| Sunday July 22 |
| I. Chromosome and Nuclear Structure 1 |
| Chair: Gary Karpen |
| 7:15 PM | WELCOME |
| 7:30 PM | Joanna Bridger, Brunel University, UK
"Interphase Chromosome Positioning - What's Involved?" |
| 8 PM | John Marko, University of Illinois, Chicago
``Micromechanical Experiments on Mitotic Chromosomes" |
| 8:30 PM | Nancy Kleckner, Harvard U, Cambridge
"A Physico-mechanical view: chromosome breathing with resultant imposition and relief of stress governs chromosome activity" |
| 9 PM | Patrick Higgins, U of Alabama, Birmingham
"DNA Dynamics and Domain Structure in Bacterial Chromosomes" |
| 9:30 PM | BAR |
| Monday July 23 |
| II. Chromosome and Nuclear Structure 2 |
| Chair: Titia de Lange |
| 9 AM | Alexei Tulin, Carnegie Inst of Washington, Baltimore
"Developmental Functions of ADP-ribosylation" |
| 9:30 AM | Lenny Guarente, MIT, Cambridge
"Sir2 regulates aging in yeast and worms" |
| 10 AM | John Moran, U of Michigan Medical School, Ann Arbor
"Studies of a Human Transposon" |
| 10:30 AM | BREAK & PHOTO |
| III. Telomeres |
| Chair: Abby Dernburg |
| 11 AM | Titia de Lange, Rockefeller U, New York
"Protection and Maintenance of Human Telomeres" |
| 11:30 AM | Julia Cooper, U of Colorado Health Science Center, Denver
"Telomeres and the Control of Cell Division" |
| 12 PM | Virginia Zakian, Princeton U
"Telomere Maintenance in Yeast" |
| 12:30 PM | LUNCH |
| 4:30 PM | POSTER SESSION |
| 6 PM | DINNER |
| IV. DNA and Chromatin Replication |
| Chair: Allan Spradling |
| 7:30 PM | Saleem Khan, U of Pittsburgh School of Medicine
"DNA-protein Interactions during the Initiation and termination of Plasmid Rolling Circle Replication" |
| 8 PM | Elliot Crooke, Georgetown U Med Center, Washington DC
"DnaA Protein-Membrane Interactions in the Replication of the E. coli Chromosome." |
| 8:30 PM | Jorge Schvartzman, Centro de Investigaciones Biologicas, Madrid, Spain
"In Partially Replicated Plasmids Positive Supercoiling Leads to Replication Fork Reversal" |
| 9 PM | K. Raghuraman, U of Washington, Seattle
"The Dynamics of Chromosome Replication in Yeast" |
| Tuesday July 24 |
| V. Condensation and Cohesion |
| Chair: Rebecca Heald |
| 9 AM | Nancy Trun, Duquesne University, Pittsburgh
"Structure/function analysis of CspE, a small, bi-functional nucleic acid binding protein involved in chromosome folding" |
| 9:30 AM | Tatsuya Hirano, Cold Spring Harbor Labs
"Mechanisms of chromosome condensation from bacteria to humans" |
| 10 AM | Nick Cozzarelli, U of California, Berkeley
"Mechanisms of chromosome condensation from bacteria to humans" |
| 10:30 AM | BREAK |
| 11 AM | Hironori Funabiki, Harvard U, Cambridge
"Mining chromosomes in Xenopus egg extracts" |
| 11:30 AM | Kirsten Hagstrom, U of California, Berkeley
"Mitotic Chromosome Condensation and Segregation by a Conserved Protein Complex" |
| 12 PM | Terry Orr-Weaver, Whitehead Institute/MIT, Cambridge
"Regulation of DNA replication and chromosome segregation in Drosophila" |
| 12:30 PM | LUNCH |
| 4:30 PM | POSTER SESSION |
| 6 PM | DINNER |
| VI. Plasmid and Chromosome Segregation 1 |
| Chair: Saleem Khan |
| 7:30 PM | Stuart Austin, NCI-FCRDC, Frederick
"Segregation of the P1 plasmid by time-lapse photomicroscopy" |
| 8 PM | Alan Grossman, MIT, Cambridge
"DNA replication and chromosome partitioning in bacteria" |
| 8:30 PM | Barbara Funnell, U of Toronto, Toronto, Canada
"The action of ParA and ParB in P1 plasmid partition" |
| 9 PM | David Lane, CNRS, Toulouse, France
