Saturday
1:30 pm - 4:30 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm
Keynote Session: Discovery and Characterization of Novel Plant Metabolism
Discussion Leader: Thu Thuy Dang (The University of British Columbia, Canada)
3:15 pm - 3:50 pm
Jing-Ke Weng (Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, USA)
"Vision for a Sustainable Biocatalyst-Based Pharmaceutical Industry"
3:50 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Engineering Production of Valuable Plant-Derived Products
Discussion Leaders: Judith Booth (University of British Columbia, Canada) and Michelle McKee (Worcester Polytechnic Institute, USA)
5:30 pm - 5:45 pm
Camille Chalvin (University of Paris-Saclay, France)
"Isotope Labeling and Mass Spectrometry Imaging to Understand Sclareol Production in Clary Sage"
5:45 pm - 5:50 pm
Discussion
5:50 pm - 6:05 pm
Thies Gülck (University of Copenhagen, Denmark)
"The Biosynthesis of Cannabinoids in Tobacco and Yeast"
6:05 pm - 6:10 pm
Discussion
6:10 pm - 6:25 pm
Sandra Irmisch (Michael Smith Laboratories, University of British Columbia, Canada)
"A Novel Anti-Diabetic Compound from Plants: Biosynthesis, Gene Discovery and Metabolic Engineering of Montbretin A"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
Scott Farrow (John Innes Centre, United Kingdom)
"A Cytochrome P450 and O-Methyltransferase Catalyze the Final Steps in the Biosynthesis of the Anti-Addictive Alkaloid Ibogaine from Tabernanthe iboga "
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:05 pm
Quentin Dudley (Earlham Institute / John Innes Centre, United Kingdom)
"Improving Nicotiana benthamiana as a Bioproduction System for Proteins and Small Molecules"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
Maite Colinas (VIB-UGent Center of Plant Systems Biology, Belgium)
"Controlling Pathway Branch Choice by Engineering the Transcriptional Regulation of Specialized Metabolism in the Medicinal Plant Catharanthus roseus "
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Harnessing Plant Metabolism for Enhanced Agriculture / Developing Tools to Elucidate and Co-Opt Plant Metabolism
Discussion Leaders: Fabiola Muro-Villanueva (Purdue University, USA) and Davide Mancinotti (University of Copenhagen, Denmark)
9:00 am - 9:15 am
Ronan Broad (The University of Melbourne, Australia)
"Metabolic Engineering of Rice to Increase Ascorbate Biosynthesis"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Hester Sheehan (University of Cambridge, United Kingdom)
"Tryosine-Enriched Metabolism and the Evolution of a Novel Tyrosine-Derived Metabolite"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Eric Holmes (Stanford University, USA)
"Engineering of Metabolite-Based Systemic Disease Resistance in Crop Plants"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Jeffrey Simpson (Purdue University, USA)
"Metabolic Source Isotopic Pair Labeling and GWAS Are Complementary Tools for the Elucidation of Gene Function and Metabolite Identity in Plants"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Andrew Mitchell (Whitehead Institute for Biomedical Research, MIT, USA)
"Systematic Engineering of Plant 2-Oxoglutarate/Fe(II)-Dependent Dioxygenases for Novel Small-Molecule Chlorination and Azidation Chemistry"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Guy Polturak (John Innes Centre, United Kingdom)
"Genomics-Driven Discovery of Novel Triterpene Biosynthetic Pathways in the Grasses"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Careers Within and Without Academia
Discussion Leaders: Lira Palmer (John Innes Centre, United Kingdom) and Jie Li (John Innes Centre, United Kingdom)
1:30 pm - 2:30 pm
Panel Discussion
Exploring Professional Opportunities in Academia, Publishing and Industry
Susanne Brink (Trends in Plant Science, Cell Press, United Kingdom)
Angela Hendrickson Culler (Bayer CropScience, USA)
Sibongile Mafu (University of Massachusetts Amherst, USA)
Surinder Singh (Agriculture and Food, CSIRO, Australia)
Jing-Ke Weng (Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes