| SATURDAY |
| 1:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | KEYNOTE LECTURE |
| 3:45 pm - 4:15 pm | André S. Bachmann (University of Hawaii)
"Polyamine research: from plants to cancer" |
| 4:15 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | BIOCHEMISTRY AND ENZYMATIC PATHWAYS OF POLYAMINES |
| Discussion Leader: Eugene Gerner (University of Arizona) |
| Student Discussion Leader: Tânia Silva (University of Coimbra) |
| 7:30 pm - 7:45 pm | Takeshi Uemura (University of Arizona, USA)
"Caveolin and antizyme dependent regulation of protein sorting" |
| 7:45 pm - 7:50 pm | Discussion |
| 7:50 pm - 8:05 pm | Manuela Cervelli (University of "Roma Tre", Rome, Italy)
"Changing substrate specificity: turning spermine oxidase to acetylpolyamine oxidase" |
| 8:05 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:25 pm | Mizuho Nakamura (Chiba Institute of Science, Japan)
"Different mechanisms of the resistance to acrolein toxicity of the acrolein resistant mutants" |
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:45 pm | Sini Pirnes-Karhu (University of Eastern Finland)
"Effect of Spermidine/Spermine-N1-Acetyltransferase (SSAT) on Hematopoiesis" |
| 8:45 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:05 pm | Naoki Nemoto (Graduate School of Science and Technology, Kyoto, Japan)
"Regulation of putrescine utilization pathway by a transcriptional factor PuuR in Escherichia coli K-12" |
| 9:05 pm - 9:10 pm | Discussion |
| 9:10 pm - 9:25 pm | Aaron Muth (University of Central Florida, USA)
"Optimized Polyamine Transport Ligands for Cell Selective Drug Delivery" |
| 9:25 pm - 9:30 pm | Discussion |
| 9:30 pm | Reception |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | POLYAMINE RESEARCH IN HUMAN HEALTH AND DISEASE |
| Discussion Leader: Heather Wallace (University of Aberdeen, Scotland) |
| Student Discussion Leader: Theresa Carr (Pennsylvania State University) |
| 9:00 am - 9:15 am | Edwin Paz (University of Arizona, USA)
"Inhibition of Polyamine Synthesis in Colon Cancer Cells Alters Expression of microRNAs and Cancer-Associated Genes" |
| 9:15 am - 9:20 am | Discussion |
| 9:20 am - 9:35 am | Olga Smirnova (Russian Academy of Sciences)
"Hepatitis C virus activates antioxidant defense system and perturbs polyamine metabolism via Nrf2 pathway" |
| 9:35 am - 9:45 am | Discussion |
| 9:45 am - 10:00 am | Nahir Velez (UT Southwestern Medical Center, USA)
"Targeting Trypanosoma brucei S-adenosylmethione decarboxylase in drug discovery" |
| 10:00 am - 10:10 am | Discussion |
| 10:10 am - 10:25 am | Tamara Olenyik (Oregon Health and Science University, USA)
"The Role of Polyamine Biosynthesis in Leishmania donovani Infectivity" |
| 10:25 am - 10:35 am | Discussion |
| 10:35 am - 10:50 am | Bianca Verlinden (University of Pretoria, South Africa)
"Exploring the antimalarial potential of (bis)urea and (bis)thiourea-alkylated polyamine analogues" |
| 10:50 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:45 pm | MICE, MEN, AND FRUIT |
| Discussion Leader: Andrew Goodwin (Johns Hopkins University) |
| Student Discussion leader: Valentina Battaglia (University of Rome "La Sapienza") |
| 1:30 pm - 1:45 pm | Carlos López-García (University of Murcia School of Medicine, Spain)
"In vivo approach to the physiological roles of antizyme inhibitor-2" |
| 1:45 pm - 1:55 pm | Discussion |
| 1:55 pm - 2:10 pm | Raheel Anwar (Purdue University, USA)
"Polyamine regulated alteration in fruit architecture" |
| 2:10 pm - 2:20 pm | Discussion |
| 2:20 pm - 2:35 pm | Elif Damla Arisan (Istanbul Kultur University, Turkey)
"Roscovitine induced apoptosis and activated polyamine catabolic pathway in LNCap, DU145 and PC3 prostate cancer cell lines" |
| 2:35 pm - 2:45 pm | Discussion |
| 2:45 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
| 3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |
