Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Coupling of Transcription and Splicing
3:45 pm - 3:55 pm
"Exploring the Nascent Transcriptome with Direct RNA Nanopore Sequencing"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 4:10 pm
"Splicing-Dependent Regulation of Transcription Start Sites"
4:10 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
"Genome-Wide Determination of Splicing Kinetics and Transcript Elongation Rates in Mammalian Cells"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
RNA Processing and Modifications
7:30 pm - 7:40 pm
"Most Human Introns Are Recognized via Multiple and Tissue-Specific Branchpoints"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Pseudouridine Synthases Modify Human Pre-mRNA Co-Transcriptionally and Affect Splicing"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"The Role of N6-Methyladenosine in RNA Virus Infection"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:30 pm
"Single Molecule Imaging of mRNA Behavior Reveals Heterogeneous Dynamic Interactions with Stress Granules and P-Bodies in Human Cells"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:50 pm
"NPM1 Germline and Somatic Mutations Demonstrate a Central Role for Ribosomal RNA Methylation in Hematopoiesis and Cancer"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:10 pm
"Moonlighting Function of Glycogen Synthase 1 in RNA Metabolism"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:30 pm
General Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
RNA Translation / Mentorship Component: Discussion with Academic and Industry Leaders
9:00 am - 9:10 am
"Active Ribosome Profiling with RiboLace"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
"The Energy Landscape of Ribosomal Frameshifting"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Decoupling the Impact of microRNAs on Translational Repression Versus RNA Degradation in Embryonic Stem Cells"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"RNA Structure Centric Machine Learning of Primary microRNA Biogenesis"
9:55 am - 10:00 am
Discussion
10:00 am - 11:00 am
Panel Discussion
An Informal Discussion with Academic and Industry Leaders
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
RNA Processing in Human Disease
1:30 pm - 1:45 pm
"Herpes Simplex Virus Infection Reveals Modulation of the NXF1 Retained Intron by SF3B4"
1:45 pm - 1:50 pm
Discussion
1:50 pm - 2:05 pm
"Reprogramming Splicing Events in Cancer Using New Small Molecules and an Innovative Bifunctional Oligonucleotide Technology"
2:05 pm - 2:10 pm
Discussion
2:10 pm - 2:25 pm
"Dissecting the Transcriptome of the DM1 CNS"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes