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Protein Processing, Trafficking and Secretion (GRS)

Gordon Research Seminar

Insight into Molecular Mechanisms, Membrane Trafficking, Folding and ER Stress, Pathology and Therapeutic Applications

July 19 - 20, 2014
Chair Jeroen Declercq
Colby-Sawyer College
541 Main Street
New London, New Hampshire, United States
 Venue and Travel Information

Conference Description

The Gordon Research Seminar on Protein Processing, Trafficking & Secretion is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The focus of this meeting is recent research in cellular and molecular events in the secretory pathway, including trafficking & secretion, posttranslational processing, folding & ER stress, as well as the significance of these processes to cellular pathology and human disease. The mentorship component will focus on career development.

Related Meeting

This GRS will be held in conjunction with the "Protein Processing, Trafficking and Secretion" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

SATURDAY
1:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session
Discussion Leader: Mathilde Bonnemaison (UCHC)
3:45 pm - 4:15 pmGary Thomas (University of Pittsburgh School of Medicine)
"Leveraging Proteases: From Anthrax Activation to Cell Cycle Regulation"
4:15 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session I
6:00 pmDinner
7:30 pm - 9:30 pmProtein Processing, Trafficking and Secretion
Discussion Leader: Carolyn Fisher (Cornell University)
7:30 pm - 7:46 pmCarolyn Fisher (Cornell University)
"Investigating the Role of Cis/Trans Peptidyl-Prolyl Isomers in Signal Transduction"
7:46 pm - 7:54 pmDiscussion
7:54 pm - 8:10 pmMagdalena Schacherl (University of Cologne)
"Camelid Nanobody Driven Stabilization of an Archaeal Site-2 Protease - A Systematic Study Leading Toward the Full-Length Crystal Structure"
8:10 pm - 8:18 pmDiscussion
8:18 pm - 8:34 pmAnna Jansen (University of Copenhagen)
"The BAR Domain Protein PICK1 Controls Vesicle Number and Size in Adrenal Chromaffin Cells"
8:34 pm - 8:42 pmDiscussion
8:42 pm - 8:58 pmMonique Rogals (Cornell University)
"Elucidating the Interaction Between the Substrate Binding Domain of Human Heat Shock 70 kDa Protein (Hsp70) and the Cytosolic Tail of Amyloid Precursor Protein (APPc)"
8:58 pm - 9:06 pmDiscussion
9:06 pm - 9:22 pmBen Moore (Washington University in St. Louis)
"The Novel Transcriptional Regulation of XBP1 by HNF4a Underlies Mature-Onset Diabetes of the Youth 1 Pathology"
9:22 pm - 9:30 pmDiscussion
SUNDAY
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amProprotein Convertases in Homeostasis and Pathologies
Discussion Leader: Bas Brouwers (KU Leuven)
9:00 am - 9:16 amBas Brouwers (KU Leuven)
"Impaired Islet Function in Commonly Used Transgenic Mouse Lines Due to Human Growth Hormone Minigene Expression"
9:16 am - 9:24 amDiscussion
9:24 am - 9:40 amCamilla Gustafsen (Aarhus University, Denmark)
"Sortilin Facilitates Secretion of PCSK9 by Sorting from the Trans-Golgi Network"
9:40 am - 9:48 amDiscussion
9:48 am - 10:04 amFrederic Couture (Université de Sherbrooke)
"Novel Prostate Cancer-Specific Alternative Splicing Form of PACE4"
10:04 am - 10:12 amDiscussion
10:12 am - 10:28 amElias Blanco (University of Maryland)
"Human PC1/3 Ser357Gly: A Mutant with PC2-Like Activity"
10:28 am - 10:36 amDiscussion
10:36 am - 10:52 amFabienne Soulet (INSERM, University of Bordeaux)
"Importance of Apelin Processing by Furin-Like Enzymes in Angiogenesis and Tumorigenesis"
10:52 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session II
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component: Career Development
Discussion Leader: Jeroen Declercq (KU Leuven)
Panelists:
  • John Creemers (KU Leuven)
  • Hans-Ulrich Demuth (Fraunhofer-Institute Leipzig)
  • Paul Taghert (Washington University Medical)
  • Bette Phimister (Deputy Editor, NEJM)
  • Ken Pearce (GSK)
  • Peter Lyons (Teacher/Researcher, Andrews University)
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes

Contributors

Conference Links

Conference History Protein Processing, Trafficking and Secretion
Additional Fee Info

Protein Processing, Trafficking and Secretion
July 14 - 19, 2024


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