond a PhD Heidi Hamm (Vanderbilt University School of Medicine, USA) Yingrong Xu (Pfizer, USA)
2:30 pm - 3:00 pm	Evaluation Period Fill in GRS Evaluation Forms
3:00 pm	Seminar Concludes

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Conference History Phosphorylation and G-Protein Mediated Signaling Networks

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