"The Role of SopA ATPase in Autoregulation
and in Partition of Plasmid F" |
| 9:30 PM | BAR |
| Wednesday July 25 |
| VII. Plasmid and Chromosome Segregation 2 |
| Chair: Barbara Funnell |
| 9 AM | Joe Pogliano, U of California, San Diego
"Segregation of multicopy plasmids in bacteria" |
| 9:30 AM | Soundarapandian Velmuragan, U of Texas, Austin
"Dynamics of 2 Micron Plasmid Segregation in Yeast by Time-Lapse Fluorescence Microscopy" |
| 10 AM | Ken Marians, Mem. Sloan-Kettering Cancer Center, NY
"An Interaction between Topoisomerase IV and the Replication Machinery
that Affects Chromosome Segregation in vivo" |
| 10:30 AM | BREAK |
| VIII. Centromeres and Kinetochores 1 |
| Chair: Kevin Sullivan |
| 11 AM | Paul Kaufman, Lawrence Berkeley Natl Labs, UC Berkeley
"Function of Chromatin Assembly Proteins at the Yeast Centromere." |
| 11:30 AM | Ines Pinto, U of Arkansas, Fayetteville
"The Role of Centromeric Chromatin during Chromosome Segregation in S. cerevisiae" |
| 12 PM | Pam Meluh, Mem. Sloan-Kettering Cancer Center, NY
"The Smt3p/SUMO-1 pathway impacts genomic stability in yeast" |
| 12:30 PM | LUNCH |
| 4:30 PM | POSTER SESSION |
| 6 PM | DINNER |
| IX. Centromeres and Kinetochores 2 |
| Chair: Don Cleveland |
| 7:30 PM | Janet Partridge, MRC Human Genetics Unit, Edinburgh, UK
"A Cis-acting Element from Fission Yeast Centromeres Mediates Histone H3 Methylation and Recruitment of Silencing Factors at Ectopic Sites" |
| 8 PM | Beth Sullivan, The Salk Institute, La Jolla
"FISHing and ChIPing at Drosophila centromeres" |
| 8:30 PM | Kevin Sullivan, Scripps Research Institute, La Jolla
"Assembly and Post-translational Modification of Kinetochore Chromatin:
A Tale of Two Templates" |
| 9 PM | Daphne Preuss, U of Chicago
"The Arabidopsis Centromeres: From DNA Sequence to Function" |
| 9:30 PM | BAR |
| Thursday July 26 |
| X. Centromeres and Kinetochores 3 |
| Chair: Terry Orr-Weaver |
| 9 AM | Peter Warburton, Mount Sinai School of Medicine, New York
"Expression of CENP-B/CENP-A fusion proteins in mammalian cells containing ectopic alpha satellite DNA" |
| 9:30 AM | Don Cleveland, Ludwig Institute, U of California, San Diego
"Centromeres, CENP-E, Mps1, and the Mitotic Checkpoint" |
| 10 AM | Rebecca Heald, U of California, Berkeley
"Centromeres: Who Needs Em? The Role of Non-centromeric Chromatin in Spindle Assembly" |
| 10:30 AM | BREAK |
| XI. Meiosis 1 |
| Chair: Pat Hunt |
| 11 AM | Sean Burgess, U of California, Davis
"Probing the three-dimensional space of the meiotic nucleus in yeast using site-specific recombination" |
| 11:30 AM | Kaiming Sun, Brandeis University
"Exploring Chromosome Architecture by Studying Recombination" |
| 12 PM | Vince Guacci, Fox Chase Cancer Center, Philadelphia
"The Budding Yeast PDS5 Gene Encodes a Chromosomal Protein Required for Chromatid Cohesion and Condensation during Meiosis" |
| 12:30 PM | LUNCH |
| 4:30 PM | POSTER SESSION |
| 6 PM | DINNER |
| XII. Meiosis 2 |
| Chair: Julia Cooper |
| 7:30 PM | Scott Hawley, U of California, Davis
"Chromosome Pairing and Segregation in Drosophila females" |
| 8 PM | Mónica Colaiácovo, Stanford U, Palo Alto
"Assembly and Function of the Synaptonemal Complex in C. elegans Meiosis" |
| 8:30 PM | Abby Dernburg, Lawrence Berkeley Nat. Labs, UC Berkeley
"Sex and the Single Pairing Center" |
| 9 PM | Pat Hunt, Case Western Reserve U, Cleveland
"Meiotic chromosome segregation in the human female" |
| 9:30 PM | BAR |
