Conference Description
The Protein Processing, Trafficking and Secretion GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.
Protein and lipid processing, transport and secretion is vital for the maintenance of healthy cells. Indeed, disruptions in these pathways have been linked to a broad array of diseases, including diabetes and neurodegeneration. This meeting will feature cutting-edge research on biophysical, molecular and cell biological aspects of the secretory and endocytic pathways. Invited talks will cover the processing of proteins, regulation of canonical and non-canonical secretory pathways and their integration with cellular cues, mechanisms involved in transporting cellular contents to lysosomes, as well as the relevance of these pathways to disease processes. Technological advances and challenges in the field will be discussed. The conference is organized to maximize interactions between trainees and established investigators, and in addition to daily poster sessions, will feature an assortment of social activities.
The topics, speakers, and discussion leaders for the conference sessions are displayed below. The conference chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by March 16, 2024. Please check back for updates.
Endoplasmic Reticulum Protein Import and Folding
Discussion Leaders
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Judith Frydman (Stanford University, United States)
Speakers
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Gia Voeltz (Howard Hughes Medical Institute / University of Colorado Boulder, United States)
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Pedro Carvalho (University of Oxford, United Kingdom)
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Tom Rapoport (Harvard Medical School / HHMI, United States)
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Ana Paula Arruda (UC Berkeley , United States)
Signaling, ER-To-Golgi, and Intra-Golgi Transport
Discussion Leaders
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Liz Miller (MRC Laboratory of Molecular Biology, United Kingdom)
Speakers
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Vivek Malhotra (Centre for Genomic Regulation, Spain)
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Giulia Zanetti (Birkbeck, University of London, United Kingdom)
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Benjamin Glick (University of Chicago, United States)
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Hesso Farhan (Medical University of Innsbruck, Austria)
Emerging Technologies
Discussion Leaders
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Melkam Kebede (The University of Sydney, Australia)
Speakers
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Jennifer Lippincott-Schwartz (Howard Hughes Medical Institute, United States)
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Matthias Mann (Max Planck Institute of Biochemistry, Germany)
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Ryan Potts (Amgen, United States)
TGN Processing, Sorting, and Export
Discussion Leaders
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Nabil Seidah (IRCM, Canada)
Speakers
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Christopher Burd (Yale School of Medicine, United States)
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David Gershlick (University of Cambridge, United Kingdom)
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Angelika Hausser (University of Stuttgart, Germany)
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Felix Campelo (ICFO-The Institute of Photonic Sciences, Spain)
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Rosaria Di Martino (Institute for Endocrinology and Experimental Oncology (IEOS-CNR) Napoli, Italy, Italy)
Exocytosis and Mechanisms of Unconventional Protein Secretion
Discussion Leaders
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Randy Schekman (University of California, Berkeley, United States)
Speakers
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Jayanta (Jay) Debnath (University of California, San Francisco, United States)
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Axel Brunger (Stanford University, United States)
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Li Yu (Tsinghua University, China)
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Walter Nickel (Heidelberg University Biochemistry Center, Germany)
Lysosomes and Autophagy
Discussion Leaders
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Thomas Melia (Yale University, United States)
Speakers
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Ana Maria Cuervo (Albert Einstein College of Medicine, United States)
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Susan Ferro-Novick (University of California, San Diego, United States)
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Christina Towers (The Salk Institute for Biological Studies, United States)
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Sharon Tooze (The Francis Crick Institute, United Kingdom)
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Oliver Florey (Babraham Institute, United Kingdom)
Emerging Roles of Biomolecular Condensation in Trafficking and Autophagy
Discussion Leaders
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Rohit Pappu (Washington University in St. Louis, United States)
Speakers
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James E. Rothman (Yale University, United States)
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Andreas Ernst (University of California, San Diego (UCSD), United States)
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Hong Zhang (Institute of Biophysics, Chinese Academy of Sciences, China)
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Jeanne Stachowiak (The University of Texas at Austin, United States)
Processing, Trafficking, and Secretion in Neurological Diseases
Discussion Leaders
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Anjon Audhya (University of Wisconsin-Madison, United States)
Speakers
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Suzanne Pfeffer (Stanford University School of Medicine, United States)
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Pietro De Camilli (Yale University, United States)
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Craig Blackstone (Massachusetts General Hospital and Harvard Medical School, United States)
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Shinya Yamamoto (Baylor College of Medicine, United States)
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Erika Holzbaur (University of Pennsylvania, United States)
Processing, Trafficking, and Secretion in Diabetes
Discussion Leaders
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Peter Arvan (University of Michigan Medical School, United States)
Speakers
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Alan Attie (University of Wisconsin-Madison, United States)
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Heiko Lickert (Helmholtz Zentrum München GmbH, Germany)
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Natalie Krahmer (Helmholtz Diabetes Center, Germany)
The GRC Power Hour™
Organizers
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Mike Boyce (Duke University School of Medicine, United States)
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Mary Munson (University of Massachusetts Chan Medical School, United States)
