Phosphate Balance in Health and Disease

Phosphate is an essential mineral that is required for cell and organ function. Altered phosphate balance contributes to a variety of diseases. Maintaining phosphate balance involves complex interaction between several organs, and endocrine and metabolic regulators. The Gordon Research Conference (GRC) and Gordon Research Seminar (GRS) on Physiology, Biology and Pathology of Phosphate focus on the latest advances in this field, integrating basic science and clinical relevance. The 2025 GRC is designed to attract a vibrant community of junior and established basic scientists, clinical researchers, and physicians, from across the world to facilitate opportunities for networking between diverse disciplines. We will discuss cutting-edge science and innovations on multiple exciting aspects of phosphate research. Among these, the conference program includes plenary sessions dedicated to the endocrine and local regulators of phosphate metabolism, the crosstalk between phosphate and iron metabolism, the importance of phosphate balance in skeletal health, and the impact of dietary phosphate on phosphate balance. We will discuss how these intersect in diseases associated with phosphate excess and deficiency, novel mechanisms of vascular and ectopic calcifications, and ongoing clinical trials and novel therapies that address phosphate disorders. Additionally, to gain a fresh perspective on the mechanisms of phosphate metabolism, we will learn from interesting studies performed in various different species. Finally, the program features a Power Hour session that addresses networking without borders, multiple poster sessions, and downtime for social activities and networking.

We welcome abstract submissions from all participants. Best ranking abstracts submitted prior to December 8th, 2024 will be integrated in plenary sessions as short oral presentations.