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Preclinical Form and Formulation for Drug Discovery (GRS)

Gordon Research Seminar

New Insights and Advanced Approaches in Preclinical Drug Development

June 3 - 4, 2017
Chairs Rui Fang and Yinshan Chen

Conference Description

The Gordon Research Seminar on Preclinical Form and Formulation for Drug Discovery is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The focus of this meeting is on recent progress in understanding and new strategies in preclinical drug development including conventional formulations as well as novel therapies. Discussion topics include, but are not limited to, new approaches in enhancing solubility of poorly-soluble drugs, protein stability, targeted drug delivery, and new analytical methodologies. Additionally, experts in academia and industry will share their experience and provide a general perspective on the future of pharmaceutical research.

Related Meeting

This GRS will be held in conjunction with the "Preclinical Form and Formulation for Drug Discovery" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Preclinical Form and Formulation for Drug Discovery
Discussion Leader: Narayan Variankaval (Merck Research Laboratories, USA)
3:45 pm - 4:20 pm
Nicholas Warne (Pfizer, USA)
"Biotechnology Dosage Form Development for the Rapidly Evolving Healthcare Environment"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Parenteral Formulations: Characterization and Stability
Discussion Leaders: Adora Padilla (GSK Vaccines, USA) and Adrian Defante (National Institute of Standards and Technology, USA)
7:30 pm - 7:50 pm
Ashley Lay (University of Kentucky, USA)
"Solid-State NMR Spectroscopy: A Versatile Tool for Characterizing Lyophilized Protein Formulations"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Carly Chisholm (University of Colorado Boulder, USA)
"Stability of Therapeutic Protein Formulations in Novel Cyclic Olefin Polymer Vials and Syringes Containing Silica-Coated Surfaces"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Shreya Kulkarni (University of Connecticut, USA)
"Why Does Crystallization of Mannitol Lower the Reconstitution Times of Freeze-Dried Highly Concentrated Protein Formulations?"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Rikhav Gala (Mercer University, USA)
"Formulation and Preclinical Evaluation of a Novel Buccal and Transdermal Measles Vaccine"
9:20 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Oral Dosage Forms: Drug Delivery and Formulation
Discussion Leaders: Sachin Lohani (Janssen Pharmaceuticals, USA) and Alpana Thorat (Purdue University, USA)
9:00 am - 9:20 am
Peng Yu (The University of Iowa, USA)
"Thermodynamic Understanding of Enthalpy-Driven Adsorption Phenomena: Phenobarbital and Activated Carbons as the Model System"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Sampada Koranne (University of Minnesota, USA)
"Investigation of Spatial Heterogeneity of Salt Disproportionation in Tablets by Synchrotron X-Ray Diffractometry"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Julie Calahan (University of Kentucky, USA)
"Correlating the Effect of Physicochemical Properties of Magnesium Stearate with Indomethacin Tablet Dissolution"
10:20 am - 10:30 am
Discussion
10:30 am - 10:50 am
Bart Hens (University of Michigan, USA)
"Formulation Predictive Dissolution (fPD) for Oral Drug Products"
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Panel
Discussion Leader: Yongchao Su (Merck Research Laboratories, USA)
1:30 pm - 2:30 pm
Panel Discussion
Careers in Pharmaceutical Sciences
  • Annette Bak (AstraZeneca, Sweden)
  • Eric Munson (University of Kentucky, USA)
  • Elizabeth Topp (Purdue University, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes

Contributors

Conference Links

Conference History Preclinical Form and Formulation for Drug Discovery
Additional Fee Info

Preclinical Form and Formulation for Drug Discovery
June 22 - 27, 2025


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