SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Chromatin and Chromosome Organization |
| Discussion leader: Patrick Higgins (University of Alabama, Birmingham) |
| John Marko (University Illinois, Chicago) Micromanipulation study of chromatin and chromosomes |
| Nancy Craig (Johns Hopkins University School of Medicine, Baltimore) Using Transposons to Study Chromosome Organization |
| Lori L Wallrath (University of Iowa, Iowa City) Heterochromatin Protein 1: A structural component for chromatin compaction and regulated gene expression |
| Shiv Grewal (NIH, Bethesda) Linking higher-order chromatin assembly to RNAi |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Replication |
| Discussion leader: Barbara Funnell (University of Toronto, Canada) |
| Elliott Crooke (Georgetown University Medical Center, Washington, DC) Temporally and Spatially Controlled Initiation of E. coli Chromosomal Replication |
| James Berger (University of California, Berkeley) Building a structural framework for DNA replication initiation |
| Michael O'Donnell (Rockefeller University, New York) Intelligence Underling a Processivity Switch in the E. coli Replication Machine |
10:30 am - 11:00 am | Coffee Break |
| Discussion leader: Elliott Crooke (Georgetown Univ Medical Center, Washington, DC) |
| Kenneth Kreuzer (Duke University, Durham) Stopping and re-starting replication forks in bacteriophage T4 |
| Saleem Khan (University of Pittsburgh School of Medicine) Role of the PcrA helicase in DNA transactions |
| Dhruba Chattoraj (NIH, Bethesda) Dampening of noise in plasmid copy number by autoregulation |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Chromosome Domains |
| Discussion leader: Lori L. Wallrath (University of Iowa, Iowa City) |
| Patrick Higgins (University of Alabama, Birmingham) Chromosome domains: stochastic and process-specific boundary formation |
| Sigal Ben-Yehuda (Harvard University, Cambridge) RacA, a Bacterial Protein That Anchors Chromosomes to the Cell Poles |
| Jeannie Lee (Massachusetts General Hospital, Harvard University, Boston) Epigenetic regulation of X-chromosome inactivation |
| Raymond Chan (University of California, Berkeley)
Participation of the C. elegans clock gene paralog TIM-1 in chromosome cohesion reveals new roles for cohesin and condensin in meiosis
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TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Centromeres and Kinetochores |
| Discussion leader: Angelika Amon (MIT, Cambridge) |
| Daphne Preuss (University of Chicago) Centromere structure and function in Arabidopsis and its relatives |
| Jason Swedlow (University of Dundee, United Kingdom) Aurora B protein kinase regulates the centromere targeting and microtubule depolymerising activity of MCAK |
| Barbara Funnell (University Toronto, Canada) The interactions of ParA, ParB, and ATP during partition of P1 plasmids in E. coli |
10:30 am - 11:00 am | Coffee Break |
| Discussion leader: David Sherratt (Oxford University, United Kingdom) |
| Gary Karpen (Lawrence Berkeley National Labs, UC Berkeley) Centromeric chromatin and kinetochore function |
| Alicia Alonso (Mount Sinai School of Medicine, New York) Identification of CENP-A binding domains at human neo-centromeres |
| Kenn Gerdes (University of Southern Denmark) Prokaryotic analogue of the eukaryotic spindle: Plasmid DNA segregation by an F-actin-like filament |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Condensation and Cohesion |
| Discussion leader: Nick Cozzarelli (University of California, Berkeley) |
| Carlos Bustamante (University of California, Berkeley) Single molecule measurements of DNA condensation |
| Tatsuya Hirano (Cold Spring Harbor Laboratory) The action of condensin in vivo and in vitro |
| Sota Hiraga (Kyoto University, Japan) Chromosome dynamics in E. coli |
| Brigitte Lavoie (University of Toronto, Canada) In vivo requirements for chromosome condensation reveal two cell cycle regulated pathways for mitotic chromosome folding |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Chromosome Segregation |
| Discussion leader: Nancy Craig (Johns Hopkins Univ School of Medicine, Baltimore) |
| Angelika Amon (MIT, Cambridge) The role of Cdc14 in controlling chromosome segregation |
| Stuart Austin (NCI, Frederick) The dynamics of Eschericia coli chromosome segregation |
| Kenneth Marians (Memorial Sloan Kettering Cancer Center, New York) Topoisomerase IV and Chromosome Segregation in E. coli |
10:30 am - 11:00 am | Coffee Break |
| Discussion leader: Stuart Austin (NCI, Frederick) |
| David Sherratt (Oxford University, United Kingdom) Action of FtsK in bacterial chromosome segregation |
| Nick Cozzarelli (University of California, Berkeley) Enzymes involved in the segregation of completed daughter chromosomes |
| Makkuni (Jay) Jayaram (University of Texas, Austin) The Coupling of plasmid and chromosome segregation in yeast is mediated through the mitotic spindle and the cohesin complex |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm | Business Meeting |
7:30 pm - 9:30 pm | Ends |
| Discussion leader: Jim Haber (Brandeis University, Waltham) |
| Ginger Zakian (Princeton University) Regulation of telomerase in yeast |
| George Chaconas (University of Calgary, Canada) Telomere resolution and DNA replication in Borrelia burgdorferi, the Lyme disease spirochete |
| Anne Stellwagen (Fred Hutchinson Cancer Research Center, Seattle) Recruiting Telomerase to Different Kinds of DNA Ends: A Role For Ku |
| Hironori Funabiki (Rockefeller University, New York) Identification and characterization of chromosome binding proteins involved in chromosome maintenance |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Genome Plasticity |
| Discussion leader: Ginger Zakian (Princeton University) |
| Jeff F. Miller (University of California, Los Angeles) Diversity-generating Retroelements |
| John Moran (University of Michigan Medical School, Ann Arbor) Studies of a Human Retrotransposon |
| James Haber (Brandeis University, Waltham) Constraints on chromosome movement during recombination |
10:30 am - 11:00 am | Coffee Break |
| Discussion leader: Saleem Khan (University of Pittsburgh School of Medicine) |
| Matt Waldor (Tufts University School of Medicine, Boston) Mechanisms of gene exchange in Vibrio cholerae |
| David Dubnau (Public Health Research Institute, Newark) Mechanisms and regulation of genetic transformation in bacteria |
| Matt Thayer (Oregon Health Sciences University, Portland) Chromosome rearrangements and delayed mitotic chromosome condensation |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Pairing and Meoisis |
| Discussion leader: Gary Karpen (Lawrence Berkeley National Labs, UC Berkeley) |
| Abby Dernburg (Lawrence Berkeley National Labs, UC Berkeley) Coordinating Pairing and Synapsis during Meiosis |
| Scott Hawley (Stowers Institute, Kansas City, MO) The analysis of a simple meiotic system in Drosophila melanogaster females |
| Sharon Bickel (Dartmouth College, Hanover) Sister-chromatid cohesion and chromosome segregation during meiosis in Drosophila |
| Kentaro Nabeshima (Stanford University) Meiotic chromosome morphogenesis and function in C. elegans |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |