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Protein Processing, Trafficking and Secretion (GRS)

Gordon Research Seminar

Novel Techniques to Identify Molecular Mechanisms of Protein Processing and Trafficking

July 14 - 15, 2018

Chairs

and

Colby-Sawyer College

541 Main Street

New London, New Hampshire, United States

Venue and Travel Information

Conference Description

The Gordon Research Seminar on Protein Processing, Trafficking and Secretion is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

This meeting will cover various advances in typical protein processing as well as unexpected roles of proteases. The meeting will also cover membrane dynamics and vesicle formation with a specific focus on novel technologies to address fundamental questions.

Related Meeting

This GRS will be held in conjunction with the "Protein Processing, Trafficking and Secretion" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
2:00 pm - 5:00 pm	Arrival and Check-in
3:30 pm - 3:45 pm	Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm	Keynote Session: Molecular Mechanism of Protein Processing and Trafficking Discussion Leader:
3:45 pm - 4:20 pm	"Molecular Mechanism of Protein Processing and Trafficking"
4:20 pm - 4:30 pm	Discussion
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Membrane and Vesicle Dynamics in Protein Trafficking and Secretion Discussion Leader:
7:30 pm - 7:45 pm	"The Conserved Coiled-Coil Protein CCCP1 and the Endosomal Complex EARP Regulate Dense-Core Vesicle Cargo Sorting"
7:45 pm - 7:50 pm	Discussion
7:50 pm - 8:05 pm	"Dynamin Is Required for Dense-Core Vesicle Exocytosis"
8:05 pm - 8:10 pm	Discussion
8:10 pm - 8:25 pm	"Trafficking of Pancreatic Hormone Amylin During Cellular Stress Condition"
8:25 pm - 8:30 pm	Discussion
8:30 pm - 8:45 pm	"The Role of Exocytic SNARE Complex Proteins Munc18-1, SNAP25 and Syntaxin-1 in Neuronal Viability"
8:45 pm - 8:50 pm	Discussion
8:50 pm - 9:05 pm	"CAB-1 Is Required at Two Dense Core Vesicle Trafficking Checkpoints"
9:05 pm - 9:10 pm	Discussion
9:10 pm - 9:30 pm	General Discussion
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Exploring the Basis, and Unexpected Functions, of Protein Processing and Trafficking in Health and Disease Discussion Leader:
9:00 am - 9:15 am	"Tissue-of-Origin Identification of Secreted Proteins in the Blood Using TurboID"
9:15 am - 9:20 am	Discussion
9:20 am - 9:35 am	"Substrates and Functions of ADAM10 in the Mammalian Nervous System"
9:35 am - 9:40 am	Discussion
9:40 am - 9:55 am	"Loss of Furin in β Cells Leads to mTORC1-Dependent Activation of the ATF4 Pathway and β Cell Dysfunction by Limiting Insulin Receptor Processing"
9:55 am - 10:00 am	Discussion
10:00 am - 10:15 am	"Regulation of Secretion Dynamics by the ER-Resident Intramembrane Protease RHBDL4"
10:15 am - 10:20 am	Discussion
10:20 am - 10:35 am	"A Novel Method for the Background-Free Purification of Age-Distinct Insulin Secretory Granules for Proteomic and Lipidomic Analyses"
10:35 am - 10:40 am	Discussion
10:40 am - 11:00 am	General Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Mentorship Component: Cutting Edge Analytical Measurement of Protein Processing Discussion Leader:
1:30 pm - 2:00 pm	"Measuring Prohormone Processing in Individual Cells Using Mass Spectrometry"
2:00 pm - 2:10 pm	Discussion
2:10 pm - 2:30 pm	Panel Discussion Career Options
2:30 pm - 3:00 pm	Evaluation Period Fill in GRS Evaluation Forms
3:00 pm	Seminar Concludes

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Conference History Protein Processing, Trafficking and Secretion

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