Saturday |
2:00 pm - 5:00 pm | Arrival and Check-in |
3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:45 pm - 4:30 pm | Keynote Session: Processing Enzymes of Endo-Lysosomes - Myths, Advances, and Challenges |
| Discussion Leader: Frederic Couture (Université de Sherbrooke, Canada) |
3:45 pm - 4:20 pm | Klaudia Brix (Jacobs University Bremen, Germany) "Processing Enzymes of Endo-Lysosomes - Myths, Advances, and Challenges" |
4:20 pm - 4:30 pm | Discussion |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Exploring the Basis of Trafficking and
Secretion |
| Discussion Leader: Linda van Keimpema (VU University Amsterdam, The Netherlands) |
7:30 pm - 7:45 pm | Xingmin Zhang (University of Wisconsin-Madison, USA) "A Novel Munc13/CAPS Family Protein, BAIAP3, Is Required for Regulated Exocytosis in Neuroendocrine Cells" |
7:45 pm - 7:50 pm | Discussion |
7:50 pm - 8:05 pm | Jessica Blackburn (University of Arkansas for Medical Sciences, USA) "Deletion of the Conserved Oligomeric Golgi Subunits Impairs Protein Trafficking and Glycosylation and Results in Dramatically Enlarged Endosomal/Lysosomal Compartments" |
8:05 pm - 8:10 pm | Discussion |
8:10 pm - 8:25 pm | Antonio Santos (Centre for Genomic Regulation (CRG), Spain) "The Novel Chimeric Protein Mia2/cTAGE5 Loads Pre-Chylomicrons/VLDLs at Endoplasmic Reticulum Exit Sites for Their Export" |
8:25 pm - 8:30 pm | Discussion |
8:30 pm - 8:45 pm | Alejandra Canales (University of Wisconsin-Madison, USA) "Using Toxoplasma gondii as a Model Organism to Study Protein Trafficking" |
8:45 pm - 8:50 pm | Discussion |
8:50 pm - 9:05 pm | Javier Emperador Melero (VU University Amsterdam, The Netherlands) "Development of Dense Core Vesicle Fusion and Trafficking in Human iPSC-Derived Neurons" |
9:05 pm - 9:10 pm | Discussion |
9:10 pm - 9:30 pm | General Discussion |
Sunday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Understanding Protein Processing and
Post-Translational Modifications |
| Discussion Leader: Stephanie Duval (Institut de Recherche Clinique de Montreal (IRCM), Université de Montréal, Canada) |
9:00 am - 9:15 am | Swe-Htet Naing (Georgia Institute of Technology, USA) "Catalytic Properties of Intramembrane Aspartyl Protease Substrate Hydrolysis Evaluated Using a FRET Peptide Cleavage Assay" |
9:15 am - 9:20 am | Discussion |
9:20 am - 9:35 am | Amro Mohammad (Goodman Cancer Research Centre, McGill University, Canada) "The PTEN/PACE4/[p]RR/mTORC1 Axis in Prostate Cancer Cell Progression" |
9:35 am - 9:40 am | Discussion |
9:40 am - 9:55 am | Bruno Ramos-Molina (KU Leuven, Belgium) "Inactivation of Furin in β Cells Results in β Cell Dysfunction and Activation of the ATF4 Pathway" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:15 am | James Checco (University of Illinois at Urbana-Champaign, USA) "Exploring the Signaling Pathways of D-Amino Acid-Containing Neuropeptides" |
10:15 am - 10:20 am | Discussion |
10:20 am - 10:35 am | Lorelei Durand (Institut de Recherche Clinique de Montreal (IRCM), Université de Montréal, Canada) "The Proprotein Convertase PC7: Regulation of Its Enzymatic Activity and Trafficking Through the Conventional Secretory Pathway" |
10:35 am - 10:40 am | Discussion |
10:40 am - 11:00 am | General Discussion |
11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:30 pm | Mentorship Component: Cutting Edge Methodologies in the Study of Protein Processing, Trafficking and Secretion |
| This technology-oriented talk and discussion will help train attendees in the use of recently
developed and impactful methods to study questions relevant to their on-going
research in novel ways. |
| Discussion Leader: Anna Jansen (University of Copenhagen, Denmark) |
1:30 pm - 1:50 pm | Lloyd Fricker (Albert Einstein College of Medicine, USA) "Developing New Methodologies to Study Protein Processing" |
1:50 pm - 2:00 pm | Discussion |
2:00 pm - 2:20 pm | Galia Blum (Hebrew University of Jerusalem, Israel) "How to Design and Generate Molecular Probes for Studying the Trafficking and Activity of Proteases" |
2:20 pm - 2:30 pm | Discussion |
2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
3:00 pm | Seminar Concludes |